Your Input: | |
| | NETO2 | NETO2 isoform 1. (525 aa) |
| | DCTN5 | Dynactin subunit 5; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily. (182 aa) |
| | COG7 | COG7 isoform 1. (771 aa) |
| | CR201_G0054880 | CCDC78 isoform 5. (376 aa) |
| | MAN2A2 | Alpha-mannosidase. (1081 aa) |
| | KIF7 | KIF7 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (875 aa) |
| | TMED3 | Transmembrane p24 trafficking protein 3. (217 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (950 aa) |
| | KIF26A | KIF26A isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1090 aa) |
| | KLC1 | Kinesin light chain 1; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). (551 aa) |
| | GOLGA5 | GOLGA5 isoform 1. (731 aa) |
| | TRIP11 | TRIP11 isoform 2. (1979 aa) |
| | VIPAS39 | VIPAS39 isoform 6. (433 aa) |
| | ACTR10 | Actin related protein 10; Belongs to the actin family. (417 aa) |
| | NAA30 | N(alpha)-acetyltransferase 30, NatC catalytic subunit. (361 aa) |
| | COG3 | COG3 isoform 1. (742 aa) |
| | COG6 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function. (657 aa) |
| | ENSPPYP00000005898 | annotation not available (382 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | IGFLR1 | IGFLR1 isoform 1. (359 aa) |
| | PAFAH1B3 | Platelet-activating factor acetylhydrolase IB subunit gamma; Inactivates paf by removing the acetyl group at the sn-2 position. This is a catalytic subunit. Plays an important role during the development of brain (By similarity); Belongs to the 'GDSL' lipolytic enzyme family. Platelet- activating factor acetylhydrolase IB beta/gamma subunits subfamily. (231 aa) |
| | TMEM145 | TMEM145 isoform 3. (565 aa) |
| | KLC3 | Kinesin light chain 3; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport; Belongs to the kinesin light chain family. (504 aa) |
| | NAPA | NAPA isoform 1. (276 aa) |
| | KDELR1 | ER lumen protein-retaining receptor. (212 aa) |
| | CYTH2 | T0102787 isoform 1. (399 aa) |
| | ENSPPYP00000011873 | annotation not available (417 aa) |
| | CR201_G0019710 | KIF16B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1102 aa) |
| | NAPB | NAPB isoform 4. (298 aa) |
| | ATRN | ATRN isoform 2. (1378 aa) |
| | KIF3B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (695 aa) |
| | STX16 | STX16-NPEPL1 isoform 1; Belongs to the syntaxin family. (308 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) |
| | CR201_G0052180 | ARFGAP1 isoform 10. (324 aa) |
| | ARFRP1 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver. (201 aa) |
| | AGPAT3 | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma; Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor (By similarity). Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. Has a preference for arachidon [...] (376 aa) |
| | RAB36 | RAB36, member RAS oncogene family. (333 aa) |
| | CYTH4 | CYTH4 isoform 2. (394 aa) |
| | PLA2G6 | PLA2G6 isoform 1. (805 aa) |
| | KDELR3 | ER lumen protein-retaining receptor. (214 aa) |
| | ARFGAP3 | ADP-ribosylation factor GTPase-activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). (516 aa) |
| | SNAP29 | Synaptosomal-associated protein 29; SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions. (258 aa) |
| | ENSPPYP00000013420 | annotation not available (154 aa) |
| | GCC2 | GCC2 isoform 3. (1686 aa) |
| | CR201_G0003005 | T0009947 isoform 1. (1278 aa) |
| | RAB1A | RAB1A isoform 1. (205 aa) |
| | AFTPH | AFTPH isoform 3. (919 aa) |
| | VPS54 | VPS54 subunit of GARP complex. (977 aa) |
| | KIF3C | Kinesin-like protein KIF3C; Microtubule-based anterograde translocator for membranous organelles. (754 aa) |
| | NBAS | NBAS isoform 1. (2330 aa) |
| | TGOLN2 | TGOLN2 isoform 3. (369 aa) |
| | RAB3GAP1 | RAB3GAP1 isoform 3. (975 aa) |
| | ARL5A | ADP ribosylation factor like GTPase 5A; Belongs to the small GTPase superfamily. Arf family. (179 aa) |
| | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] (638 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | KIF1A | KIF1A isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1554 aa) |
| | ENSPPYP00000014962 | annotation not available (447 aa) |
| | COPG1 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (964 aa) |
