10 items (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Your Input:
	STX1A	Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...] (259 aa)
	STX11	STX11 isoform 1; Belongs to the syntaxin family. (287 aa)
	STX7	Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity). (261 aa)
	STX5	STX5 isoform 1; Belongs to the syntaxin family. (355 aa)
	STX12	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity). (274 aa)
	STX3	STX3 isoform 3; Belongs to the syntaxin family. (289 aa)
	STX1B	STX1B isoform 1; Belongs to the syntaxin family. (590 aa)
	STX8	STX8 isoform 2. (236 aa)
	STX16	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa)
	STX19	Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR). (294 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
STX11	STX12	ENSPPYP00000019114	ENSPPYP00000001911	STX11 isoform 1; Belongs to the syntaxin family.	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	0.560
STX11	STX16	ENSPPYP00000019114	ENSPPYP00000012482	STX11 isoform 1; Belongs to the syntaxin family.	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	0.586
STX11	STX19	ENSPPYP00000019114	ENSPPYP00000015239	STX11 isoform 1; Belongs to the syntaxin family.	Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR).	0.900
STX11	STX5	ENSPPYP00000019114	ENSPPYP00000003630	STX11 isoform 1; Belongs to the syntaxin family.	STX5 isoform 1; Belongs to the syntaxin family.	0.631
STX11	STX7	ENSPPYP00000019114	ENSPPYP00000019051	STX11 isoform 1; Belongs to the syntaxin family.	Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity).	0.529
STX11	STX8	ENSPPYP00000019114	ENSPPYP00000008962	STX11 isoform 1; Belongs to the syntaxin family.	STX8 isoform 2.	0.582
STX12	STX11	ENSPPYP00000001911	ENSPPYP00000019114	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	STX11 isoform 1; Belongs to the syntaxin family.	0.560
STX12	STX16	ENSPPYP00000001911	ENSPPYP00000012482	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	0.620
STX12	STX1A	ENSPPYP00000001911	ENSPPYP00000019613	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...]	0.820
STX12	STX3	ENSPPYP00000001911	ENSPPYP00000003718	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	STX3 isoform 3; Belongs to the syntaxin family.	0.590
STX12	STX5	ENSPPYP00000001911	ENSPPYP00000003630	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	STX5 isoform 1; Belongs to the syntaxin family.	0.700
STX12	STX7	ENSPPYP00000001911	ENSPPYP00000019051	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes (By similarity).	0.904
STX12	STX8	ENSPPYP00000001911	ENSPPYP00000008962	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	STX8 isoform 2.	0.938
STX16	STX11	ENSPPYP00000012482	ENSPPYP00000019114	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	STX11 isoform 1; Belongs to the syntaxin family.	0.586
STX16	STX12	ENSPPYP00000012482	ENSPPYP00000001911	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	Syntaxin-12; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity). Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).	0.620
STX16	STX19	ENSPPYP00000012482	ENSPPYP00000015239	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	Syntaxin-19; Plays a role in endosomal trafficking of the epidermal growth factor receptor (EGFR).	0.452
STX16	STX1A	ENSPPYP00000012482	ENSPPYP00000019613	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	Syntaxin-1A; Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final [...]	0.641
STX16	STX1B	ENSPPYP00000012482	ENSPPYP00000008248	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	STX1B isoform 1; Belongs to the syntaxin family.	0.463
STX16	STX3	ENSPPYP00000012482	ENSPPYP00000003718	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	STX3 isoform 3; Belongs to the syntaxin family.	0.641
STX16	STX5	ENSPPYP00000012482	ENSPPYP00000003630	STX16-NPEPL1 isoform 1; Belongs to the syntaxin family.	STX5 isoform 1; Belongs to the syntaxin family.	0.521