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| | BCL10 | BCL10 isoform 1. (263 aa) |
| | UBE2T | Ubiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (197 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | PEX14 | PEX14 isoform 2. (373 aa) |
| | CR201_G0053435 | UBB isoform 1. (128 aa) |
| | PEX10 | PEX10 isoform 2. (326 aa) |
| | UBE2J2 | Ubiquitin conjugating enzyme E2 J2. (259 aa) |
| | WAC | WW domain containing adaptor with coiled-coil. (647 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | SLC39A13 | Zinc transporter ZIP13; Acts as a zinc-influx transporter. (369 aa) |
| | CTR9 | CTR9 isoform 1. (1173 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase 5; Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys- 48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity (By similarity). (840 aa) |
| | PEX5 | Peroxisomal biogenesis factor 5. (556 aa) |
| | PRPF40B | Pre-mRNA processing factor 40 homolog B. (892 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2 N; The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly- ubiquitination of [...] (152 aa) |
| | UBC | UBC isoform 2. (625 aa) |
| | UBE2L5 | Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa) |
| | UCHL3 | Ubiquitin carboxyl-terminal hydrolase. (144 aa) |
| | ZC2HC1C | Zinc finger C2HC domain-containing protein 1C homolog; Belongs to the ZC2HC1 family. (533 aa) |
| | CINP | Cyclin dependent kinase 2 interacting protein. (212 aa) |
| | RTF1 | RNA polymerase-associated protein RTF1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription [...] (710 aa) |
| | LEO1 | RNA polymerase-associated protein LEO1; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox [...] (666 aa) |
| | CR201_G0049226 | UBE2Q2 isoform 2. (210 aa) |
| | WDR61 | WD repeat domain 61. (305 aa) |
| | CR201_G0003353 | RPS27A isoform 1. (155 aa) |
| | SELENOS | SELENOS isoform 1. (188 aa) |
| | USP7 | USP7 isoform 8; Belongs to the peptidase C19 family. (1082 aa) |
| | RNF40 | E3 ubiquitin-protein ligase BRE1B; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] (1001 aa) |
| | AKTIP | AKT-interacting protein; Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade (By similarity). (293 aa) |
| | UBE2G1 | Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (170 aa) |
| | ENSPPYP00000008980 | annotation not available (158 aa) |
| | PEX12 | Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (359 aa) |
| | ENSPPYP00000009931 | annotation not available (76 aa) |
| | CR201_G0012323 | UBE2Z isoform 1. (215 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | CDC34 | CDC34 isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (217 aa) |
| | UBA52 | UBA52 isoform 10. (128 aa) |
| | PAF1 | RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser- 5'-phosphorylated forms and is involved in transcriptional elongation, acting both indepentently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription [...] (533 aa) |
| | CNFN | CNFN isoform 1. (40 aa) |
| | UBE2S | UBE2S isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (222 aa) |
| | ENSPPYP00000011752 | annotation not available (89 aa) |
| | ENSPPYP00000012057 | annotation not available (147 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | UBE2G2 | Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). (165 aa) |
| | UBE2L3 | Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the [...] (154 aa) |
| | RNF181 | Ring finger protein 181. (153 aa) |
| | PEX13 | Peroxisomal biogenesis factor 13. (403 aa) |
| | YIPF4 | Protein YIPF. (244 aa) |
| | RNF144A | RBR-type E3 ubiquitin transferase. (292 aa) |
| | UBE2E3 | Ubiquitin conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (207 aa) |
| | ENSPPYP00000015128 | Histone H2B type 1-K-like. (129 aa) |
| | RAD18 | RAD18 isoform 2. (495 aa) |
| | UBE2E1 | Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | HLTF | HLTF isoform 1. (1063 aa) |
| | PEX5L | PEX5L isoform 2. (625 aa) |
| | TMEM129 | Transmembrane protein 129. (362 aa) |
| | UBE2K | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa) |
| | UBA6 | UBA6 isoform 1. (1052 aa) |
| | UBE2D3 | Ubiquitin-conjugating enzyme E2 D3; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Ubiquitin chain elongation is then performed by CDC34, building ubiquitin chains from the UBE2D3-primed [...] (149 aa) |
| | OTULINL | FAM105A isoform 1. (360 aa) |
| | OTULIN | OTU deubiquitinase with linear linkage specificity. (352 aa) |
| | UBE2B | Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | YIPF5 | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi. (257 aa) |
| | H2BC1 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | H2BC3 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC100439336 | Histone H2B type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | H2BC5 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC100439336-2 | Histone H2B type 1. (126 aa) |
| | LOC100439336-3 | Histone H2B type 1. (126 aa) |
| | H2BC9 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC100445948 | Histone H2B type 1-like. (128 aa) |
| | LOC100455882 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BC13 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | H2BC14 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC100432873 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | HLA-A | Popy Class I histocompatibility antigen, A-1 alpha chain. (365 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1683 aa) |
| | UBE2H | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa) |
| | ENSPPYP00000020474 | annotation not available (97 aa) |
| | PRKDC | PRKDC isoform 1; Belongs to the PI3/PI4-kinase family. (3972 aa) |
| | UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2; Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly- ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (By similarity); Belongs to the ubiquitin-c [...] (145 aa) |
| | PEX2 | PEX2 isoform 1. (305 aa) |
| | DERL1 | Derlin-1; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the misfolded protein. Also involved in endoplasmic reticulum stress-induced pre- emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for pro [...] (201 aa) |
| | VCP | Transitional endoplasmic reticulum ATPase isoform X1. (806 aa) |
| | UBE2R2 | Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) |
| | RRAGA | Ras related GTP binding A. (313 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | ENSPPYP00000022487 | annotation not available (153 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa) |
| | UBA1 | UBA1 isoform 1; Belongs to the ubiquitin-activating E1 family. (1056 aa) |
| | ENSPPYP00000022962 | annotation not available (77 aa) |
| | ENSPPYP00000023048 | annotation not available (124 aa) |
| | UBE2A | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | UBE2NL | Ubiquitin conjugating enzyme E2 N like (gene/pseudogene). (152 aa) |
| | H2BW1 | H2BFWT isoform 1; Belongs to the histone H2B family. (177 aa) |
| | CR201_G0020495 | H2BFM isoform 1; Belongs to the histone H2B family. (253 aa) |
| | ENSPPYP00000023500 | annotation not available (140 aa) |
| | ENSPPYP00000023562 | annotation not available (156 aa) |
| | CR201_G0020693 | T0070593 isoform 1. (151 aa) |