| | TMF1 | TMF1 isoform 1. (992 aa) |
| | EOGT | EOGT isoform 1. (509 aa) |
| | ARF4 | ADP-ribosylation factor 4; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity); Belongs to the small GTPase superfamily. Arf family. (180 aa) |
| | KIF9 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (790 aa) |
| | KIF15 | Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1388 aa) |
| | GOLGA4 | GOLGA4 isoform 1. (1931 aa) |
| | DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa) |
| | ZCWPW2 | Zinc finger CW-type and PWWP domain containing 2. (356 aa) |
| | RAB6B | RAB6B, member RAS oncogene family. (208 aa) |
| | COPB2 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] (900 aa) |
| | ARL14 | ADP ribosylation factor like GTPase 14; Belongs to the small GTPase superfamily. Arf family. (192 aa) |
| | GOLIM4 | GOLIM4 isoform 3. (638 aa) |
| | ENSPPYP00000016227 | annotation not available (190 aa) |
| | STX18 | Syntaxin-18; Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. (338 aa) |
| | CR201_G0000620 | CENPE isoform 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1770 aa) |
| | RAB33B | Ras-related protein Rab-33B; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity). It is involved in autophagy, acting as a modulator of autophagosome formation (By similarity); Belongs to the small GTPase superfamily. Rab family. (229 aa) |
| | SCOC | Short coiled-coil protein. (159 aa) |
| | ARFIP1 | ARFIP1 isoform 2. (373 aa) |
| | FBXO8 | F-box protein 8. (319 aa) |
| | CFAP97 | Cilia- and flagella-associated protein 97; Belongs to the CFAP97 family. (530 aa) |
| | KIF2A | Kinesin-like protein KIF2A; Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity (By similarity). (660 aa) |
| | RHOBTB3 | RHOBTB3 isoform 7. (548 aa) |
| | MAN2A1 | Alpha-mannosidase. (1144 aa) |
| | KIF3A | Kinesin-like protein KIF3A; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. (696 aa) |
| | KIF20A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (817 aa) |
| | DCTN4 | Dynactin subunit 4; Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton (By similarity). (460 aa) |
| | BNIP1 | BCL2 interacting protein 1. (271 aa) |
| | FAM193B | FAM193B isoform 1. (814 aa) |
| | TUBB2B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | KIFC1 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (672 aa) |
| | KIF6 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (813 aa) |
| | KLC4 | KLC4 isoform 7. (636 aa) |
| | TUBE1 | Tubulin epsilon 1; Belongs to the tubulin family. (475 aa) |
| | MAN1A1 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (813 aa) |
| | IGF2R | IGF2R isoform 1. (2446 aa) |
| | KIF25 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (359 aa) |
| | VPS52 | VPS52 isoform 4. (723 aa) |
| | CYTH3 | CYTH3 isoform 1. (399 aa) |
| | KDELR2 | ER lumen protein-retaining receptor. (212 aa) |
| | ZCWPW1 | ZCWPW1 isoform 2. (608 aa) |
| | TMED4 | Transmembrane p24 trafficking protein 4. (227 aa) |
| | YKT6 | YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa) |
| | DYNC1I1 | Dynein cytoplasmic 1 intermediate chain 1. (645 aa) |
| | RINT1 | RINT1 isoform 1. (790 aa) |
| | COG5 | COG5 isoform 5. (859 aa) |
| | CAPZA2 | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa) |
| | GCC1 | GCC1 isoform 3. (658 aa) |
| | ARF5 | ADP-ribosylation factor 5. (130 aa) |
| | ENSPPYP00000020203 | annotation not available (122 aa) |
| | COPG2 | Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (726 aa) |
| | KIF13B | KIF13B isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1825 aa) |
| | DCTN6 | Dynactin subunit 6. (359 aa) |
| | KIFC2 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (831 aa) |
| | RGP1 | RGP1 homolog, RAB6A GEF complex partner 1. (391 aa) |
| | RIC1 | RIC1 isoform 3. (1344 aa) |
| | KIF27 | LOW QUALITY PROTEIN: kinesin-like protein KIF27. (1308 aa) |
| | ENSPPYP00000021665 | annotation not available (330 aa) |
| | NAA35 | N-alpha-acetyltransferase 35, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells (By similarity). (725 aa) |
| | BICD2 | BICD cargo adaptor 2. (824 aa) |
| | CR201_G0007992 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (615 aa) |
