Your Input: | |
| | GLRX3 | GLRX3 isoform 1. (335 aa) |
| | RRP12 | RRP12 isoform 4. (1273 aa) |
| | CR201_G0053435 | UBB isoform 1. (128 aa) |
| | ATP6V0B | ATP6V0B isoform 3; Belongs to the V-ATPase proteolipid subunit family. (156 aa) |
| | CELF3 | CELF3 isoform 4. (396 aa) |
| | MR1 | Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity). (340 aa) |
| | ATP6V1G3 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | FLVCR1 | Feline leukemia virus subgroup C cellular receptor 1. (555 aa) |
| | ENSPPYP00000000132 | annotation not available (136 aa) |
| | CNST | CNST isoform 1. (690 aa) |
| | ATP6AP1L | ATPase H+ transporting accessory protein 1 like. (224 aa) |
| | FTMT | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (242 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (163 aa) |
| | SLC22A23 | SLC22A23 isoform 2. (538 aa) |
| | ENSPPYP00000018104 | annotation not available (312 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (348 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | TFR2 | TFR2 isoform 2. (801 aa) |
| | STEAP2 | STEAP2 isoform 3. (479 aa) |
| | STEAP4 | STEAP4 metalloreductase. (459 aa) |
| | ATP6V1F | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (876 aa) |
| | FTL | Ferritin light chain; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity); Belongs to the ferritin family. (189 aa) |
| | UBA52 | UBA52 isoform 10. (128 aa) |
| | CELF5 | CELF5 isoform 1. (197 aa) |
| | CELF4 | CUGBP Elav-like family member 4; RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre- mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic site [...] (458 aa) |
| | MPPE1 | Metallophosphoesterase 1; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins (By similarity); Belongs to the metallophosphoesterase superfamily. MPPE1 family. (396 aa) |
| | ENSPPYP00000009931 | annotation not available (76 aa) |
| | CYB561 | Cytochrome b561; Secretory vesicle-specific electron transport protein. (251 aa) |
| | ATP6V0A1 | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). (862 aa) |
| | SLC46A1 | SLC46A1 isoform 1. (459 aa) |
| | ENSPPYP00000008980 | annotation not available (158 aa) |
| | SLC22A31 | SLC22A31 isoform 1. (352 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the acti [...] (351 aa) |
| | HMOX2 | HMOX2 isoform 7. (404 aa) |
| | ATP6V0C | V-type H+-transporting ATPase 16kDa proteolipid subunit. (128 aa) |
| | CR201_G0003353 | RPS27A isoform 1. (155 aa) |
| | IREB2 | IREB2 isoform 4; Belongs to the aconitase/IPM isomerase family. (565 aa) |
| | CR201_G0028730 | T0099608 isoform 1. (428 aa) |
| | FLVCR2 | Feline leukemia virus subgroup C cellular receptor family member 2. (526 aa) |
| | CUL1 | Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...] (776 aa) |
| | ENSPPYP00000020370 | annotation not available (177 aa) |
| | ATP6V1B2 | V-type proton ATPase subunit B, brain isoform. (278 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (465 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C 1; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (382 aa) |
| | ACO1 | ACO1 isoform 1; Belongs to the aconitase/IPM isomerase family. (931 aa) |
| | LCN2 | LCN2 isoform 1; Belongs to the calycin superfamily. Lipocalin family. (333 aa) |
| | ENSPPYP00000022319 | annotation not available (162 aa) |
| | ENSPPYP00000022487 | annotation not available (153 aa) |
| | FTHL17 | Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa) |
| | ENSPPYP00000022645 | Ferritin heavy chain-like. (183 aa) |
| | HEPH | HEPH isoform 1; Belongs to the multicopper oxidase family. (1137 aa) |
| | ATP6AP1 | ATPase H+ transporting accessory protein 1. (475 aa) |
| | ENSPPYP00000023462 | Ferritin heavy chain. (188 aa) |
| | ATP6V1G1 | V-type H+-transporting ATPase subunit G. (115 aa) |
| | ENSPPYP00000023500 | annotation not available (140 aa) |
| | ENSPPYP00000023562 | annotation not available (156 aa) |
| | CAND2 | CAND2 isoform 2. (1220 aa) |
| | ATP6V0E1 | V-type proton ATPase subunit e 1; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa) |
| | STEAP3 | STEAP3 metalloreductase. (488 aa) |
| | SLC11A2 | SLC11A2 isoform 12. (573 aa) |
| | ENSPPYP00000024559 | annotation not available (71 aa) |
| | ENSPPYP00000024651 | annotation not available (188 aa) |
| | ATP6V1D | V-type proton ATPase subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). (247 aa) |
| | NEDD8 | Ubiquitin-like protein Nedd8. (81 aa) |
| | SLC22A17 | SLC22A17 isoform 5. (593 aa) |
| | SLC46A3 | Solute carrier family 46 member 3. (463 aa) |
| | LIM2 | Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (215 aa) |
| | UBC | UBC isoform 2. (625 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa) |
| | CAND1 | Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar [...] (1230 aa) |
| | HEPHL1 | HEPHL1 isoform 1; Belongs to the multicopper oxidase family. (767 aa) |
| | CYB561A3 | Cytochrome b561 family member A3. (242 aa) |
| | FTH1 | Ferritin heavy chain, N-terminally processed; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. (183 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (559 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (760 aa) |
| | SLC49A3 | MFSD7 isoform 1. (526 aa) |
| | FBXL5 | F-box/LRR-repeat protein 5; Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued (By similarity). (664 aa) |
| | ABCG2 | ABCG2 isoform 2. (625 aa) |
| | ENSPPYP00000017156 | annotation not available (234 aa) |
| | CP | Ceruloplasmin; Belongs to the multicopper oxidase family. (1065 aa) |
| | TF | TF isoform 1; Belongs to the transferrin family. (703 aa) |
| | CR201_G0007982 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | ATP6V1A | V-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity. Belongs to the ATPase alpha/beta chains family. (578 aa) |
| | SLC49A4 | Solute carrier family 49 member 4. (478 aa) |
| | SLC40A1 | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (572 aa) |
| | CYBRD1 | Cytochrome b reductase 1; Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells (By similarity). (286 aa) |
| | ATP6V1C2 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (389 aa) |
| | ATP6V1E2 | ATPase H+ transporting V1 subunit E2. (226 aa) |
| | ATP6V1B1 | V-type proton ATPase subunit B, brain isoform; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). (509 aa) |
| | HMOX1 | Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. (288 aa) |
| | ATP6V1E1 | ATP6V1E1 isoform 1. (203 aa) |
