Your Input: | |||||
ENSPPYP00000022319 | annotation not available (162 aa) | ||||
PSMB7 | Proteasome subunit beta. (277 aa) | ||||
PSMD5 | PSMD5 isoform 8. (97 aa) | ||||
PTCH1 | PTCH1 isoform 7. (1429 aa) | ||||
GAS1 | Growth arrest specific 1. (347 aa) | ||||
PRKACG | Protein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa) | ||||
GLIS3 | GLIS family zinc finger 3. (930 aa) | ||||
VCP | Transitional endoplasmic reticulum ATPase isoform X1. (806 aa) | ||||
ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) | ||||
ENSPPYP00000020490 | annotation not available (78 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa) | ||||
CUL1 | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...] (776 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa) | ||||
PRKAR2B | PRKAR2B isoform 1. (390 aa) | ||||
PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) | ||||
ENSPPYP00000019816 | annotation not available (197 aa) | ||||
GLI3 | GLI3 isoform 3. (1580 aa) | ||||
PSMA2 | Proteasome subunit alpha type. (234 aa) | ||||
ADCY1 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (636 aa) | ||||
SMURF1 | E3 ubiquitin-protein ligase. (838 aa) | ||||
IQCE | IQCE isoform 1. (684 aa) | ||||
PSMB9 | Proteasome subunit beta. (218 aa) | ||||
PSMD13 | PSMD13 isoform 6. (376 aa) | ||||
CR201_G0038668 | FOPNL isoform 7. (72 aa) | ||||
ENSPPYP00000022487 | annotation not available (153 aa) | ||||
OFD1 | OFD1 isoform 3. (959 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
ARR3 | ARR3 isoform 3. (388 aa) | ||||
ENSPPYP00000023500 | annotation not available (140 aa) | ||||
PSMB1-2 | Proteasome subunit beta type-1. (241 aa) | ||||
PSMD7 | PSMD7 isoform 1. (324 aa) | ||||
ENSPPYP00000023561 | annotation not available (122 aa) | ||||
ENSPPYP00000023562 | annotation not available (156 aa) | ||||
ENSPPYP00000023569 | annotation not available (247 aa) | ||||
ENSPPYP00000023733 | annotation not available (177 aa) | ||||
LOC100457600 | Proteasome subunit beta type-5-like. (263 aa) | ||||
GAS8 | GAS8 isoform 3. (478 aa) | ||||
TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa) | ||||
PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) | ||||
PSMA6 | Proteasome endopeptidase complex. (167 aa) | ||||
PSMD4 | PSMD4 isoform 1. (384 aa) | ||||
PSMD3 | PSMD3 isoform 1. (536 aa) | ||||
PSMA5 | Proteasome subunit alpha type. (278 aa) | ||||
TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) | ||||
CCDC13 | Coiled-coil domain-containing protein 13. (715 aa) | ||||
PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (382 aa) | ||||
PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) | ||||
IFT57 | Intraflagellar transport 57. (429 aa) | ||||
BOC | BOC isoform 3. (1110 aa) | ||||
GSK3B | GSK3B isoform 2; Belongs to the protein kinase superfamily. (380 aa) | ||||
ADCY5 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1100 aa) | ||||
IFT122 | IFT122 isoform 10. (1102 aa) | ||||
PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) | ||||
CUL3 | CUL3 isoform 1; Belongs to the cullin family. (768 aa) | ||||
TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) | ||||
TTC21B | TTC21B isoform 1. (1211 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
SPOPL | Speckle type BTB/POZ protein like. (392 aa) | ||||
GLI2 | GLI2 isoform 1. (1521 aa) | ||||
ADAM17 | ADAM17 isoform 1. (725 aa) | ||||
WDR35 | WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa) | ||||
PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) | ||||
ADCY3 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1084 aa) | ||||
IFT172 | IFT172 isoform 1. (1728 aa) | ||||
ERLEC1 | Endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non- glycosylated proteins and glycoproteins (By similarity). (471 aa) | ||||
