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| | PSD | PSD isoform 2. (982 aa) |
| | OBSCN | OBSCN isoform 2. (7677 aa) |
| | CDC42BPA | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1690 aa) |
| | PLEKHA6 | PLEKHA6 isoform 2. (1024 aa) |
| | RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2. (583 aa) |
| | RASAL2 | RASAL2 isoform 1. (1269 aa) |
| | ARHGEF2 | Rho/Rac guanine nucleotide exchange factor 2. (986 aa) |
| | OSBPL9 | Oxysterol-binding protein-related protein 9; Belongs to the OSBP family. (736 aa) |
| | CR201_G0042751 | ASAP3 isoform 8. (517 aa) |
| | KIF1B | KIF1B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1790 aa) |
| | PLEKHG5 | PLEKHG5 isoform 5. (905 aa) |
| | PLCH2 | Phosphoinositide phospholipase C. (1416 aa) |
| | ACAP3 | ACAP3 isoform 1. (563 aa) |
| | ARHGAP22 | ARHGAP22 isoform 1. (632 aa) |
| | RTKN2 | RTKN2 isoform 2. (609 aa) |
| | PLEKHS1 | PLEKHS1 isoform 7. (459 aa) |
| | CR201_G0054746 | AGAP5 isoform 2. (662 aa) |
| | PHLDA2 | Pleckstrin homology like domain family A member 2. (155 aa) |
| | GRK2 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa) |
| | SPTBN2 | Spectrin beta chain; Belongs to the spectrin family. (2389 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (808 aa) |
| | SBF2 | SET binding factor 2. (1849 aa) |
| | SWAP70 | Switching B cell complex subunit SWAP70. (585 aa) |
| | GAB2 | GRB2 associated binding protein 2. (638 aa) |
| | ARHGAP20 | Rho GTPase activating protein 20. (1191 aa) |
| | PHLDB1 | PHLDB1 isoform 1. (1423 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) |
| | PLEKHG6 | PLEKHG6 isoform 1. (790 aa) |
| | PLEKHA5 | PLEKHA5 isoform 2. (1151 aa) |
| | FGD4 | FYVE, RhoGEF and PH domain containing 4. (766 aa) |
| | ARHGAP9 | ARHGAP9 isoform 2. (802 aa) |
| | ARHGEF25 | ARHGEF25 isoform 6. (473 aa) |
| | AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1192 aa) |
| | OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (889 aa) |
| | PLEKHG7 | PLEKHG7 isoform 2. (352 aa) |
| | APPL2 | APPL2 isoform 1. (564 aa) |
| | RASAL1 | RASAL1 isoform 2. (782 aa) |
| | SPATA13 | SPATA13 isoform 1. (1274 aa) |
| | DGKH | Diacylglycerol kinase. (1241 aa) |
| | FARP1 | FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). (1045 aa) |
| | DOCK9 | DOCK9 isoform 5; Belongs to the DOCK family. (2107 aa) |
| | ARHGEF7 | ARHGEF7 isoform 7. (803 aa) |
| | MCF2L | MCF2L isoform 10. (1211 aa) |
| | RASA3 | RASA3 isoform 1. (833 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | FERMT2 | FERMT2 isoform 1. (623 aa) |
| | CR201_G0009827 | Spectrin beta chain; Belongs to the spectrin family. (1818 aa) |
| | PLEK2 | PLEK2 isoform 1. (353 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa) |
| | TBC1D2B | TBC1D2B isoform 2. (790 aa) |
| | AKAP13 | AKAP13 isoform 5. (2833 aa) |
| | DOK4 | Docking protein 4; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells (By similarity). (326 aa) |
| | PLEKHG4 | PLEKHG4 isoform 2. (989 aa) |
| | ABR | ABR isoform 1. (818 aa) |
| | MPRIP | MPRIP isoform 9. (2203 aa) |
| | ARHGAP27 | ARHGAP27 isoform 2. (607 aa) |
| | GRB7 | GRB7 isoform 9. (532 aa) |
| | CYTH1 | CYTH1 isoform 4. (399 aa) |
| | SKAP1 | SKAP1 isoform 2. (347 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (437 aa) |
| | DOK6 | Docking protein 6. (331 aa) |
| | PLEKHJ1 | PLEKHJ1 isoform 1. (149 aa) |
| | CR201_G0051707 | T0183294 isoform 1. (932 aa) |
| | DNM2 | DNM2 isoform 6; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (866 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CR201_G0043999 | SPTBN4 isoform 1. (2409 aa) |
| | CR201_G0044078 | ARHGEF1 isoform 7. (764 aa) |
| | PHLDB3 | PHLDB3 isoform 2. (396 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (801 aa) |
| | PLEKHA4 | PLEKHA4 isoform 2. (725 aa) |
| | EXOC8 | EXOC8 isoform 1. (728 aa) |
| | FERMT1 | Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. (677 aa) |
| | ELMO2 | Engulfment and cell motility protein 2; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity). (720 aa) |
| | DOK5 | Docking protein 5. (270 aa) |
