STRINGSTRING
NAA35 NAA35 COG2 COG2 STX6 STX6 VAMP4 VAMP4 VAMP3 VAMP3 USP6NL USP6NL VTI1A VTI1A CCDC186 CCDC186 VPS51 VPS51 ARFIP2 ARFIP2 RAB6A RAB6A M6PR M6PR ARL1 ARL1 COG6 COG6 COG3 COG3 NAA30 NAA30 COG7 COG7 NETO2 NETO2 COG8 COG8 COG4 COG4 VPS53 VPS53 CR201_G0048048 CR201_G0048048 STX8 STX8 NSF NSF COG1 COG1 NAPG NAPG PLIN3 PLIN3 STX10 STX10 SMIM7 SMIM7 NAPA NAPA NAPB NAPB STX16 STX16 ARFRP1 ARFRP1 GCC2 GCC2 VPS54 VPS54 TGOLN2 TGOLN2 TMF1 TMF1 EOGT EOGT GOLGA4 GOLGA4 RAB6B RAB6B SCOC SCOC ARFIP1 ARFIP1 RHOBTB3 RHOBTB3 IGF2R IGF2R VPS52 VPS52 COG5 COG5 GCC1 GCC1 RGP1 RGP1 RIC1 RIC1 CR201_G0043533 CR201_G0043533 RABEPK RABEPK RAB9B RAB9B NETO1 NETO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NAA35N-alpha-acetyltransferase 35, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells (By similarity). (725 aa)
COG2COG2 isoform 1. (738 aa)
STX6Syntaxin-6; Involved in intracellular vesicle trafficking. (255 aa)
VAMP4VAMP4 isoform 1. (134 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
USP6NLUSP6 N-terminal like. (827 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
CCDC186Coiled-coil domain-containing protein 186. (898 aa)
VPS51VPS51 isoform 3. (303 aa)
ARFIP2ARFIP2 isoform 2. (342 aa)
RAB6ARas-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER (By similarity); Belongs to the small GTPase superfamily. Rab family. (208 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (278 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (657 aa)
COG3COG3 isoform 1. (742 aa)
NAA30N(alpha)-acetyltransferase 30, NatC catalytic subunit. (361 aa)
COG7COG7 isoform 1. (771 aa)
NETO2NETO2 isoform 1. (525 aa)
COG8Conserved oligomeric Golgi complex subunit 8. (559 aa)
COG4Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. (785 aa)
VPS53Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] (770 aa)
CR201_G0048048NAA38 isoform 3. (67 aa)
STX8STX8 isoform 2. (236 aa)
NSFVesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. (816 aa)
COG1COG1 isoform 2. (980 aa)
NAPGNAPG isoform 3. (312 aa)
PLIN3Perilipin-3; Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. (434 aa)
STX10STX10 isoform 6; Belongs to the syntaxin family. (249 aa)
SMIM7T0132324 isoform 5. (75 aa)
NAPANAPA isoform 1. (276 aa)
NAPBNAPB isoform 4. (298 aa)
STX16STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa)
ARFRP1ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. (201 aa)
GCC2GCC2 isoform 3. (1686 aa)
VPS54VPS54 subunit of GARP complex. (977 aa)
TGOLN2TGOLN2 isoform 3. (369 aa)
TMF1TMF1 isoform 1. (992 aa)
EOGTEOGT isoform 1. (509 aa)
GOLGA4GOLGA4 isoform 1. (1931 aa)
RAB6BRAB6B, member RAS oncogene family. (208 aa)
SCOCShort coiled-coil protein. (159 aa)
ARFIP1ARFIP1 isoform 2. (373 aa)
RHOBTB3RHOBTB3 isoform 7. (548 aa)
IGF2RIGF2R isoform 1. (2446 aa)
VPS52VPS52 isoform 4. (723 aa)
COG5COG5 isoform 5. (859 aa)
GCC1GCC1 isoform 3. (658 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
RIC1RIC1 isoform 3. (1344 aa)
CR201_G0043533GOLGA1 isoform 5. (559 aa)
RABEPKRABEPK isoform 2. (363 aa)
RAB9BRas-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. (201 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (42%) [HD]