| | CR201_G0043533 | GOLGA1 isoform 5. (559 aa) |
| | RABEPK | RABEPK isoform 2. (363 aa) |
| | SURF4 | Surfeit locus protein 4; May play a role in the maintenance of the architecture of the endoplasmic reticulum-Golgi intermediate compartment and of the Golgi. Belongs to the SURF4 family. (254 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (388 aa) |
| | LOC100434822 | TUBA3C isoform 1. (450 aa) |
| | BET1L | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). (111 aa) |
| | DCTN3 | DCTN3 isoform 3. (186 aa) |
| | ENSPPYP00000022418 | annotation not available (435 aa) |
| | CXorf38 | Chromosome X open reading frame 38. (319 aa) |
| | KIF4A | KIF4A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (974 aa) |
| | RAB9B | Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network. (201 aa) |
| | ENSPPYP00000023221 | annotation not available (52 aa) |
| | SMIM10L2A | Small integral membrane protein 10 like 2A. (78 aa) |
| | CR201_G0054189-2 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | TMED9 | Transmembrane p24 trafficking protein 9. (235 aa) |
| | PAFAH1B2 | Platelet-activating factor acetylhydrolase IB subunit beta; Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit (By similarity); Belongs to the 'GDSL' lipolytic enzyme family. Platelet- activating factor acetylhydrolase IB beta/gamma subunits subfamily. (241 aa) |
| | KIF21B | KIF21B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1637 aa) |
| | ENSPPYP00000023866 | annotation not available (88 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa) |
| | TMED2 | Transmembrane p24 trafficking protein 2. (208 aa) |
| | TMED10 | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] (216 aa) |
| | NETO1 | Neuropilin and tolloid like 1. (533 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | ACTR1A | Actin related protein 1A. (376 aa) |
| | GBF1 | GBF1 isoform 1. (1855 aa) |
| | KIF11 | Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa) |
| | KIF20B | KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1734 aa) |
| | KIF5B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa) |
| | RAB18 | Ras-related protein Rab-18; Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration (By similarity). (206 aa) |
| | ARL5B | ADP ribosylation factor like GTPase 5B. (151 aa) |
| | USP6NL | USP6 N-terminal like. (827 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | CR201_G0054189 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa) |
| | VAMP3 | Vesicle associated membrane protein 3. (100 aa) |
| | KIF1B | KIF1B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1790 aa) |
| | CAPZB | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). (277 aa) |
| | MAN1C1 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (630 aa) |
| | KIF2C | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (706 aa) |
| | CAPZA1 | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. (286 aa) |
| | MAN1A2 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (641 aa) |
| | SEC22B | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. (215 aa) |
| | VPS45 | Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa) |
| | COPA | Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa) |
| | KIFAP3 | KIFAP3 isoform 2. (787 aa) |
| | VAMP4 | VAMP4 isoform 1. (134 aa) |
| | STX6 | Syntaxin-6; Involved in intracellular vesicle trafficking. (255 aa) |
| | PLA2G4A | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). (749 aa) |
| | RAB3GAP2 | RAB3GAP2 isoform 1. (1393 aa) |
| | ENSPPYP00000000154 | annotation not available (424 aa) |
| | ARF1 | ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | COG2 | COG2 isoform 1. (738 aa) |
| | LOC100452886 | TUBB8 isoform 7. (440 aa) |
| | ENSPPYP00000000046 | annotation not available (160 aa) |
| | KIF26B | KIF26B isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1702 aa) |
| | ARL1 | ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | KIF5A | Kinesin heavy chain isoform 5A; Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. [...] (1030 aa) |
| | DCTN2 | DCTN2 isoform 1. (401 aa) |
