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IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa) | ||||
S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa) | ||||
SIKE1 | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity). (207 aa) | ||||
CR201_G0053435 | UBB isoform 1. (128 aa) | ||||
ISG15 | ISG15 ubiquitin like modifier. (165 aa) | ||||
CHUK | CHUK isoform 1. (746 aa) | ||||
NFKB2 | NFKB2 isoform 4. (868 aa) | ||||
IRF7 | IRF7 isoform 12. (396 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
TKFC | Triokinase and FMN cyclase. (575 aa) | ||||
UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (604 aa) | ||||
SAA2 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) | ||||
NLRX1 | NLRX1 isoform 1. (974 aa) | ||||
PCBP2 | Poly(rC) binding protein 2. (362 aa) | ||||
TBK1 | TANK binding kinase 1. (729 aa) | ||||
UBC | UBC isoform 2. (625 aa) | ||||
ENSPPYP00000006214 | annotation not available (312 aa) | ||||
HMGB1 | High mobility group box 1. (215 aa) | ||||
NFKBIA | NFKBIA isoform 1. (317 aa) | ||||
HSP90AA1 | HSP90AA1 isoform 6. (615 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) | ||||
CR201_G0003353 | RPS27A isoform 1. (155 aa) | ||||
CREBBP | CREBBP isoform 1. (2328 aa) | ||||
CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD; Deubiquitinase that specifically cleaves 'Lys-63'- and linear 'Met-1'-linked polyubiquitin chains and is involved in NF-kappa-B activation and TNF-alpha-induced necroptosis. Plays an important role in the regulation of pathways leading to NF-kappa-B activation. Contributes to the regulation of cell survival, proliferation and differentiation via its effects on NF-kappa-B activation. Negative regulator of Wnt signaling. Inhibits HDAC6 and thereby promotes acetylation of alpha-tubulin and stabilization of microtubules. Plays a role in the regul [...] (956 aa) | ||||
NLRC5 | NLRC5 isoform 2. (1632 aa) | ||||
RNF135 | Ring finger protein 135. (432 aa) | ||||
TRIM25 | Tripartite motif containing 25. (630 aa) | ||||
NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) | ||||
RNF125 | RNF125 isoform 1. (196 aa) | ||||
PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) | ||||
NFKBIB | NFKBIB isoform 6. (354 aa) | ||||
IRF3 | IRF3 isoform 6. (427 aa) | ||||
MAVS | MAVS isoform 2. (539 aa) | ||||
ITCH | E3 ubiquitin-protein ligase. (849 aa) | ||||
APP | APP isoform 3. (736 aa) | ||||
S100B | Protein S100; Belongs to the S-100 family. (92 aa) | ||||
ENSPPYP00000013015 | annotation not available (211 aa) | ||||
EP300 | EP300 isoform 1. (2380 aa) | ||||
TANK | TANK isoform 2. (424 aa) | ||||
IFIH1 | IFIH1 isoform 1. (1024 aa) | ||||
CASP10 | CASP10 isoform 3; Belongs to the peptidase C14A family. (521 aa) | ||||
CASP8 | CASP8 isoform 1; Belongs to the peptidase C14A family. (496 aa) | ||||
TOMM70 | Translocase of outer mitochondrial membrane 70. (608 aa) | ||||
ENSPPYP00000015333 | annotation not available (74 aa) | ||||
UBA7 | UBA7 isoform 1; Belongs to the ubiquitin-activating E1 family. (956 aa) | ||||
NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) | ||||
ENSPPYP00000016040 | LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5. (166 aa) | ||||
UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) | ||||
ENSPPYP00000016659 | annotation not available (592 aa) | ||||
HERC5 | HERC5 isoform 1. (433 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) | ||||
ENSPPYP00000016980 | annotation not available (100 aa) | ||||
ENSPPYP00000017056 | annotation not available (412 aa) | ||||
ENSPPYP00000017058 | annotation not available (377 aa) | ||||
ENSPPYP00000017062 | annotation not available (62 aa) | ||||
MAP3K1 | MAP3K1 isoform 1. (1505 aa) | ||||
ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct [...] (187 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (671 aa) | ||||
AGER | AGER isoform 1. (352 aa) | ||||
HSP90AB1 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa) | ||||
ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3- like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is ess [...] (275 aa) | ||||
TNFAIP3 | TNFAIP3 isoform 1. (790 aa) | ||||
RNF216 | Ring finger protein 216. (866 aa) | ||||
TRIM4 | Tripartite motif containing 4. (474 aa) | ||||
VWC2 | Von Willebrand factor C domain containing 2. (325 aa) | ||||
TAX1BP1 | Tax1-binding protein 1 homolog; Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti- apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity). (771 aa) | ||||
CR201_G0036702 | CCDC71L isoform 2. (316 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (697 aa) | ||||
DDX58 | DDX58 isoform 2. (875 aa) | ||||
IFNA8 | IFNA5 isoform 1. (189 aa) | ||||
LOC100433301 | IFNA13 isoform 1. (189 aa) | ||||
CR201_G0001880 | IFNA1 isoform 1. (189 aa) | ||||
IFNA6 | IFNA6 isoform 1. (189 aa) | ||||
IFNA5 | IFNA8 isoform 1. (189 aa) | ||||
IFNA14 | Interferon alpha 14. (189 aa) | ||||
IFNA21 | Interferon alpha 21. (189 aa) | ||||
ENSPPYP00000021491 | annotation not available (138 aa) | ||||
IFNB1 | Interferon beta 1. (187 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa) | ||||
IFNA21-2 | Interferon alpha-21. (153 aa) | ||||
ENSPPYP00000022638 | annotation not available (210 aa) | ||||
OTUD5 | OTUD5 isoform 2. (533 aa) | ||||
IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (487 aa) | ||||
ENSPPYP00000023500 | annotation not available (140 aa) | ||||
ENSPPYP00000023537 | annotation not available (121 aa) | ||||
ENSPPYP00000023562 | annotation not available (156 aa) |