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| | MEAK7 | MTOR associated protein, eak-7 homolog. (456 aa) |
| | CLN3 | Battenin. (438 aa) |
| | SPNS1 | Sphingolipid transporter 1 (putative). (528 aa) |
| | ENSPPYP00000008037 | annotation not available (125 aa) |
| | CDIP1 | Cell death inducing p53 target 1. (208 aa) |
| | ATP6V0C | V-type H+-transporting ATPase 16kDa proteolipid subunit. (128 aa) |
| | CLCN7 | Chloride channel protein. (781 aa) |
| | ANPEP | Aminopeptidase. (892 aa) |
| | TM6SF1 | Transmembrane 6 superfamily member 1; May function as sterol isomerase. Belongs to the TM6SF family. (366 aa) |
| | SPG11 | SPG11 isoform 3. (2431 aa) |
| | VPS39 | VPS39 isoform 1. (875 aa) |
| | ABCD4 | ATP binding cassette subfamily D member 4. (606 aa) |
| | ZFYVE26 | ZFYVE26 isoform 2. (2539 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (232 aa) |
| | CHMP4A | CHMP4A isoform 4. (258 aa) |
| | LAMP1 | LAMP1 isoform 1. (368 aa) |
| | CLN5 | T0025243 isoform 1. (378 aa) |
| | SLC46A3 | Solute carrier family 46 member 3. (463 aa) |
| | LRMP | LRMP isoform 1. (496 aa) |
| | SLC15A4 | SLC15A4 isoform 1. (577 aa) |
| | SCARB1 | SCARB1 isoform 7; Belongs to the CD36 family. (471 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | TPCN1 | TPCN1 isoform 2. (798 aa) |
| | CKAP4 | CKAP4 isoform 3. (475 aa) |
| | GLIPR1 | GLI pathogenesis related 1; Belongs to the CRISP family. (266 aa) |
| | LRP1 | LRP1 isoform 1. (4377 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1. (155 aa) |
| | BORCS5 | BLOC-1 related complex subunit 5. (196 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | ITFG2 | KICSTOR complex protein ITFG2; As part of the KICSTOR complex functions in the amino acid- sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose. (447 aa) |
| | SIDT2 | SIDT2 isoform 3. (776 aa) |
| | PRCP | Lysosomal Pro-X carboxypeptidase; Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity); Belongs to the peptidase S28 family. (496 aa) |
| | CR201_G0023224 | MYO7A isoform 2. (1350 aa) |
| | NEU3 | NEU3 isoform 2. (404 aa) |
| | TMEM9B | TMEM9 domain family member B. (198 aa) |
| | SLC15A3 | Solute carrier family 15 member 3. (582 aa) |
| | CYB561A3 | Cytochrome b561 family member A3. (242 aa) |
| | TMEM179B | Transmembrane protein 179B. (219 aa) |
| | GPR137 | GPR137 isoform 14. (402 aa) |
| | SLC66A1 | PQLC2 isoform 1. (247 aa) |
| | LAPTM5 | Lysosomal-associated transmembrane protein 5; May have a special functional role during embryogenesis and in adult hematopoietic cells. (262 aa) |
| | MCOLN3 | MCOLN3 isoform 4. (553 aa) |
| | ENSPPYP00000001296 | annotation not available (120 aa) |
| | GBA | Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] (626 aa) |
| | TMEM9 | Transmembrane protein 9. (183 aa) |
| | ARL8A | ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | PIGR | PIGR isoform 1. (764 aa) |
| | GPR137B | G protein-coupled receptor 137B. (399 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (559 aa) |
| | CR201_G0031594 | TPCN2 isoform 7. (717 aa) |
| | ENSPPYP00000003382 | annotation not available (390 aa) |
| | IFITM10 | IFITM10 isoform 1. (130 aa) |
| | PI4K2A | Phosphatidylinositol 4-kinase type 2 alpha. (479 aa) |
| | FFAR4 | FFAR4 isoform 2. (318 aa) |
| | SLC29A3 | Solute carrier family 29 member 3. (475 aa) |
| | PSAP | PSAP isoform 2. (526 aa) |
| | AP3M1 | AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity); Belongs to the adaptor complexes medium subunit family. (418 aa) |
| | ENSPPYP00000002694 | annotation not available (159 aa) |
| | CLCN6 | CLCN6 isoform 2; Belongs to the chloride channel (TC 2.A.49) family. (824 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa) |
| | VNN3 | Vascular non-inflammatory molecule 3 isoform X1. (501 aa) |
| | ENSPPYP00000024559 | annotation not available (71 aa) |
