STRINGSTRING
TSPAN18 TSPAN18 TSPAN3 TSPAN3 TSPAN8 TSPAN8 CD9 CD9 TSPAN9 TSPAN9 CD82 CD82 CR201_G0045814 CR201_G0045814 TSPAN4 TSPAN4 TSPAN1 TSPAN1 TSPAN2 TSPAN2 CD37 CD37 TSPAN5 TSPAN5 TSPAN17 TSPAN17 TSPAN12 TSPAN12 TSPAN6 TSPAN6 CR201_G0036515 CR201_G0036515
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSPAN18Tetraspanin. (258 aa)
TSPAN3Tetraspanin-3; Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair. (253 aa)
TSPAN8Tetraspanin-8. (237 aa)
CD9Tetraspanin. (206 aa)
TSPAN9Tetraspanin. (236 aa)
CD82Tetraspanin. (267 aa)
CR201_G0045814Tetraspanin. (246 aa)
TSPAN4Tetraspanin-4; Belongs to the tetraspanin (TM4SF) family. (257 aa)
TSPAN1Tetraspanin-1. (241 aa)
TSPAN2Tetraspanin. (221 aa)
CD37Tetraspanin. (266 aa)
TSPAN5Tetraspanin. (268 aa)
TSPAN17Tetraspanin. (329 aa)
TSPAN12Tetraspanin-12; Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt- dependent activation of FZD4, suggesting the existence of a Wnt- independent signaling that also [...] (305 aa)
TSPAN6Tetraspanin-6. (245 aa)
CR201_G0036515Tetraspanin. (271 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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