Your Input: | |
| | CETN2 | CETN2 isoform 1. (172 aa) |
| | ENSPPYP00000023230 | annotation not available (111 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | CCNB3 | CCNB3 isoform 3; Belongs to the cyclin family. (1394 aa) |
| | OFD1 | OFD1 isoform 3. (959 aa) |
| | ENSPPYP00000022487 | annotation not available (153 aa) |
| | CR201_G0054793 | PPP2R3B isoform 2. (543 aa) |
| | ENSPPYP00000022418 | annotation not available (435 aa) |
| | CR201_G0038668 | FOPNL isoform 7. (72 aa) |
| | DCTN3 | DCTN3 isoform 3. (186 aa) |
| | PSMD13 | PSMD13 isoform 6. (376 aa) |
| | LOC100434822 | TUBA3C isoform 1. (450 aa) |
| | ENSPPYP00000022319 | annotation not available (162 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (388 aa) |
| | SSNA1 | SSNA1 isoform 2. (119 aa) |
| | ODF2 | Outer dense fiber protein 2; Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to th [...] (824 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | CNTRL | CNTRL isoform 3. (2183 aa) |
| | PSMD5 | PSMD5 isoform 8. (97 aa) |
| | CDK5RAP2 | CDK5RAP2 isoform 3. (1893 aa) |
| | CEP78 | CEP78 isoform 1. (678 aa) |
| | PPP1R16A | PPP1R16A isoform 5. (485 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | PCM1 | PCM1 isoform 1. (2042 aa) |
| | CUL1 | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...] (776 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | CEP41 | CEP41 isoform 2. (372 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | PSMA5 | Proteasome subunit alpha type. (278 aa) |
| | PSMD3 | PSMD3 isoform 1. (536 aa) |
| | PSMD4 | PSMD4 isoform 1. (384 aa) |
| | PSMA6 | Proteasome endopeptidase complex. (167 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | ENSPPYP00000024179 | 14-3-3 protein epsilon-like isoform X1. (173 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa) |
| | WDR41 | WDR41 isoform 3. (419 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa) |
| | CEP192 | CEP192 isoform 7. (1925 aa) |
| | CNTD2 | CNTD2 isoform 5; Belongs to the cyclin family. (201 aa) |
| | LIN37 | Protein lin-37 homolog isoform X1. (246 aa) |
| | ENSPPYP00000023866 | annotation not available (88 aa) |
| | LOC100457600 | Proteasome subunit beta type-5-like. (263 aa) |
| | ENSPPYP00000023569 | annotation not available (247 aa) |
| | ENSPPYP00000023562 | annotation not available (156 aa) |
| | ENSPPYP00000023561 | annotation not available (122 aa) |
| | PSMD7 | PSMD7 isoform 1. (324 aa) |
| | PSMB1-2 | Proteasome subunit beta type-1. (241 aa) |
| | ENSPPYP00000023500 | annotation not available (140 aa) |
| | SDCCAG8 | Serologically defined colon cancer antigen 8. (713 aa) |
| | LOC100452886 | TUBB8 isoform 7. (440 aa) |
| | ENSPPYP00000000154 | annotation not available (424 aa) |
| | LIN9 | LIN9 isoform 2. (692 aa) |
| | CENPF | CENPF isoform 1. (3113 aa) |
| | NEK2 | NIMA related kinase 2. (445 aa) |
| | PPP1R12B | Protein phosphatase 1 regulatory subunit. (1038 aa) |
| | ENSPPYP00000000624 | annotation not available (270 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PDE4DIP-2 | Myomegalin. (1386 aa) |
| | PDE4DIP | PDE4DIP isoform 7. (2553 aa) |
| | CR201_G0042150 | ODF2L isoform 6. (759 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | RBBP4 | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] (425 aa) |
| | CROCC | CROCC isoform 3. (1866 aa) |
| | ENSPPYP00000002111 | LOW QUALITY PROTEIN: rootletin-like. (210 aa) |
| | CR201_G0053435 | UBB isoform 1. (128 aa) |
| | CR201_G0025562 | CDK11B isoform 7. (775 aa) |
| | CR201_G0054189 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (442 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | OPTN | Optineurin; Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Negatively regulates the induction of IFNB in response to RNA virus infection. Plays a neuroprotective role in the eye and optic nerve. Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. May act by regulating membrane trafficking and cellular morphogenesis via a complex th [...] (532 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CENPA, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, G [...] (297 aa) |
