STRINGSTRING
ABCA6 ABCA6 ABCF2-2 ABCF2-2 ABCC12 ABCC12 ABCC5 ABCC5 ABCA9 ABCA9 ABCC10 ABCC10 SVEP1 SVEP1 ABCA5 ABCA5 ABCC11 ABCC11 ABCB5 ABCB5 ABCA8 ABCA8 ABCG4 ABCG4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCA6ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family. (1617 aa)
ABCF2-2ATP binding cassette subfamily F member 2. (623 aa)
ABCC12Multidrug resistance-associated protein 9; Probable transporter. (1359 aa)
ABCC5Multidrug resistance-associated protein 5; Acts as a multispecific organic anion pump which can transport nucleotide analogs; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. (1437 aa)
ABCA9ATP-binding cassette sub-family A member 9; May play a role in monocyte differentiation and lipid homeostasis; Belongs to the ABC transporter superfamily. ABCA family. (1624 aa)
ABCC10Multidrug resistance-associated protein 7; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. (1492 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process. (3571 aa)
ABCA5ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes. Belongs to the ABC transporter superfamily. ABCA family. (1642 aa)
ABCC11ATP-binding cassette sub-family C member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S- glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta- D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taur [...] (1382 aa)
ABCB5ATP-binding cassette sub-family B member 5; Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. (1257 aa)
ABCA8ATP-binding cassette sub-family A member 8; ATP-dependent lipophilic drug transporter. (1621 aa)
ABCG4ATP-binding cassette sub-family G member 4; May be involved in macrophage lipid homeostasis. (646 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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