PSME4 | Proteasome activator subunit 4. (1843 aa) | ||||
THAP7 | THAP domain containing 7. (309 aa) | ||||
RBX1 | RBX1 isoform 1. (108 aa) | ||||
PSMA7 | Proteasome subunit alpha type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (248 aa) | ||||
TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) | ||||
GNAS | GNAS isoform 2. (1037 aa) | ||||
IFT52 | IFT52 isoform 1. (448 aa) | ||||
CNBD2 | Cyclic nucleotide binding domain containing 2. (572 aa) | ||||
ITCH | E3 ubiquitin-protein ligase. (849 aa) | ||||
PSMF1 | Proteasome inhibitor PI31 subunit; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28 (By similarity). (271 aa) | ||||
CR201_G0019691 | SEL1L2 isoform 6. (647 aa) | ||||
FUZ | Fuzzy planar cell polarity protein. (418 aa) | ||||
TULP2 | TULP2 isoform 2; Belongs to the TUB family. (308 aa) | ||||
NUMBL | NUMBL isoform 1. (418 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
PSMD8 | 26S proteasome non-ATPase regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S14 family. (350 aa) | ||||
PDCD2L | Programmed cell death protein 2-like. (358 aa) | ||||
UBA52 | UBA52 isoform 10. (128 aa) | ||||
PRKACA | Protein kinase cAMP-activated catalytic subunit alpha. (299 aa) | ||||
PSMA8 | Proteasome subunit alpha type. (256 aa) | ||||
TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) | ||||
PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. (381 aa) | ||||
SPOP | Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING- [...] (374 aa) | ||||
MKS1 | MKS1 isoform 7. (343 aa) | ||||
ENSPPYP00000009931 | annotation not available (76 aa) | ||||
CR201_G0021182 | NOTUM isoform 1. (370 aa) | ||||
P4HB | Protein disulfide-isomerase; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chape [...] (508 aa) | ||||
PSMD12 | 26S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit p55 family. (456 aa) | ||||
SMURF2 | E3 ubiquitin-protein ligase. (877 aa) | ||||
PSMC5 | PSMC5 isoform 2; Belongs to the AAA ATPase family. (406 aa) | ||||
PSMB3 | Proteasome subunit beta. (218 aa) | ||||
PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (254 aa) | ||||
PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) | ||||
ENSPPYP00000008980 | annotation not available (158 aa) | ||||
DERL2 | Derlin-2; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and misfolded glycoproteins. May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the [...] (239 aa) | ||||
PSMB6 | Proteasome subunit beta. (239 aa) | ||||
ARRB2 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] (321 aa) | ||||
TUBB3 | T0170152 isoform 1; Belongs to the tubulin family. (450 aa) | ||||
PSMB10 | Proteasome subunit beta. (256 aa) | ||||
RPGRIP1L | RPGRIP1L isoform 3. (1315 aa) | ||||
ADCY7 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa) | ||||
FOPNL | FOPNL isoform 6. (107 aa) | ||||
ADCY9 | ADCY9 isoform 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (570 aa) | ||||
IFT140 | Intraflagellar transport 140. (1462 aa) | ||||
PDIA2 | Protein disulfide-isomerase A2; Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins (By similarity); Belongs to the protein disulfide isomerase family. (521 aa) | ||||
CR201_G0003353 | RPS27A isoform 1. (155 aa) | ||||
PSMA4 | Proteasome subunit alpha type. (261 aa) | ||||
ULK3 | Unc-51 like kinase 3. (483 aa) | ||||
SPATA5L1 | SPATA5L1 isoform 1. (753 aa) | ||||
DISP2 | DISP2 isoform 1. (1401 aa) | ||||
SEL1L | SEL1L isoform 1. (738 aa) | ||||
NUMB | NUMB endocytic adaptor protein. (651 aa) | ||||
PSMA3 | Proteasome subunit alpha type. (255 aa) | ||||
PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) | ||||
ADCY4 | Adenylate cyclase type 4 isoform X1. (1077 aa) | ||||
PSME2 | Proteasome activator subunit 2. (239 aa) | ||||
PSME1 | Proteasome activator subunit 1. (249 aa) | ||||
