STRINGSTRING
LRPPRC LRPPRC COX20 COX20 DESI2 DESI2 AKT3 AKT3 C1orf198 C1orf198 LAMTOR2 LAMTOR2 PRKAB2 PRKAB2 MOV10 MOV10 LAMTOR5 LAMTOR5 LOC100440996 LOC100440996 PRKAA2 PRKAA2 PRDX1 PRDX1 RRAGC RRAGC AGO3 AGO3 AGO1 AGO1 AGO4 AGO4 SESN2 SESN2 SFN SFN H6PD H6PD CR201_G0028223 CR201_G0028223 DDIT4 DDIT4 PTEN PTEN PRDX5 PRDX5 COX8A COX8A ENSPPYP00000003894 ENSPPYP00000003894 LAMTOR1 LAMTOR1 SESN3 SESN3 TIGAR TIGAR PRKAG1 PRKAG1 RHEBL1 RHEBL1 COX14 COX14 GLS2 GLS2 CR201_G0001249 CR201_G0001249 PRKAB1 PRKAB1 LOC103892145 LOC103892145 GATC GATC LOC100459812 LOC100459812 GPX2 GPX2 COX16 COX16 AKT1 AKT1 ENSPPYP00000007168 ENSPPYP00000007168 LOC100461926 LOC100461926 TSC2 TSC2 MLST8 MLST8 TXNDC11 TXNDC11 TNRC6A TNRC6A DKFZp459N0929 DKFZp459N0929 COX6A2 COX6A2 YWHAE YWHAE TP53 TP53 SCO1 SCO1 COX11 COX11 TACO1 TACO1 TNRC6C TNRC6C CR201_G0002531 CR201_G0002531 TRIR TRIR GPI GPI COX6B1 COX6B1 AKT2 AKT2 COX6B2 COX6B2 COX7A1 COX7A1 YWHAB YWHAB KIAA1671 KIAA1671 YWHAH YWHAH TNRC6B TNRC6B CR201_G0049135 CR201_G0049135 ENSPPYP00000013376 ENSPPYP00000013376 COX5B COX5B ENSPPYP00000013663 ENSPPYP00000013663 YWHAQ YWHAQ ENSPPYP00000014206 ENSPPYP00000014206 GLS GLS PRKAG3 PRKAG3 TXNRD3 TXNRD3 NME9 NME9 TP63 TP63 COX7B2 COX7B2 COX18 COX18 ENSPPYP00000016598 ENSPPYP00000016598 LAMTOR3 LAMTOR3 DDIT4L DDIT4L PRKAA1 PRKAA1 SLC38A9 SLC38A9 COX7C COX7C ENSPPYP00000018466 ENSPPYP00000018466 COX7A2 COX7A2 RRAGD RRAGD SESN1 SESN1 LOC100436899 LOC100436899 COX19 COX19 LAMTOR4 LAMTOR4 YWHAG YWHAG ENSPPYP00000019656 ENSPPYP00000019656 NME8 NME8 NPVF NPVF CYCS CYCS NDUFA4 NDUFA4 CRYGN CRYGN RHEB RHEB PRKAG2 PRKAG2 GSR GSR COX6C COX6C YWHAZ YWHAZ RRM2B RRM2B AGO2 AGO2 RRAGA RRAGA ENSPPYP00000021735 ENSPPYP00000021735 TXN TXN TXNDC8 TXNDC8 TSC1 TSC1 SURF1 SURF1 ENSPPYP00000022312 ENSPPYP00000022312 RRAGB RRAGB ENSPPYP00000022918 ENSPPYP00000022918 COX7B COX7B ENSPPYP00000023003 ENSPPYP00000023003 G6PD G6PD COX1 COX1 COX2 COX2 COX3 COX3 CR201_G0036777 CR201_G0036777 ENSPPYP00000023629 ENSPPYP00000023629 DESI1 DESI1 PRDX2 PRDX2 ENSPPYP00000024179 ENSPPYP00000024179 RPTOR RPTOR COX4I2 COX4I2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRPPRCLRPPRC isoform 5. (803 aa)
COX20Cytochrome c oxidase assembly factor COX20. (118 aa)
DESI2Deubiquitinase DESI2; Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Belongs to the DeSI family. (180 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
C1orf198Chromosome 1 open reading frame 198. (327 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
MOV10MOV10 isoform 1. (1003 aa)
LAMTOR5LAMTOR5 isoform 1. (182 aa)
LOC100440996NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4. (81 aa)
PRKAA25'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] (552 aa)
PRDX1PRDX1 isoform 2. (199 aa)
RRAGCRRAGC isoform 1. (400 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
SESN2Sestrin-2; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. This stress-inducible metabolic regulator also plays a role in protection against oxidative and genotoxic stresses. May negatively regulate protein translation in response to endoplasmic reticulum stress, via TORC1. May positively regulate the transcripti [...] (480 aa)
SFNSFN isoform 1; Belongs to the 14-3-3 family. (248 aa)
H6PDH6PD isoform 2. (802 aa)
CR201_G0028223YWHAZ isoform 22. (245 aa)
DDIT4DNA damage inducible transcript 4. (232 aa)
PTENPongo abelii phosphatase and tensin homolog (PTEN), mRNA; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PRDX5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (344 aa)
COX8AT0108974 isoform 1. (69 aa)
ENSPPYP00000003894annotation not available (104 aa)
LAMTOR1Ragulator complex protein LAMTOR1; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. LAMTOR1 is directly responsible for anchoring the Ragulat [...] (161 aa)
SESN3SESN3 isoform 1. (491 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (271 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
RHEBL1RHEBL1 isoform 2. (183 aa)
COX14Cytochrome c oxidase assembly factor COX14. (57 aa)
GLS2GLS2 isoform 5. (602 aa)
CR201_G0001249TXNRD1 isoform 17. (277 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...] (270 aa)
LOC103892145Cytochrome c oxidase subunit 6A1, mitochondrial. (109 aa)
GATCGlutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatC family. (136 aa)
LOC100459812COX5A isoform 4. (150 aa)
GPX2GPX2 isoform 4. (150 aa)
COX16Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family. (85 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa)
ENSPPYP00000007168annotation not available (75 aa)
LOC100461926COX5A isoform 1. (150 aa)
TSC2TSC2 isoform 1. (1738 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
TXNDC11Thioredoxin domain containing 11. (960 aa)
TNRC6ATNRC6A isoform 4. (1958 aa)
DKFZp459N0929COX4I1 isoform 1. (116 aa)
COX6A2Cytochrome c oxidase subunit 6A2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...] (97 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
SCO1SCO cytochrome c oxidase assembly protein 1. (301 aa)
