14 items (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CR201_G0053435	UBB isoform 1. (128 aa)
	ENSPPYP00000023562	annotation not available (156 aa)
	ENSPPYP00000023500	annotation not available (140 aa)
	ENSPPYP00000022319	annotation not available (162 aa)
	CUL1	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...] (776 aa)
	MAFK	MAF bZIP transcription factor K. (156 aa)
	BACH2	BACH2 isoform 1. (841 aa)
	SKP1	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...] (163 aa)
	FBXL17	FBXL17 isoform 1. (751 aa)
	SKP2	SKP2 isoform 1. (410 aa)
	RBX1	RBX1 isoform 1. (108 aa)
	BACH1	BACH1 isoform 5. (736 aa)
	CR201_G0003353	RPS27A isoform 1. (155 aa)
	UBC	UBC isoform 2. (625 aa)

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BACH1	CUL1	ENSPPYP00000012646	ENSPPYP00000020352	BACH1 isoform 5.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.513
BACH1	ENSPPYP00000022319	ENSPPYP00000012646	ENSPPYP00000022319	BACH1 isoform 5.	annotation not available	0.434
BACH1	FBXL17	ENSPPYP00000012646	ENSPPYP00000017523	BACH1 isoform 5.	FBXL17 isoform 1.	0.973
BACH1	MAFK	ENSPPYP00000012646	ENSPPYP00000019390	BACH1 isoform 5.	MAF bZIP transcription factor K.	0.988
BACH1	RBX1	ENSPPYP00000012646	ENSPPYP00000013235	BACH1 isoform 5.	RBX1 isoform 1.	0.584
BACH1	SKP1	ENSPPYP00000012646	ENSPPYP00000017649	BACH1 isoform 5.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...]	0.434
BACH1	UBC	ENSPPYP00000012646	ENSPPYP00000005811	BACH1 isoform 5.	UBC isoform 2.	0.500
BACH2	CUL1	ENSPPYP00000018860	ENSPPYP00000020352	BACH2 isoform 1.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.495
BACH2	FBXL17	ENSPPYP00000018860	ENSPPYP00000017523	BACH2 isoform 1.	FBXL17 isoform 1.	0.689
BACH2	MAFK	ENSPPYP00000018860	ENSPPYP00000019390	BACH2 isoform 1.	MAF bZIP transcription factor K.	0.933
BACH2	RBX1	ENSPPYP00000018860	ENSPPYP00000013235	BACH2 isoform 1.	RBX1 isoform 1.	0.497
BACH2	UBC	ENSPPYP00000018860	ENSPPYP00000005811	BACH2 isoform 1.	UBC isoform 2.	0.439
CR201_G0003353	CR201_G0053435	ENSPPYP00000007706	ENSPPYP00000002230	RPS27A isoform 1.	UBB isoform 1.	0.858
CR201_G0003353	CUL1	ENSPPYP00000007706	ENSPPYP00000020352	RPS27A isoform 1.	Cullin-1; Core component of multiple cullin-RING-based SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the [...]	0.692
CR201_G0003353	ENSPPYP00000022319	ENSPPYP00000007706	ENSPPYP00000022319	RPS27A isoform 1.	annotation not available	0.596
CR201_G0003353	FBXL17	ENSPPYP00000007706	ENSPPYP00000017523	RPS27A isoform 1.	FBXL17 isoform 1.	0.470
CR201_G0003353	RBX1	ENSPPYP00000007706	ENSPPYP00000013235	RPS27A isoform 1.	RBX1 isoform 1.	0.712
CR201_G0003353	SKP1	ENSPPYP00000007706	ENSPPYP00000017649	RPS27A isoform 1.	S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC [...]	0.596
CR201_G0003353	SKP2	ENSPPYP00000007706	ENSPPYP00000017203	RPS27A isoform 1.	SKP2 isoform 1.	0.666
CR201_G0003353	UBC	ENSPPYP00000007706	ENSPPYP00000005811	RPS27A isoform 1.	UBC isoform 2.	0.981