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| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | CSDE1 | Cold shock domain containing E1. (798 aa) |
| | NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | BCL10 | BCL10 isoform 1. (263 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | CR201_G0053435 | UBB isoform 1. (128 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (438 aa) |
| | CHUK | CHUK isoform 1. (746 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | PSMB5 | Proteasome subunit beta type-5; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (263 aa) |
| | ENSPPYP00000006146 | annotation not available (173 aa) |
| | UBC | UBC isoform 2. (625 aa) |
| | PSMD9 | PSMD9 isoform 1. (223 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (188 aa) |
| | ENSPPYP00000004148 | annotation not available (164 aa) |
| | PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (263 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
| | ENSPPYP00000003414 | annotation not available (440 aa) |
| | BTRC | BTRC isoform 2. (605 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | ENSPPYP00000003305 | annotation not available (159 aa) |
| | ENSPPYP00000019816 | annotation not available (197 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | CR201_G0040641 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (143 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (306 aa) |
| | CARD11 | CARD11 isoform 1. (1155 aa) |
| | PSMB9 | Proteasome subunit beta. (218 aa) |
| | PSMB8 | Proteasome subunit beta. (272 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] (606 aa) |
| | NFKBIE | NFKBIE isoform 1. (361 aa) |
| | LOC100439093 | Peptidyl-prolyl cis-trans isomerase A (cyclophilin A). (168 aa) |
| | FBXW11 | FBXW11 isoform 1. (489 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (163 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (514 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. (909 aa) |
| | LOC112132763 | Peptidyl-prolyl cis-trans isomerase A (cyclophilin A). (167 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | ENSPPYP00000014644 | annotation not available (149 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | RASGRP3 | RASGRP3 isoform 1. (688 aa) |
| | CALM1-2 | Calmodulin 2. (149 aa) |
| | PSME4 | Proteasome activator subunit 4. (1843 aa) |
| | REL | REL proto-oncogene, NF-kB subunit. (587 aa) |
| | WDR92 | WDR92 isoform 1. (765 aa) |
| | PSMA7 | Proteasome subunit alpha type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (248 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28 (By similarity). (271 aa) |
| | FKBP1A | Peptidylprolyl isomerase. (108 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | NFKBIB | NFKBIB isoform 6. (354 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S14 family. (350 aa) |
| | ENSPPYP00000010984 | annotation not available (156 aa) |
| | UBA52 | UBA52 isoform 10. (128 aa) |
| | NFATC1 | NFATC1 isoform 10. (766 aa) |
| | MALT1 | MALT1 isoform 1. (774 aa) |
| | PSMA8 | Proteasome subunit alpha type. (256 aa) |
| | ENSPPYP00000009931 | annotation not available (76 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit p55 family. (456 aa) |
| | PSMC5 | PSMC5 isoform 2; Belongs to the AAA ATPase family. (406 aa) |
| | PSMB3 | Proteasome subunit beta. (218 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (254 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | ENSPPYP00000008980 | annotation not available (158 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | NFAT5 | Nuclear factor of activated T cells 5. (1529 aa) |
| | PSMA5 | Proteasome subunit alpha type. (278 aa) |
| | PSMD3 | PSMD3 isoform 1. (536 aa) |
| | PSMD4 | PSMD4 isoform 1. (384 aa) |
| | PSMA6 | Proteasome endopeptidase complex. (167 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | LOC100457600 | Proteasome subunit beta type-5-like. (263 aa) |
| | ENSPPYP00000023569 | annotation not available (247 aa) |
| | ENSPPYP00000023562 | annotation not available (156 aa) |
| | ENSPPYP00000023561 | annotation not available (122 aa) |
| | PSMD7 | PSMD7 isoform 1. (324 aa) |
| | PSMB1-2 | Proteasome subunit beta type-1. (241 aa) |
| | ENSPPYP00000023500 | annotation not available (140 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | ENSPPYP00000022487 | annotation not available (153 aa) |
| | PSMD13 | PSMD13 isoform 6. (376 aa) |
| | ENSPPYP00000022319 | annotation not available (162 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | PSMD5 | PSMD5 isoform 8. (97 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (697 aa) |
| | CUL1 | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...] (776 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1068 aa) |
| | CR201_G0036702 | CCDC71L isoform 2. (316 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) |
| | ENSPPYP00000019828 | annotation not available (154 aa) |
| | PSMB10 | Proteasome subunit beta. (256 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | CR201_G0003353 | RPS27A isoform 1. (155 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | RASGRP1 | RASGRP1 isoform 2. (787 aa) |
| | CALM1 | Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity). (149 aa) |
| | LOC100446892 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | NFKBIA | NFKBIA isoform 1. (317 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