COX11Cytochrome c oxidase assembly protein COX11, mitochondrial; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. (287 aa)
TACO1TACO1 isoform 1. (293 aa)
TNRC6CTNRC6C isoform 1. (1961 aa)
CR201_G0002531TXNDC2 isoform 4. (478 aa)
TRIRTelomerase RNA component interacting RNase. (176 aa)
GPIGlucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). (558 aa)
COX6B1Cytochrome c oxidase subunit 6B1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and [...] (50 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
COX6B2Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (88 aa)
COX7A1Cytochrome c oxidase subunit 7A1. (79 aa)
YWHAB14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...] (262 aa)
KIAA1671KIAA1671 isoform 2. (1805 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
TNRC6BTNRC6B isoform 1. (1723 aa)
CR201_G0049135COX6B1 isoform 4. (108 aa)
ENSPPYP00000013376annotation not available (197 aa)
COX5BCytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (181 aa)
ENSPPYP00000013663annotation not available (38 aa)
YWHAQ14-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity). (245 aa)
ENSPPYP00000014206annotation not available (100 aa)
GLSGLS isoform 1. (669 aa)
PRKAG3PRKAG3 isoform 1. (489 aa)
TXNRD3TXNRD3 isoform 1. (569 aa)
NME9NME9 isoform 1; Belongs to the NDK family. (263 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
COX7B2Cytochrome c oxidase subunit 7B2. (81 aa)
COX18Cytochrome c oxidase assembly protein COX18, mitochondrial; Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT- CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT- CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase). (334 aa)
ENSPPYP00000016598annotation not available (104 aa)
LAMTOR3Ragulator complex protein LAMTOR3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP k [...] (124 aa)
DDIT4LDNA damage-inducible transcript 4-like protein; Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Belongs to the DDIT4 family. (193 aa)
PRKAA15'-AMP-activated protein kinase catalytic subunit alpha-1; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] (559 aa)
SLC38A9SLC38A9 isoform 14. (541 aa)
COX7CCOX7C isoform 1. (63 aa)
ENSPPYP00000018466Cytochrome c-like. (105 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (115 aa)
RRAGDRRAGD isoform 1. (333 aa)
SESN1SESN1 isoform 1. (551 aa)
LOC100436899Cytochrome c oxidase assembly protein COX11, mitochondrial-like. (276 aa)
COX19Cytochrome c oxidase assembly factor COX19. (90 aa)
LAMTOR4Ragulator complex protein LAMTOR4, N-terminally processed; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V- ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). (99 aa)
YWHAG14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. (247 aa)
ENSPPYP00000019656annotation not available (239 aa)
NME8NME8 isoform 1. (588 aa)
NPVFNeuropeptide VF precursor. (196 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (105 aa)
NDUFA4NDUFA4 isoform 1. (81 aa)
CRYGNCRYGN isoform 3; Belongs to the beta/gamma-crystallin family. (178 aa)
RHEBRHEB isoform 1. (167 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (531 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (472 aa)
COX6CCOX6C isoform 10. (75 aa)
YWHAZ14-3-3 protein zeta/delta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (By similarity). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity); Belongs to the 14-3-3 family. (245 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B; Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity). Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa)
AGO2Eukaryotic translation initiation factor 2C. (456 aa)
RRAGARas related GTP binding A. (313 aa)
ENSPPYP00000021735Cytochrome c-like. (38 aa)
TXNThioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] (220 aa)
TXNDC8TXNDC8 isoform 3. (115 aa)
TSC1TSC1 isoform 8. (1157 aa)
SURF1SURF1-like protein; Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. Belongs to the SURF1 family. (305 aa)
ENSPPYP00000022312annotation not available (75 aa)
RRAGBRas related GTP binding B. (346 aa)
ENSPPYP00000022918annotation not available (235 aa)
COX7BCytochrome c oxidase subunit 7B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (80 aa)
ENSPPYP00000023003annotation not available (72 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (543 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (514 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (227 aa)
COX3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (261 aa)
CR201_G0036777COX4I1 isoform 7. (91 aa)
ENSPPYP00000023629annotation not available (369 aa)
DESI1DESI1 isoform 1. (242 aa)
PRDX2Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2); Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (198 aa)
ENSPPYP0000002417914-3-3 protein epsilon-like isoform X1. (173 aa)
RPTORRPTOR isoform 4. (708 aa)
COX4I2Cytochrome c oxidase subunit 4I2. (171 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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