STRINGSTRING
PTK2 PTK2 PTK2B PTK2B FRMD1 FRMD1 JAK1 JAK1 PTPN14 PTPN14 PTPN13 PTPN13 FARP2 FARP2 PTPN4 PTPN4 EPB41L5 EPB41L5 MYO7B MYO7B PLEKHH2 PLEKHH2 NF2 NF2 EPB41L1 EPB41L1 FRMD7 FRMD7 FRMPD3 FRMPD3 FRMD5 FRMD5 EZR EZR EPB41L2 EPB41L2 MYLIP MYLIP EPB41L4A EPB41L4A CR201_G0015864 CR201_G0015864 CR201_G0018317 CR201_G0018317 CR201_G0048741 CR201_G0048741 CR201_G0023224 CR201_G0023224 RDX RDX FARP1 FARP1 FRMD6 FRMD6 FERMT2 FERMT2 PLEKHH1 PLEKHH1 PTPN21 PTPN21 TLN2 TLN2 MYO15A MYO15A PLEKHH3 PLEKHH3 EPB41L3 EPB41L3 JAK3 JAK3 FERMT1 FERMT1 MYO10 MYO10 MSN MSN FRMPD4 FRMPD4 PTPN3 PTPN3 EPB41L4B EPB41L4B FRMD3 FRMD3 JAK2 JAK2 TLN1 TLN1 FRMPD1 FRMPD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTK2PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa)
PTK2BPTK2B isoform 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FRMD1FRMD1 isoform 1. (548 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
PTPN13PTPN13 isoform 2. (2426 aa)
FARP2FARP2 isoform 1. (1048 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (925 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
MYO7BMYO7B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa)
NF2Neurofibromin 2. (590 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (881 aa)
FRMD7FERM domain containing 7. (714 aa)
FRMPD3FRMPD3 isoform 2. (1534 aa)
FRMD5FRMD5 isoform 8. (419 aa)
EZREZR isoform 1. (586 aa)
EPB41L2EPB41L2 isoform 10. (917 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
EPB41L4AEPB41L4A isoform 1. (651 aa)
CR201_G0015864EPB41 isoform 1. (655 aa)
CR201_G0018317FRMD4A isoform 1. (832 aa)
CR201_G0048741FRMPD2 isoform 5. (896 aa)
CR201_G0023224MYO7A isoform 2. (1350 aa)
RDXRDX isoform 3. (604 aa)
FARP1FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). (1045 aa)
FRMD6FERM domain containing 6. (614 aa)
FERMT2FERMT2 isoform 1. (623 aa)
PLEKHH1PLEKHH1 isoform 1. (1314 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1153 aa)
TLN2TLN2 isoform 1. (2542 aa)
MYO15AMYO15A isoform 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3281 aa)
PLEKHH3PLEKHH3 isoform 3. (756 aa)
EPB41L3EPB41L3 isoform 2. (792 aa)
JAK3Tyrosine-protein kinase. (1013 aa)
FERMT1Fermitin family homolog 1; Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity); Belongs to the kindlin family. (677 aa)
MYO10MYO10 isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2027 aa)
MSNMSN isoform 6. (577 aa)
FRMPD4FRMPD4 isoform 1. (1322 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (1024 aa)
EPB41L4BEPB41L4B isoform 2. (821 aa)
FRMD3FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. (556 aa)
JAK2Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1132 aa)
TLN1TLN1 isoform 1. (2541 aa)
FRMPD1FRMPD1 isoform 1. (1575 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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