| | BTRC | BTRC isoform 2. (605 aa) |
| | ACTR1A | Actin related protein 1A. (376 aa) |
| | TUBGCP2 | Gamma-tubulin complex component 2; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. (902 aa) |
| | ENSPPYP00000003414 | annotation not available (440 aa) |
| | FNBP4 | FNBP4 isoform 3. (1008 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa) |
| | CKAP5 | CKAP5 isoform 3. (2022 aa) |
| | PSMA1 | Proteasome subunit alpha type-1; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (263 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | PPME1 | Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme (By similarity); Belongs to the AB hydrolase superfamily. (386 aa) |
| | ENSPPYP00000004309 | annotation not available (437 aa) |
| | DEUP1 | Deuterosome assembly protein 1. (604 aa) |
| | CEP57 | Centrosomal protein 57. (499 aa) |
| | PPP2R1B | PPP2R1B isoform 5. (667 aa) |
| | CEP164 | CEP164 isoform 1. (1457 aa) |
| | FOXM1 | FOXM1 isoform 4. (763 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | DCTN2 | DCTN2 isoform 1. (401 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (957 aa) |
| | CEP290 | CEP290 isoform 4. (2481 aa) |
| | NEDD1 | NEDD1 isoform 1. (659 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | PSMD9 | PSMD9 isoform 1. (223 aa) |
| | UBC | UBC isoform 2. (625 aa) |
| | ENSPPYP00000005898 | annotation not available (382 aa) |
| | CENPJ | CENPJ isoform 2. (1290 aa) |
| | CCNA1 | CCNA1 isoform 3; Belongs to the cyclin family. (464 aa) |
| | MZT1 | Mitotic spindle organizing protein 1. (82 aa) |
| | BORA | BORA aurora kinase A activator. (619 aa) |
| | ENSPPYP00000006214 | annotation not available (312 aa) |
| | CR201_G0004139 | Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (610 aa) |
| | HAUS4 | T0115198 isoform 1. (436 aa) |
| | AJUBA | LIM domain-containing protein ajuba isoform X1. (538 aa) |
| | PSMB5 | Proteasome subunit beta type-5; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (263 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | PSME1 | Proteasome activator subunit 1. (249 aa) |
| | PSME2 | Proteasome activator subunit 2. (239 aa) |
| | PPP2R3C | PPP2R3C isoform 2. (402 aa) |
| | NIN | NIN isoform 1. (2132 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (288 aa) |
| | LIN52 | Protein lin-52 homolog. (116 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (873 aa) |
| | HSP90AA1 | HSP90AA1 isoform 6. (615 aa) |
| | TUBGCP5 | Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa) |
| | HAUS2 | HAUS augmin-like complex subunit 2; Belongs to the HAUS2 family. (235 aa) |
| | TUBGCP4 | Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (658 aa) |
| | CEP152 | CEP152 isoform 2. (1679 aa) |
| | CCNB2 | CCNB2 isoform 1; Belongs to the cyclin family. (398 aa) |
| | MYO1E | MYO1E isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1109 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | CR201_G0003353 | RPS27A isoform 1. (155 aa) |
| | PKMYT1 | PKMYT1 isoform 10; Belongs to the protein kinase superfamily. (499 aa) |
| | NDE1 | NDE1 isoform 1. (349 aa) |
| | FOPNL | FOPNL isoform 6. (107 aa) |
| | CCP110 | Centriolar coiled-coil protein 110. (1012 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (603 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (334 aa) |
| | PSMB10 | Proteasome subunit beta. (256 aa) |
| | CDK10 | Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (360 aa) |
| | TUBB3 | T0170152 isoform 1; Belongs to the tubulin family. (450 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | ENSPPYP00000008980 | annotation not available (158 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (254 aa) |
| | TUBG2 | Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa) |
| | PSMB3 | Proteasome subunit beta. (218 aa) |
