STRINGSTRING
PTPN14 PTPN14 FARP1 FARP1 RDX RDX CR201_G0048741 CR201_G0048741 CR201_G0018317 CR201_G0018317 FRMD5 FRMD5 FRMD7 FRMD7 MSN MSN PTPN3 PTPN3 EPB41L4B EPB41L4B FRMD3 FRMD3 FRMD1 FRMD1 EZR EZR CR201_G0015864 CR201_G0015864 EPB41L2 EPB41L2 MYLIP MYLIP EPB41L4A EPB41L4A PTPN13 PTPN13 FRMD4B FRMD4B FARP2 FARP2 PTPN4 PTPN4 EPB41L5 EPB41L5 NF2 NF2 EPB41L1 EPB41L1 EPB41L3 EPB41L3 PTPN21 PTPN21 FRMD6 FRMD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
FARP1FERM, ARHGEF and pleckstrin domain-containing protein 1; Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity). (1045 aa)
RDXRDX isoform 3. (604 aa)
CR201_G0048741FRMPD2 isoform 5. (896 aa)
CR201_G0018317FRMD4A isoform 1. (832 aa)
FRMD5FRMD5 isoform 8. (419 aa)
FRMD7FERM domain containing 7. (714 aa)
MSNMSN isoform 6. (577 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (1024 aa)
EPB41L4BEPB41L4B isoform 2. (821 aa)
FRMD3FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. (556 aa)
FRMD1FRMD1 isoform 1. (548 aa)
EZREZR isoform 1. (586 aa)
CR201_G0015864EPB41 isoform 1. (655 aa)
EPB41L2EPB41L2 isoform 10. (917 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
EPB41L4AEPB41L4A isoform 1. (651 aa)
PTPN13PTPN13 isoform 2. (2426 aa)
FRMD4BFRMD4B isoform 1. (932 aa)
FARP2FARP2 isoform 1. (1048 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (925 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
NF2Neurofibromin 2. (590 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (881 aa)
EPB41L3EPB41L3 isoform 2. (792 aa)
PTPN21Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1153 aa)
FRMD6FERM domain containing 6. (614 aa)
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.