PSMB11 | Proteasome subunit beta. (300 aa) | ||||
PSMB5 | Proteasome subunit beta type-5; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (263 aa) | ||||
DZIP1 | DZIP1 isoform 1. (754 aa) | ||||
GPC5 | GPC5 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (517 aa) | ||||
CSNK1A1L | Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa) | ||||
IFT88 | IFT88 isoform 2. (768 aa) | ||||
UBC | UBC isoform 2. (625 aa) | ||||
PSMD9 | PSMD9 isoform 1. (223 aa) | ||||
OS9 | OS9 isoform 1. (611 aa) | ||||
GLI1 | GLI family zinc finger 1. (1106 aa) | ||||
DHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa) | ||||
ADCY6 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1165 aa) | ||||
TULP3 | TULP3 isoform 2. (439 aa) | ||||
TEX52 | T0163828 isoform 1. (306 aa) | ||||
CDON | CDON isoform 2. (1112 aa) | ||||
CR201_G0025506 | DYNC2H1 isoform 3. (1794 aa) | ||||
ENSPPYP00000004367 | annotation not available (644 aa) | ||||
DYNC2H1 | DYNC2H1 isoform 2. (987 aa) | ||||
ENSPPYP00000004309 | annotation not available (437 aa) | ||||
ARRB1 | ARRB1 isoform 2. (473 aa) | ||||
TUB | Tubby-like protein; Belongs to the TUB family. (561 aa) | ||||
SCUBE2 | SCUBE2 isoform 2. (1073 aa) | ||||
PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (263 aa) | ||||
PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) | ||||
SYVN1 | SYVN1 isoform 3. (616 aa) | ||||
GRK2 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa) | ||||
ENSPPYP00000003414 | annotation not available (440 aa) | ||||
HHATL | Hedgehog acyltransferase like; Belongs to the membrane-bound acyltransferase family. (504 aa) | ||||
TTC21A | TTC21A isoform 3. (1317 aa) | ||||
DZIP1L | DAZ interacting zinc finger protein 1 like. (767 aa) | ||||
PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. (909 aa) | ||||
EVC | EVC isoform 1. (991 aa) | ||||
EVC2 | EVC2 isoform 2. (1265 aa) | ||||
SEL1L3 | SEL1L3 isoform 3. (1096 aa) | ||||
WDR19 | WDR19 isoform 1. (1273 aa) | ||||
THAP6 | THAP domain containing 6. (222 aa) | ||||
SPATA5 | SPATA5 isoform 1. (892 aa) | ||||
INTU | INTU isoform 1. (942 aa) | ||||
HHIP | HHIP isoform 1. (647 aa) | ||||
LRP2BP | LRP2BP isoform 1. (312 aa) | ||||
ADCY2 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1013 aa) | ||||
LOC100437628 | Oral-facial-digital syndrome 1 protein-like isoform X1. (1012 aa) | ||||
KIF3A | Kinesin-like protein KIF3A; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. (696 aa) | ||||
SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (163 aa) | ||||
DELE1 | DAP3 binding cell death enhancer 1. (515 aa) | ||||
CSNK1A1 | CSNK1A1 isoform 6; Belongs to the protein kinase superfamily. (365 aa) | ||||
TULP1 | Tubby-like protein; Belongs to the TUB family. (542 aa) | ||||
PSMB1 | Proteasome subunit beta. (241 aa) | ||||
PDCD2 | Programmed cell death 2. (344 aa) | ||||
PSMB8 | Proteasome subunit beta. (272 aa) | ||||
SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa) | ||||
BTRC | BTRC isoform 2. (605 aa) | ||||
CR201_G0053435 | UBB isoform 1. (128 aa) | ||||
DISP3 | Dispatched RND transporter family member 3. (1425 aa) | ||||
PSMB2 | Proteasome subunit beta. (201 aa) | ||||
GLIS1 | GLIS1 isoform 2. (740 aa) | ||||
ENSPPYP00000001487 | annotation not available (440 aa) | ||||
PRKACB | PRKACB isoform 9; Belongs to the protein kinase superfamily. (354 aa) | ||||
PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) | ||||
ADCY10 | Adenylate cyclase type 10; Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1394 aa) | ||||
GPR161 | G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (549 aa) | ||||
CDC73 | Cell division cycle 73. (531 aa) | ||||
HHAT | Hedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (493 aa) | ||||
DISP1 | Dispatched RND transporter family member 1. (1524 aa) |