(5 nodes) Glutathione S-transferase, C-terminal domain, and SAM complex network (Homo sapiens)

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protein homology

Your Input:
	MTX2	Metaxin-2; Involved in transport of proteins into the mitochondrion. (263 aa)
	SAMM50	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex. (469 aa)
	MTX1	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). (466 aa)
	DNAJC11	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. (559 aa)
	MTX3	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family. (312 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNAJC11	MTX1	ENSP00000366800	ENSP00000357360	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	0.949
DNAJC11	MTX2	ENSP00000366800	ENSP00000249442	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	Metaxin-2; Involved in transport of proteins into the mitochondrion.	0.936
DNAJC11	MTX3	ENSP00000366800	ENSP00000424798	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	0.859
DNAJC11	SAMM50	ENSP00000366800	ENSP00000345445	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	0.975
MTX1	DNAJC11	ENSP00000357360	ENSP00000366800	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	0.949
MTX1	MTX2	ENSP00000357360	ENSP00000249442	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	Metaxin-2; Involved in transport of proteins into the mitochondrion.	0.996
MTX1	MTX3	ENSP00000357360	ENSP00000424798	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	0.847
MTX1	SAMM50	ENSP00000357360	ENSP00000345445	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	0.998
MTX2	DNAJC11	ENSP00000249442	ENSP00000366800	Metaxin-2; Involved in transport of proteins into the mitochondrion.	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	0.936
MTX2	MTX1	ENSP00000249442	ENSP00000357360	Metaxin-2; Involved in transport of proteins into the mitochondrion.	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	0.996
MTX2	MTX3	ENSP00000249442	ENSP00000424798	Metaxin-2; Involved in transport of proteins into the mitochondrion.	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	0.984
MTX2	SAMM50	ENSP00000249442	ENSP00000345445	Metaxin-2; Involved in transport of proteins into the mitochondrion.	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	0.999
MTX3	DNAJC11	ENSP00000424798	ENSP00000366800	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	0.859
MTX3	MTX1	ENSP00000424798	ENSP00000357360	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	0.847
MTX3	MTX2	ENSP00000424798	ENSP00000249442	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	Metaxin-2; Involved in transport of proteins into the mitochondrion.	0.984
MTX3	SAMM50	ENSP00000424798	ENSP00000345445	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	0.993
SAMM50	DNAJC11	ENSP00000345445	ENSP00000366800	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family.	0.975
SAMM50	MTX1	ENSP00000345445	ENSP00000357360	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity).	0.998
SAMM50	MTX2	ENSP00000345445	ENSP00000249442	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	Metaxin-2; Involved in transport of proteins into the mitochondrion.	0.999
SAMM50	MTX3	ENSP00000345445	ENSP00000424798	Sorting and assembly machinery component 50 homolog; Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.	Metaxin-3; Could function in transport of proteins into the mitochondrion; Belongs to the metaxin family.	0.993