Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP1B4 | MAPK1 | ENSPPYP00000023151 | ENSPPYP00000023664 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Mitogen-activated protein kinase 1 isoform X1. | 0.900 |
| ATP1B4 | MAPK3 | ENSPPYP00000023151 | ENSPPYP00000008184 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.900 |
| ATP1B4 | SMAD7 | ENSPPYP00000023151 | ENSPPYP00000010278 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | Mothers against decapentaplegic homolog. | 0.630 |
| ATP1B4 | SNW1 | ENSPPYP00000023151 | ENSPPYP00000006859 | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | SNW domain-containing protein 1; Involved in pre-mRNA splicing as component of the spliceosome. Is required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA. Is proposed to recruit PPIL1 to the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA. Involved in transcriptional regulation. Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, [...] | 0.816 |
| BAMBI | SMAD2 | ENSPPYP00000002537 | ENSPPYP00000010275 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator [...] | 0.552 |
| BAMBI | SMAD3 | ENSPPYP00000002537 | ENSPPYP00000007465 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.530 |
| BAMBI | SMAD4 | ENSPPYP00000002537 | ENSPPYP00000010297 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.530 |
| BAMBI | SMAD7 | ENSPPYP00000002537 | ENSPPYP00000010278 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.964 |
| BAMBI | TGFB1 | ENSPPYP00000002537 | ENSPPYP00000011208 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.743 |
| BAMBI | TGFBR1 | ENSPPYP00000002537 | ENSPPYP00000021783 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.983 |
| BAMBI | TGFBR2 | ENSPPYP00000002537 | ENSPPYP00000015718 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.641 |
| CBL | CR201_G0003353 | ENSPPYP00000004540 | ENSPPYP00000007706 | Cbl proto-oncogene. | RPS27A isoform 1. | 0.631 |
| CBL | CR201_G0053435 | ENSPPYP00000004540 | ENSPPYP00000002230 | Cbl proto-oncogene. | UBB isoform 1. | 0.682 |
| CBL | ENSPPYP00000008980 | ENSPPYP00000004540 | ENSPPYP00000008980 | Cbl proto-oncogene. | annotation not available | 0.477 |
| CBL | ENSPPYP00000009931 | ENSPPYP00000004540 | ENSPPYP00000009931 | Cbl proto-oncogene. | annotation not available | 0.555 |
| CBL | ENSPPYP00000022487 | ENSPPYP00000004540 | ENSPPYP00000022487 | Cbl proto-oncogene. | annotation not available | 0.477 |
| CBL | ENSPPYP00000023500 | ENSPPYP00000004540 | ENSPPYP00000023500 | Cbl proto-oncogene. | annotation not available | 0.631 |
| CBL | ENSPPYP00000023562 | ENSPPYP00000004540 | ENSPPYP00000023562 | Cbl proto-oncogene. | annotation not available | 0.631 |
| CBL | NEDD4L | ENSPPYP00000004540 | ENSPPYP00000010317 | Cbl proto-oncogene. | E3 ubiquitin-protein ligase NEDD4-like; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF- beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation. Promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, KCNH2, EAAT1 or CLC5. Promotes ubiquitination and degradation of SGK1 and TNK2. Ubiquitinates BRAT1 and this ubiq [...] | 0.927 |
| CBL | NEDD8 | ENSPPYP00000004540 | ENSPPYP00000006472 | Cbl proto-oncogene. | Ubiquitin-like protein Nedd8. | 0.646 |
page 1 of 79