| | PSMC5 | PSMC5 isoform 2; Belongs to the AAA ATPase family. (406 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit p55 family. (456 aa) |
| | CDK3 | CDK3 isoform 1; Belongs to the protein kinase superfamily. (305 aa) |
| | CR201_G0021599 | CEP131 isoform 2. (894 aa) |
| | PPP1R27 | PPP1R27 isoform 1. (122 aa) |
| | CSNK1D | Casein kinase I isoform delta; Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, dete [...] (404 aa) |
| | TUBD1 | TUBD1 isoform 13; Belongs to the tubulin family. (453 aa) |
| | ENSPPYP00000009931 | annotation not available (76 aa) |
| | CEP76 | Centrosomal protein of 76 kDa; Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity). (659 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa) |
| | MPPE1 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity); Belongs to the metallophosphoesterase superfamily. MPPE1 family. (396 aa) |
| | PPP4R1 | PPP4R1 isoform 1. (947 aa) |
| | PSMA8 | Proteasome subunit alpha type. (256 aa) |
| | MAPRE2 | Microtubule-associated protein RP/EB family member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity); Belongs to the MAPRE family. (327 aa) |
| | HAUS1 | HAUS augmin like complex subunit 1. (278 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa) |
| | MYO1F | MYO1F isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa) |
| | RAB8A | Ras-related protein Rab-8A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes t [...] (207 aa) |
| | HAUS8 | HAUS8 isoform 2. (410 aa) |
| | UBA52 | UBA52 isoform 10. (128 aa) |
| | HAUS5 | HAUS5 isoform 5. (584 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S14 family. (350 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | PPP2R1A | PPP2R1A isoform 7. (558 aa) |
| | ENSPPYP00000011659 | annotation not available (548 aa) |
| | ENSPPYP00000011873 | annotation not available (417 aa) |
| | ENSPPYP00000011927 | annotation not available (116 aa) |
| | ENSPPYP00000011942 | annotation not available (117 aa) |
| | NINL | NINL isoform 2. (1382 aa) |
| | CDC25B | Cell division cycle 25B. (580 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit; Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28 (By similarity). (271 aa) |
| | TPX2 | Targeting protein for Xklp2; Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation. TPX2 is inactivated upon binding to importin-alpha. At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin- alpha, allowing TPX2 to activate [...] (746 aa) |
| | MAPRE1 | Microtubule-associated protein RP/EB family member 1; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, a [...] (314 aa) |
| | CEP250 | CEP250 isoform 4. (2389 aa) |
| | PPP1R16B | PPP1R16B isoform 1. (519 aa) |
| | MYBL2 | MYBL2 isoform 1. (691 aa) |
| | AURKA | AURKA isoform 10; Belongs to the protein kinase superfamily. (404 aa) |
| | ENSPPYP00000012476 | annotation not available (955 aa) |
| | NPEPL1 | Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family. (411 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (452 aa) |
| | PSMA7 | Proteasome subunit alpha type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pr [...] (248 aa) |
| | TCP10L | T-complex protein 10A homolog 2 isoform X1. (214 aa) |
| | PCNT | PCNT isoform 1. (3265 aa) |
| | SFI1 | SFI1 isoform 9. (1202 aa) |
| | LOC100447547 | T0085674 isoform 1; Belongs to the protein kinase superfamily. (416 aa) |
| | RBX1 | RBX1 isoform 1. (108 aa) |
| | EP300 | EP300 isoform 1. (2380 aa) |
| | GTSE1 | G2 and S-phase expressed 1. (739 aa) |
| | TUBGCP6 | Tubulin gamma complex associated protein 6. (1739 aa) |
| | ENSPPYP00000013420 | annotation not available (154 aa) |
| | TSGA10 | TSGA10 isoform 2. (698 aa) |
| | CR201_G0003005 | T0009947 isoform 1. (1278 aa) |
| | ALMS1 | ALMS1 isoform 2. (4160 aa) |
| | XPO1 | XPO1 isoform 9. (1034 aa) |
| | PSME4 | Proteasome activator subunit 4. (1843 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (327 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (281 aa) |
