STRINGSTRING
PAX2 PAX2 AMOT AMOT OTC OTC CRB2 CRB2 ALDOB ALDOB OCLN OCLN FAT1 FAT1 ACOX2 ACOX2 GAPDHS GAPDHS HNF1B HNF1B ALDH2 ALDH2 GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAX2PAX2 isoform 3. (388 aa)
AMOTAMOT isoform 3. (1088 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
CRB2CRB2 isoform 2. (637 aa)
ALDOBFructose-bisphosphate aldolase B. (364 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. (522 aa)
FAT1FAT1 isoform 1. (4591 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (408 aa)
HNF1BHepatocyte nuclear factor 1-beta; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. (557 aa)
ALDH2Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. Belongs to the aldehyde dehydrogenase family. (517 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (335 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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