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| | KRAS | KRAS proto-oncogene, GTPase. (188 aa) |
| | PPFIBP1 | PPFIBP1 isoform 10. (1036 aa) |
| | TWF1 | Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily. (384 aa) |
| | SENP1 | Sentrin-specific protease 1; Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from [...] (684 aa) |
| | LIMA1 | LIMA1 isoform 1. (760 aa) |
| | TNS2 | TNS2 isoform 7. (1385 aa) |
| | LRP1 | LRP1 isoform 1. (4377 aa) |
| | AVIL | AVIL isoform 2. (819 aa) |
| | CSRP2 | Cysteine and glycine rich protein 2. (193 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (957 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (434 aa) |
| | GIT2 | GIT2 isoform 10. (759 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (168 aa) |
| | LOC100436554 | Disintegrin and metalloproteinase domain-containing protein 1-like. (837 aa) |
| | RPLP0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa) |
| | CR201_G0000922 | PXN isoform 2; Belongs to the paxillin family. (381 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | FLT1 | FLT1 isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa) |
| | LCP1 | Lymphocyte cytosolic protein 1. (627 aa) |
| | THSD1 | Thrombospondin type-1 domain-containing protein 1. (853 aa) |
| | LMO7 | LMO7 isoform 6. (1670 aa) |
| | EFNB2 | EFNB2 isoform 1; Belongs to the ephrin family. (333 aa) |
| | ARHGEF7 | ARHGEF7 isoform 7. (803 aa) |
| | MMP14 | Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...] (582 aa) |
| | EFS | Embryonal Fyn-associated substrate. (561 aa) |
| | FERMT2 | FERMT2 isoform 1. (623 aa) |
| | SYNE2 | SYNE2 isoform 1. (6862 aa) |
| | NUMB | NUMB endocytic adaptor protein. (651 aa) |
| | FLRT2 | Fibronectin leucine rich transmembrane protein 2. (660 aa) |
| | EVL | Ena/VASP-like protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization (By similarity). (422 aa) |
| | ZFYVE21 | Zinc finger FYVE-type containing 21. (234 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) |
| | TLN2 | TLN2 isoform 1. (2542 aa) |
| | MAP2K1 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. (395 aa) |
| | CORO2B | Coronin; Belongs to the WD repeat coronin family. (526 aa) |
| | CSPG4 | Uncharacterized protein. (2071 aa) |
| | PEAK1 | PEAK1 isoform 10. (1747 aa) |
| | ENSPPYP00000007589 | LOW QUALITY PROTEIN: chondroitin sulfate proteoglycan 4-like. (75 aa) |
| | TLNRD1 | TLNRD1 isoform 1. (291 aa) |
| | ENSPPYP00000007639 | annotation not available (73 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | PDPK1 | PDPK1 isoform 1. (495 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | BCAR1 | BCAR1 isoform 1. (849 aa) |
| | CDH13 | Cadherin-13; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth (By similarity). (700 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (118 aa) |
| | ALOX15B | ALOX15B isoform 2. (676 aa) |
| | MPRIP | MPRIP isoform 9. (2203 aa) |
| | CR201_G0033575 | GIT1 isoform 13. (542 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa) |
| | TNS4 | TNS4 isoform 2. (137 aa) |
| | GRB7 | GRB7 isoform 9. (532 aa) |
| | LASP1 | LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). (279 aa) |
| | MRC2 | MRC2 isoform 2. (1369 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1051 aa) |
| | YES1 | Tyrosine-protein kinase. (485 aa) |
| | MAPRE2 | Microtubule-associated protein RP/EB family member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity); Belongs to the MAPRE family. (327 aa) |
| | ENSPPYP00000010292 | annotation not available (287 aa) |
| | CNN2 | Calponin-2; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). (309 aa) |
| | CR201_G0055854 | C19orf35 isoform 1. (392 aa) |
| | CR201_G0044279 | PIP5K1C isoform 1. (576 aa) |
| | DNM2 | DNM2 isoform 6; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (866 aa) |
