20 items (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HYAL1	Hyaluronidase. (418 aa)
	STAB2	STAB2 isoform 1. (2293 aa)
	CR201_G0026044	LYVE1 isoform 1. (193 aa)
	CR201_G0011084	CD44 isoform 1. (351 aa)
	CR201_G0030247	FAM149B1 isoform 1. (526 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
	ENSPPYP00000012969	annotation not available (155 aa)
	HYAL2	Hyaluronidase. (473 aa)
	CHP1	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...] (195 aa)
	CR201_G0055535	Uncharacterized protein. (141 aa)
	FAM149A	FAM149A isoform 2. (585 aa)
	APBB3	APBB3 isoform 14. (493 aa)
	HMMR	HMMR isoform 4. (725 aa)
	GUSB	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. (650 aa)
	CR201_G0051062	CLEC1A isoform 2. (557 aa)
	ENSPPYP00000022387	annotation not available (119 aa)
	DKFZp468F2419	Uncharacterized protein DKFZp468F2419. (75 aa)
	HEXB	Beta-hexosaminidase. (331 aa)
	ENSPPYP00000012966	annotation not available (46 aa)
	HEXA	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. (529 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBB3	CHP1	ENSPPYP00000017729	ENSPPYP00000007214	APBB3 isoform 14.	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	0.400
APBB3	CR201_G0011084	ENSPPYP00000017729	ENSPPYP00000003856	APBB3 isoform 14.	CD44 isoform 1.	0.528
APBB3	CR201_G0026044	ENSPPYP00000017729	ENSPPYP00000004003	APBB3 isoform 14.	LYVE1 isoform 1.	0.432
CHP1	APBB3	ENSPPYP00000007214	ENSPPYP00000017729	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	APBB3 isoform 14.	0.400
CHP1	CR201_G0026044	ENSPPYP00000007214	ENSPPYP00000004003	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	LYVE1 isoform 1.	0.443
CHP1	HMMR	ENSPPYP00000007214	ENSPPYP00000017928	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	HMMR isoform 4.	0.400
CHP1	HYAL2	ENSPPYP00000007214	ENSPPYP00000015492	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	Hyaluronidase.	0.446
CHP1	SLC9A1	ENSPPYP00000007214	ENSPPYP00000001928	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	0.974
CR201_G0011084	APBB3	ENSPPYP00000003856	ENSPPYP00000017729	CD44 isoform 1.	APBB3 isoform 14.	0.528
CR201_G0011084	CR201_G0026044	ENSPPYP00000003856	ENSPPYP00000004003	CD44 isoform 1.	LYVE1 isoform 1.	0.687
CR201_G0011084	HMMR	ENSPPYP00000003856	ENSPPYP00000017928	CD44 isoform 1.	HMMR isoform 4.	0.879
CR201_G0011084	HYAL1	ENSPPYP00000003856	ENSPPYP00000015493	CD44 isoform 1.	Hyaluronidase.	0.488
CR201_G0011084	HYAL2	ENSPPYP00000003856	ENSPPYP00000015492	CD44 isoform 1.	Hyaluronidase.	0.809
CR201_G0011084	SLC9A1	ENSPPYP00000003856	ENSPPYP00000001928	CD44 isoform 1.	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.	0.716
CR201_G0011084	STAB2	ENSPPYP00000003856	ENSPPYP00000005576	CD44 isoform 1.	STAB2 isoform 1.	0.712
CR201_G0026044	APBB3	ENSPPYP00000004003	ENSPPYP00000017729	LYVE1 isoform 1.	APBB3 isoform 14.	0.432
CR201_G0026044	CHP1	ENSPPYP00000004003	ENSPPYP00000007214	LYVE1 isoform 1.	Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane- type Na(+)/H(+) ex [...]	0.443
CR201_G0026044	CR201_G0011084	ENSPPYP00000004003	ENSPPYP00000003856	LYVE1 isoform 1.	CD44 isoform 1.	0.687
CR201_G0026044	HMMR	ENSPPYP00000004003	ENSPPYP00000017928	LYVE1 isoform 1.	HMMR isoform 4.	0.681
CR201_G0026044	HYAL2	ENSPPYP00000004003	ENSPPYP00000015492	LYVE1 isoform 1.	Hyaluronidase.	0.555