| | TMEM63A | CSC1-like protein 1; Acts as an osmosensitive calcium-permeable cation channel (By similarity). Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion (By similarity). Belongs to the CSC1 (TC 1.A.17) family. (717 aa) |
| | RNF167 | Ring finger protein 167. (375 aa) |
| | WDR41 | WDR41 isoform 3. (419 aa) |
| | ATP11B | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (599 aa) |
| | TMEM150C | TMEM150C isoform 1. (278 aa) |
| | CLCN5 | H(+)/Cl(-) exchange transporter 5; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function (By similarity). (816 aa) |
| | BST2 | BST2 isoform 1. (200 aa) |
| | ATP6V0E1 | V-type proton ATPase subunit e 1; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa) |
| | GPR137C | GPR137C isoform 1. (258 aa) |
| | ATP6V1G1 | V-type H+-transporting ATPase subunit G. (115 aa) |
| | BRI3 | BRI3 isoform 4. (123 aa) |
| | VAMP7 | Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] (220 aa) |
| | ABCD1 | ABCD1 isoform 1. (710 aa) |
| | ATP6AP2 | Renin receptor extracellular fragment; Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton- transporting vacuolar (V)-ATPase protein pump. May mediate renin- dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity). Probably by controlling the assembly of the V- ATPase pump and thus the acidification of the endo-lysosomal system, plays a [...] (350 aa) |
| | CXorf21 | CXorf21 isoform 1. (301 aa) |
| | TLR8 | TLR8 isoform 1; Belongs to the Toll-like receptor family. (1041 aa) |
| | CLCN4 | Chloride channel protein. (760 aa) |
| | ABCA2 | ABCA2 isoform 9. (2330 aa) |
| | SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) |
| | SURF4 | Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family. (254 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | SLC2A8 | SLC2A8 isoform 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (477 aa) |
| | STOM | STOM isoform 3. (288 aa) |
| | B4GALT1 | Beta-1,4-galactosyltransferase 1. (398 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (465 aa) |
| | HGSNAT | HGSNAT isoform 1. (645 aa) |
| | RHEB | RHEB isoform 1. (167 aa) |
| | IQCA1L | IQCA1L isoform 1. (815 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (876 aa) |
| | MIOS | GATOR complex protein MIOS; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. (875 aa) |
| | TMEM106B | Transmembrane protein 106B. (274 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | ABCA13 | ABCA13 isoform 2. (4952 aa) |
| | TMEM130 | Transmembrane protein 130. (641 aa) |
| | TECPR1 | Tectonin beta-propeller repeat-containing protein 1; Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity); Belongs to the TECPR1 family. (1165 aa) |
| | CR201_G0016218-2 | HLA-DPA1 isoform 3. (239 aa) |
| | LOC100460187 | MHC class II protein; Belongs to the MHC class II family. (254 aa) |
| | CR201_G0016218 | HLA-DPA1 isoform 1; Belongs to the MHC class II family. (260 aa) |
| | HLA-DMA | HLA class II histocompatibility antigen, DM alpha chain isoform X1. (261 aa) |
| | LOC100448477 | HLA-DMB isoform 5. (263 aa) |
| | HLA-DOB | HLA class II histocompatibility antigen, DO beta chain. (272 aa) |
| | ENSPPYP00000019293 | HLA class II histocompatibility antigen, DRB1-11 beta chain isoform X1. (266 aa) |
| | VNN1 | VNN1 isoform 1. (513 aa) |
| | STX7 | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). (261 aa) |
| | OSTM1 | OSTM1 isoform 4. (295 aa) |
| | SLC17A5 | SLC17A5 isoform 1. (453 aa) |
| | LMBRD1 | LMBRD1 isoform 1. (518 aa) |
| | TFEB | TFEB isoform 3. (581 aa) |
| | CR201_G0016196 | HLA-DQB1 isoform 5. (304 aa) |
| | HLA-DRB5 | Ig-like domain-containing protein. (266 aa) |
| | ATP10B | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1460 aa) |
| | SLC36A1 | Solute carrier family 36 member 1. (476 aa) |
| | ANXA6 | Annexin. (660 aa) |