| | CALR | Calreticulin. (417 aa) |
| | ADGRE5 | ADGRE5 isoform 2; Belongs to the G-protein coupled receptor 2 family. (835 aa) |
| | TPM4 | TPM4 isoform 4; Belongs to the tropomyosin family. (260 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (645 aa) |
| | PLAUR | PLAUR isoform 2. (287 aa) |
| | PVR | PVR isoform 2. (274 aa) |
| | VASP | Vasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa) |
| | RRAS | RRAS isoform 1. (218 aa) |
| | ENSPPYP00000011654 | annotation not available (312 aa) |
| | CR201_G0047951 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (240 aa) |
| | ACTN2 | ACTN2 isoform 1. (887 aa) |
| | ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | ENAH | ENAH isoform 1. (579 aa) |
| | CAPN2 | CAPN2 isoform 2; Belongs to the peptidase C2 family. (655 aa) |
| | CSRP1 | Cysteine and glycine-rich protein 1; Could play a role in neuronal development. (193 aa) |
| | PTPRC | PTPRC isoform 2. (1267 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (986 aa) |
| | ENSPPYP00000000957 | annotation not available (292 aa) |
| | PIP5K1A | Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (549 aa) |
| | PRUNE1 | Prune exopolyphosphatase 1. (453 aa) |
| | BCAR3 | BCAR3 isoform 5. (837 aa) |
| | NEXN | NEXN isoform 3. (763 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | CR201_G0042751 | ASAP3 isoform 8. (517 aa) |
| | HSPG2 | HSPG2 isoform 1. (4326 aa) |
| | EPHA2 | EPHA2 isoform 1. (959 aa) |
| | ENSPPYP00000002410 | annotation not available (99 aa) |
| | ITGA8 | ITGA8 isoform 1; Belongs to the integrin alpha chain family. (948 aa) |
| | SVIL | SVIL isoform 3. (2214 aa) |
| | ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (887 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (923 aa) |
| | ARHGAP22 | ARHGAP22 isoform 1. (632 aa) |
| | SORBS1 | SORBS1 isoform 10. (1292 aa) |
| | CD151 | Tetraspanin. (253 aa) |
| | CTTN | CTTN isoform 1. (508 aa) |
| | CORO1B | Coronin-1B; Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction (By similarity); Belongs to the WD repeat coronin family. (510 aa) |
| | ENSPPYP00000003496 | annotation not available (383 aa) |
| | ARL14EP | ADP ribosylation factor like GTPase 14 effector protein. (260 aa) |
| | PARVA | PARVA isoform 1. (412 aa) |
| | RHOG | Ras homolog family member G. (191 aa) |
| | RDX | RDX isoform 3. (604 aa) |
| | LAYN | LAYN isoform 3. (374 aa) |
| | REXO2 | RNA exonuclease 2. (237 aa) |
| | MCAM | Melanoma cell adhesion molecule. (646 aa) |
| | CD9 | Tetraspanin. (206 aa) |
| | ENSPPYP00000024273 | annotation not available (160 aa) |
| | RSU1 | Ras suppressor protein 1. (277 aa) |
| | CR201_G0055900-2 | LIMS1 isoform 8. (272 aa) |
| | ENSPPYP00000024179 | 14-3-3 protein epsilon-like isoform X1. (173 aa) |
| | MAP2K2 | MAP2K2 isoform 6. (213 aa) |
| | UBOX5 | UBOX5 isoform 2. (512 aa) |
| | HCK | Tyrosine-protein kinase. (449 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | TGM2 | Transglutaminase 2. (687 aa) |
| | YWHAB | 14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] (262 aa) |
| | CASS4 | Cas scaffold protein family member 4. (786 aa) |
| | ENSPPYP00000013053 | annotation not available (293 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | CDC42EP1 | CDC42EP1 isoform 1. (391 aa) |
| | PARVB | Parvin beta. (334 aa) |
| | ENSPPYP00000013398 | annotation not available (195 aa) |
| | MAP4K4 | MAP4K4 isoform 3. (1191 aa) |
| | FHL2 | FHL2 isoform 4. (459 aa) |
| | LIMS1 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (392 aa) |
| | FBLN7 | FBLN7 isoform 1. (439 aa) |
| | YWHAQ | 14-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity). (245 aa) |
| | LIMS2 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (327 aa) |
| | RND3 | Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. (244 aa) |