| | TIAM1 | TIAM1 isoform 1. (1591 aa) |
| | ITSN1 | ITSN1 isoform 4. (1610 aa) |
| | OSBP2 | Oxysterol-binding protein; Belongs to the OSBP family. (829 aa) |
| | CYTH4 | CYTH4 isoform 2. (394 aa) |
| | TRIOBP | TRIOBP isoform 1. (2199 aa) |
| | PHETA2 | PH domain containing endocytic trafficking adaptor 2. (259 aa) |
| | SBF1 | SBF1 isoform 1. (1900 aa) |
| | CR201_G0043139 | PSD4 isoform 2. (721 aa) |
| | DOK1 | Docking protein 1. (481 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2342 aa) |
| | PLEKHH2 | Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa) |
| | SOS1 | SOS1 isoform 2. (1290 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | PLEKHB2 | Pleckstrin homology domain-containing family B member 2; Involved in retrograde transport of recycling endosomes. (222 aa) |
| | ARHGEF4 | ARHGEF4 isoform 1. (1000 aa) |
| | ARHGAP15 | ARHGAP15 isoform 1. (475 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (959 aa) |
| | PLEKHA3 | Pleckstrin homology domain containing A3. (300 aa) |
| | PLCL1 | Phosphoinositide phospholipase C. (1016 aa) |
| | RAPH1 | RAPH1 isoform 10. (1303 aa) |
| | PLEKHM3 | Pleckstrin homology domain containing M3. (761 aa) |
| | PLCD4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration [...] (762 aa) |
| | DOCK10 | DOCK10 isoform 2; Belongs to the DOCK family. (1145 aa) |
| | NGEF | Ephexin-1; Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity). (708 aa) |
| | DGKD | Diacylglycerol kinase. (1106 aa) |
| | KALRN | KALRN isoform 1. (2858 aa) |
| | ARHGEF3 | Rho guanine nucleotide exchange factor 3; Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases. (526 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (756 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1127 aa) |
| | ARHGEF26 | ARHGEF26 isoform 4. (870 aa) |
| | VEPH1 | VEPH1 isoform 1. (793 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | SH3BP2 | SH3BP2 isoform 3. (563 aa) |
| | STAP1 | STAP1 isoform 1. (294 aa) |
| | ARHGAP24 | Rho GTPase activating protein 24. (748 aa) |
| | DAPP1 | Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa) |
| | ARHGAP10 | Rho GTPase activating protein 10. (786 aa) |
| | MYO10 | MYO10 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2027 aa) |
| | ARHGEF28 | ARHGEF28 isoform 1. (669 aa) |
| | CERT1 | Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner. (548 aa) |
| | ARHGAP26 | Rho GTPase activating protein 26. (814 aa) |
| | AFAP1L1 | AFAP1L1 isoform 2. (734 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | SYNGAP1 | SYNGAP1 isoform 3. (1304 aa) |
| | IPCEF1 | IPCEF1 isoform 2. (437 aa) |
| | TIAM2 | TIAM2 isoform 10. (1675 aa) |
| | RASA4B | T0142405 isoform 1. (806 aa) |
| | GRB10 | GRB10 isoform 1. (594 aa) |
| | ELMO1 | ELMO1 isoform 1. (715 aa) |
| | SKAP2 | Src kinase-associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway (By similarity). Belongs to the SKAP family. (359 aa) |
| | CADPS2 | CADPS2 isoform 1. (1197 aa) |
| | PSD3 | PSD3 isoform 1. (974 aa) |
| | DOK2 | Docking protein 2. (412 aa) |
| | PLEKHA2 | PLEKHA2 isoform 1. (302 aa) |
| | CR201_G0026651 | SNTG1 isoform 1. (377 aa) |
| | ARHGEF39 | ARHGEF39 isoform 2. (335 aa) |
| | FGD3 | FYVE, RhoGEF and PH domain-containing protein 3; Promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity). (737 aa) |
| | DAB2IP | DAB2IP isoform 2. (1130 aa) |
| | CR201_G0027646 | RALGPS1 isoform 3. (486 aa) |
| | NIBAN2 | FAM129B isoform 2. (702 aa) |
| | GAB4 | GAB4 isoform 1. (442 aa) |
| | CR201_G0049527 | IQSEC2 isoform 7. (773 aa) |
| | ARHGEF9 | Rho guanine nucleotide exchange factor 9; Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters (By similarity). (523 aa) |
| | OPHN1 | OPHN1 isoform 1. (802 aa) |
| | IRS4 | Insulin receptor substrate 4. (1262 aa) |
| | DOCK11 | DOCK11 isoform 1; Belongs to the DOCK family. (2065 aa) |
| | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa) |
| | GAB3 | GRB2 associated binding protein 3. (586 aa) |
| | ARAP3 | ARAP3 isoform 1. (830 aa) |
| | PLEKHA1 | PLEKHA1 isoform 4. (383 aa) |
| | CR201_G0034363 | SH2B1 isoform 11. (426 aa) |