| | SLCO4C1 | Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by en [...] (724 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | SLC38A9 | SLC38A9 isoform 14. (541 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (534 aa) |
| | TLR3 | Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa) |
| | CLCN3 | H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity). (866 aa) |
| | TMEM192 | Transmembrane protein 192; Belongs to the TMEM192 family. (271 aa) |
| | MFSD8 | MFSD8 isoform 10. (518 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1177 aa) |
| | MANBA | MANBA isoform 1. (879 aa) |
| | SLC39A8 | SLC39A8 isoform 4. (424 aa) |
| | HPSE | HPSE isoform 1. (545 aa) |
| | SCARB2 | SCARB2 isoform 16; Belongs to the CD36 family. (478 aa) |
| | TMEM165 | GDT1 family protein. (324 aa) |
| | ATP8A1 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa) |
| | TMEM175 | TMEM175 isoform 4. (229 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | RNF13 | E3 ubiquitin-protein ligase RNF13; E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. (381 aa) |
| | CP | Ceruloplasmin; Belongs to the multicopper oxidase family. (1065 aa) |
| | DNAJC13 | DNAJC13 isoform 1. (2243 aa) |
| | ACPP | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (421 aa) |
| | CR201_G0007982 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | RAB7A | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] (208 aa) |
| | IQCA1 | IQCA1 isoform 1. (832 aa) |
| | ATG16L1 | Autophagy-related protein 16-1; Plays an essential role in autophagy: interacts with ATG12- ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway. Plays a r [...] (624 aa) |
| | LRP2 | LRP2 isoform 1. (4512 aa) |
| | LAPTM4A | Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. (233 aa) |
| | SLC35F6 | Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter (By similarity). (371 aa) |
| | VAMP8 | Vesicle-associated membrane protein 8; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t- SNARE complex. Also required for dense-granule secretion in platelets. Plays als [...] (253 aa) |
| | NFAM1 | NFAM1 isoform 1. (218 aa) |
| | TOM1 | TOM1 isoform 6; Belongs to the TOM1 family. (459 aa) |
| | ATP6V1E1 | ATP6V1E1 isoform 1. (203 aa) |
| | TRPM2 | TRPM2 isoform 3. (1302 aa) |
| | DNAJC5 | DnaJ heat shock protein family (Hsp40) member C5. (198 aa) |
| | EEF1A2 | EEF1A2 isoform 3. (415 aa) |
| | FPR1 | Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | NKG7 | Natural killer cell granule protein 7. (165 aa) |
| | SPHK2 | SPHK2 isoform 2. (635 aa) |
| | AP2S1 | AP-2 complex subunit sigma; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (142 aa) |
| | CEACAM6 | Carcinoembryonic antigen related cell adhesion molecule 6. (344 aa) |
| | RAB3D | RAB3D isoform 1. (194 aa) |
| | LDLR | LDLR isoform 3. (815 aa) |
| | LRRC8E | Leucine rich repeat containing 8 VRAC subunit E. (796 aa) |
| | UBXN6 | UBXN6 isoform 3. (436 aa) |
| | AZU1 | AZU1 isoform 1. (250 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | NPC1 | NPC1 isoform 1. (1243 aa) |
| | SEH1L | Nucleoporin SEH1; Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. Belongs to the WD repeat SEC13 family. (360 aa) |
| | SLC26A11 | SLC26A11 isoform 12. (622 aa) |
| | CR201_G0021330 | RAB37 isoform 13. (197 aa) |
| | RAB5C | Ras-related protein Rab-5C; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (216 aa) |
| | GRN | GRN isoform 1. (578 aa) |
| | NSF | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. (816 aa) |
| | SPAG9 | Sperm associated antigen 9. (1307 aa) |
| | AP2B1 | AP complex subunit beta. (951 aa) |
| | CD68 | CD68 isoform 1. (354 aa) |
| | TM4SF5 | Transmembrane 4 L six family member 5. (197 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (400 aa) |
| | CR201_G0041408 | WDR81 isoform 4. (691 aa) |
| | RILP | RILP isoform 2. (400 aa) |
| | CR201_G0054316 | LITAF isoform 8. (126 aa) |
