STRINGSTRING
PTCHD1 PTCHD1 PRKACB PRKACB PTCHD3 PTCHD3 APOA1 APOA1 A2ML1 A2ML1 A2M A2M PZP PZP CR201_G0036407 CR201_G0036407 CR201_G0037814 CR201_G0037814 ZDHHC8 ZDHHC8 ZDHHC19 ZDHHC19 CR201_G0050222 CR201_G0050222 SMPDL3A SMPDL3A PRKACG PRKACG ABCA1 ABCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTCHD1Patched domain containing 1. (888 aa)
PRKACBPRKACB isoform 9; Belongs to the protein kinase superfamily. (354 aa)
PTCHD3PTCHD3 isoform 1. (695 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (By similarity). (219 aa)
A2ML1A2ML1 isoform 1. (1277 aa)
A2MAlpha-2-macroglobulin; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the co [...] (1474 aa)
PZPPZP alpha-2-macroglobulin like. (1483 aa)
CR201_G0036407T0128421 isoform 2. (94 aa)
CR201_G0037814PLEKHD1 isoform 1. (434 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (715 aa)
ZDHHC19Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (309 aa)
CR201_G0050222PTCHD4 isoform 2. (241 aa)
SMPDL3AAcid sphingomyelinase-like phosphodiesterase. (404 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (351 aa)
ABCA1ABCA1 isoform 1. (2234 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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