| | ITGA6 | ITGA6 isoform 6; Belongs to the integrin alpha chain family. (1113 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) |
| | ENSPPYP00000014638 | annotation not available (242 aa) |
| | TNS1 | TNS1 isoform 2. (1727 aa) |
| | ALCAM | Activated leukocyte cell adhesion molecule. (583 aa) |
| | FAM107A | Actin-associated protein FAM107A; Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F- actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal [...] (144 aa) |
| | FLNB | FLNB isoform 3. (2536 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | LPP | LIM domain containing preferred translocation partner in lipoma. (612 aa) |
| | LMLN | Leishmanolysin-like peptidase. (358 aa) |
| | AFAP1 | Actin filament associated protein 1. (814 aa) |
| | SCARB2 | SCARB2 isoform 16; Belongs to the CD36 family. (478 aa) |
| | ARHGAP24 | Rho GTPase activating protein 24. (748 aa) |
| | SYNPO2 | SYNPO2 isoform 1. (1261 aa) |
| | ANXA5 | Annexin. (320 aa) |
| | PALLD | PALLD isoform 1. (1101 aa) |
| | IRF2 | Interferon regulatory factor. (349 aa) |
| | FAT1 | FAT1 isoform 1. (4591 aa) |
| | DAB2 | DAB adaptor protein 2. (770 aa) |
| | ANXA6 | Annexin. (660 aa) |
| | NPM1 | NPM1 isoform 1. (274 aa) |
| | PDLIM7 | PDZ and LIM domain 7. (423 aa) |
| | ENSPPYP00000018135 | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (503 aa) |
| | NEDD9 | NEDD9 isoform 1. (834 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (331 aa) |
| | GJA1 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa) |
| | AKAP12 | AKAP12 isoform 1. (1783 aa) |
| | EZR | EZR isoform 1. (586 aa) |
| | IGF2R | IGF2R isoform 1. (2446 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | GNB2 | GNB2 isoform 1. (340 aa) |
| | TRIP6 | Thyroid hormone receptor interactor 6. (476 aa) |
| | YWHAG | 14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. (247 aa) |
| | ENSPPYP00000019656 | annotation not available (239 aa) |
| | TNS3 | TNS3 isoform 1. (1514 aa) |
| | RALA | RAS like proto-oncogene A. (206 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (649 aa) |
| | ABCB4 | ABCB4 isoform 3. (1223 aa) |
| | ENSPPYP00000020088 | annotation not available (138 aa) |
| | FLNC | FLNC isoform 2. (2708 aa) |
| | ENSPPYP00000024178 | annotation not available (136 aa) |
| | ACTN3 | Actinin alpha 2/3. (388 aa) |
| | PTPRA | Receptor-type tyrosine-protein phosphatase alpha. (840 aa) |
| | MAPK1 | Mitogen-activated protein kinase 1 isoform X1. (158 aa) |
| | RRAS2 | RRAS2 isoform 1. (168 aa) |
| | FLNA | FLNA isoform 7. (2647 aa) |
| | L1CAM | L1 cell adhesion molecule. (1257 aa) |
| | FHL1 | FHL1 isoform 22. (339 aa) |
| | ENSPPYP00000023003 | annotation not available (72 aa) |
| | STARD8 | STARD8 isoform 4. (1107 aa) |
| | MSN | MSN isoform 6. (577 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | ENSPPYP00000022712 | annotation not available (241 aa) |
| | NHS | NHS actin remodeling regulator. (1474 aa) |
| | ENG | ENG isoform 3. (668 aa) |
| | GSN | GSN isoform 1. (732 aa) |
| | JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1132 aa) |
| | FOCAD | FOCAD isoform 1. (1801 aa) |
| | TLN1 | TLN1 isoform 1. (2541 aa) |
| | PTK2 | PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa) |
| | ENSPPYP00000021091 | annotation not available (270 aa) |
| | CPNE3 | Copine-3; Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation; Belongs to the copine family. (537 aa) |
| | ENSPPYP00000020880 | annotation not available (223 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | PTK2B | PTK2B isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | SORBS3 | SORBS3 isoform 3. (671 aa) |
| | DLC1 | DLC1 isoform 1. (1515 aa) |
| | PRAG1 | PRAG1 isoform 1. (1402 aa) |
| | ENSPPYP00000020360 | annotation not available (272 aa) |
| | ZYX | ZYX isoform 1. (559 aa) |