| | CLASP1 | CLASP1 isoform 3. (1537 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and help dynein bind to dynactin 150 kDa component (By similarity). organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such a [...] (638 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | SPATA3 | SPATA3 isoform 1. (183 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | CR201_G0045389 | MZT2B isoform 4. (135 aa) |
| | MZT2B | Uncharacterized protein. (158 aa) |
| | ENSPPYP00000014962 | annotation not available (447 aa) |
| | ENSPPYP00000015333 | annotation not available (74 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | CEP63 | Centrosomal protein of 63 kDa; Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Also recruits CDK1 to centrosomes (By similarity). Plays a role in DNA damage response. Following DNA damage, such as double- strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression (By similarity). (541 aa) |
| | PPP2R3A | PPP2R3A isoform 2. (529 aa) |
| | CEP70 | Centrosomal protein of 70 kDa; Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle (By similarity). (597 aa) |
| | ENSPPYP00000016040 | LOW QUALITY PROTEIN: putative heat shock protein HSP 90-alpha A5. (166 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. (909 aa) |
| | HAUS3 | HAUS3 isoform 1. (428 aa) |
| | LAP3 | Leucine aminopeptidase 3. (519 aa) |
| | CEP135 | CEP135 isoform 2. (1140 aa) |
| | LIN54 | Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence-specific manner. Specifically recognizes the consensu [...] (749 aa) |
| | ENSPPYP00000016659 | annotation not available (592 aa) |
| | CCNA2 | CCNA2 isoform 1; Belongs to the cyclin family. (432 aa) |
| | PLK4 | Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit [...] (970 aa) |
| | ENSPPYP00000016980 | annotation not available (100 aa) |
| | ENSPPYP00000017056 | annotation not available (412 aa) |
| | ENSPPYP00000017058 | annotation not available (377 aa) |
| | ENSPPYP00000017062 | annotation not available (62 aa) |
| | CEP72 | CEP72 isoform 1. (641 aa) |
| | FBXL7 | F-box and leucine rich repeat protein 7. (444 aa) |
| | LOC100437628 | Oral-facial-digital syndrome 1 protein-like isoform X1. (1012 aa) |
| | CCNB1 | CCNB1 isoform 1; Belongs to the cyclin family. (433 aa) |
| | CDK7 | CDK7 isoform 1; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNH | CCNH isoform 4; Belongs to the cyclin family. (323 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (163 aa) |
| | CDC25C | Cell division cycle 25C. (473 aa) |
| | APBB3 | APBB3 isoform 14. (493 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (583 aa) |
| | HMMR | HMMR isoform 4. (725 aa) |
| | FBXW11 | FBXW11 isoform 1. (489 aa) |
| | FAM193B | FAM193B isoform 1. (814 aa) |
| | TUBB2B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | TUBB | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). Belongs to the tubulin family. (444 aa) |
| | FKBPL | FKBP prolyl isomerase like. (349 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | HSP90AB1 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (724 aa) |
| | TUBE1 | Tubulin epsilon 1; Belongs to the tubulin family. (475 aa) |
| | CR201_G0044827 | TCP10L2 isoform 1. (353 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMB8 | Proteasome subunit beta. (272 aa) |
| | PSMB9 | Proteasome subunit beta. (218 aa) |
| | FBXL18 | F-box and leucine rich repeat protein 18. (718 aa) |
| | YWHAG | 14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family. (247 aa) |
| | ENSPPYP00000019656 | annotation not available (239 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | ENSPPYP00000019816 | annotation not available (197 aa) |
| | AKAP9 | AKAP9 isoform 1. (3770 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (433 aa) |
| | PRKAR2B | PRKAR2B isoform 1. (390 aa) |
| | CR201_G0054189-2 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa) |
| | HAUS7 | HAUS augmin-like complex subunit 7 isoform X1. (394 aa) |