| | COPZ1 | Coatomer subunit zeta-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-disso [...] (177 aa) |
| | RACGAP1 | Rac GTPase activating protein 1. (632 aa) |
| | ARF3 | ADP-ribosylation factor 3; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). (181 aa) |
| | KIF21A | KIF21A isoform 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1674 aa) |
| | BICD1 | BICD1 isoform 4. (975 aa) |
| | CAPZA3 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | ARCN1 | Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also inf [...] (423 aa) |
| | ZW10 | Centromere/kinetochore protein zw10 homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (By similarity). (779 aa) |
| | RAB39A | RAB39A, member RAS oncogene family. (217 aa) |
| | ENSPPYP00000004309 | annotation not available (437 aa) |
| | RAB30 | RAB30, member RAS oncogene family. (203 aa) |
| | RAB6A | Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER (By similarity); Belongs to the small GTPase superfamily. Rab family. (208 aa) |
| | ARFIP2 | ARFIP2 isoform 2. (342 aa) |
| | COPB1 | Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also infl [...] (953 aa) |
| | KIF18A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (880 aa) |
| | ARFGAP2 | ADP-ribosylation factor GTPase-activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). (521 aa) |
| | STX5 | STX5 isoform 1; Belongs to the syntaxin family. (355 aa) |
| | VPS51 | VPS51 isoform 3. (303 aa) |
| | KLC2 | KLC2 isoform 1. (622 aa) |
| | RAB1B | Ras-related protein Rab-1B; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity). Regulates [...] (199 aa) |
| | ATRNL1 | ATRNL1 isoform 1. (1334 aa) |
| | CCDC186 | Coiled-coil domain-containing protein 186. (898 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (217 aa) |
| | COPE | Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex [...] (308 aa) |
| | USE1 | Unconventional SNARE in the endoplasmic reticulum protein 1. (259 aa) |
| | SMIM7 | T0132324 isoform 5. (75 aa) |
| | STX10 | STX10 isoform 6; Belongs to the syntaxin family. (249 aa) |
| | PLIN3 | Perilipin-3; Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. (434 aa) |
| | GALNT1 | Polypeptide N-acetylgalactosaminyltransferase. (559 aa) |
| | NAPG | NAPG isoform 3. (312 aa) |
| | ENSPPYP00000010091 | annotation not available (152 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | COPZ2 | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (175 aa) |
| | PRR15L | Proline rich 15 like. (103 aa) |
| | CYTH1 | CYTH1 isoform 4. (399 aa) |
| | KIF19 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (829 aa) |
| | COG1 | COG1 isoform 2. (980 aa) |
| | APPBP2 | Amyloid beta precursor protein binding protein 2. (585 aa) |
| | KIF18B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (409 aa) |
| | ENSPPYP00000009346 | annotation not available (387 aa) |
| | ENSPPYP00000009320 | ADP-ribosylation factor 2-like. (48 aa) |
| | NSF | Vesicle-fusing ATPase; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity); Belongs to the AAA ATPase family. (816 aa) |
| | GOSR2 | T0082108 isoform 1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa) |
| | KIF2B | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (674 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | GOSR1 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] (248 aa) |
| | CR201_G0053422 | TTC19 isoform 1. (434 aa) |
| | STX8 | STX8 isoform 2. (236 aa) |
| | CR201_G0048048 | NAA38 isoform 3. (67 aa) |
| | KIF1C | KIF1C isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1070 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | VPS53 | Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4- positive endosomes and promotes recycling of internalized t [...] (770 aa) |
| | KIF22 | Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA. Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (665 aa) |
| | TUBB3 | T0170152 isoform 1; Belongs to the tubulin family. (450 aa) |
| | COG4 | Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. (785 aa) |
| | COG8 | Conserved oligomeric Golgi complex subunit 8. (559 aa) |
| | DYNC1LI2 | Cytoplasmic dynein 1 light intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (465 aa) |
