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GOLGA5 GOLGA5 COG3 COG3 COG5 COG5 COG1 COG1 COG7 COG7 COG4 COG4 CUX1 CUX1 COG2 COG2 COG6 COG6 GOLIM4 GOLIM4 H3BMQ9_HUMAN H3BMQ9_HUMAN H3BUN2_HUMAN H3BUN2_HUMAN COG8 COG8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GOLGA5Golgin subfamily A member 5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport. (731 aa)
COG3Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport. (828 aa)
COG5Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family. (860 aa)
COG1Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function. (980 aa)
COG7Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. (770 aa)
COG4Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. Belongs to the COG4 family. (789 aa)
CUX1Homeobox protein cut-like 1; Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III. Also involved in the control of synaptogenesis. In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heav [...] (1516 aa)
COG2Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family. (738 aa)
COG6Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family. (657 aa)
GOLIM4Golgi integral membrane protein 4; Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi. (696 aa)
H3BMQ9_HUMANUncharacterized protein. (156 aa)
H3BUN2_HUMANUncharacterized protein. (164 aa)
COG8Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function. (612 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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