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| | EEF1A2 | Elongation factor 1-alpha 2; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (463 aa) |
| | EDF1 | Endothelial differentiation-related factor 1; Transcriptional coactivator stimulating NR5A1 and ligand- dependent NR1H3/LXRA and PPARG transcriptional activities. Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1. Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm. May function in endothelial cells differentiation, hormone- induced cardiomyocytes hypertrophy and lipid metabolism. (148 aa) |
| | RPL19 | Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (196 aa) |
| | RPS12 | Ribosomal protein S12. (132 aa) |
| | RPS4Y1 | Ribosomal protein S4 Y-linked 1; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa) |
| | RSAD1 | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity (Probable). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine (By similarity); Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily. (442 aa) |
| | RPL35 | 60S ribosomal protein L35; Component of the large ribosomal subunit. (123 aa) |
| | RPL8 | 60S ribosomal protein L8; Component of the large ribosomal subunit. (257 aa) |
| | RPL3L | Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (407 aa) |
| | RPS11 | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa) |
| | RPS27A | Ubiquitin-40S ribosomal protein S27a; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be i [...] (156 aa) |
| | RPL37 | 60S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (97 aa) |
| | RPS3 | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] (259 aa) |
| | CCDC105 | Coiled-coil domain containing 105. (499 aa) |
| | MRNIP | MRN complex-interacting protein; Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair. (343 aa) |
| | RPL29 | 60S ribosomal protein L29; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL29 family. (159 aa) |
| | RPS23 | 40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (143 aa) |
| | RPL10L | 60S ribosomal protein L10-like; May play a role in compensating for the inactivated X-linked gene during spermatogenesis. (214 aa) |
| | ARL6IP1 | ADP-ribosylation factor-like protein 6-interacting protein 1; Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity- dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport (By similarity). Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-depend [...] (203 aa) |
| | RPL13 | Ribosomal protein L13. (211 aa) |
| | RPL15 | Ribosomal protein L15. (204 aa) |
| | RPL38 | Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa) |
| | RPL4 | Ribosomal protein L4. (427 aa) |
| | RPS15A | 40S ribosomal protein S15a; Structural component of the ribosome. Required for proper erythropoiesis. (130 aa) |
| | TUFM | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (455 aa) |
| | RPS27L | Ribosomal protein S27 like; Belongs to the eukaryotic ribosomal protein eS27 family. (84 aa) |
| | EEF1G | Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. (437 aa) |
| | MRPL12 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. (198 aa) |
| | EEF1A1 | Elongation factor 1-alpha 1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa) |
| | RPL7 | 60S ribosomal protein L7; Component of the large ribosomal subunit. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs. (248 aa) |
| | MRPL20 | Mitochondrial ribosomal protein L20. (149 aa) |
| | RPS2 | Ribosomal protein S2. (293 aa) |
| | RPS21 | Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa) |
| | RPL3 | 60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes. (403 aa) |
| | RPL36AL | Ribosomal protein L36a like; Belongs to the eukaryotic ribosomal protein eL42 family. (106 aa) |
| | RPL27A | Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | RPL21 | 60S ribosomal protein L21; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL21 family. (160 aa) |
| | RPLP1 | 60S acidic ribosomal protein P1; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | RPS3A | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3; Belongs to the eukaryotic ribosomal protein eS1 family. (264 aa) |
| | RPL22L1 | Ribosomal protein L22 like 1; Belongs to the eukaryotic ribosomal protein eL22 family. (122 aa) |
| | RPL22 | Ribosomal protein L22; Belongs to the eukaryotic ribosomal protein eL22 family. (128 aa) |
| | PPP1R26 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. (1209 aa) |
| | RPL12 | 60S ribosomal protein L12; Binds directly to 26S ribosomal RNA. (165 aa) |
| | RPL39 | Ribosomal protein L39; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | AKNAD1 | Protein AKNAD1; AKNA domain containing 1. (836 aa) |
| | RPL5 | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (297 aa) |
| | CXorf66 | Uncharacterized protein CXorf66; Chromosome X open reading frame 66. (361 aa) |
| | SERBP1 | Plasminogen activator inhibitor 1 RNA-binding protein; May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. (408 aa) |
| | RPL7A | Ribosomal protein L7a. (266 aa) |
| | RPS4X | Ribosomal protein S4 X-linked; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa) |
| | RPL10A | 60S ribosomal protein L10a; Component of the large ribosomal subunit. (217 aa) |
| | WDR31 | WD repeat domain 31. (367 aa) |
| | HMGN4 | High mobility group nucleosomal binding domain 4; Belongs to the HMGN family. (90 aa) |
| | RPS16 | Ribosomal protein S16. (152 aa) |
| | RPS9 | Ribosomal protein S9. (194 aa) |
| | RPL13A | 60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppre [...] (203 aa) |
| | EEF1B2 | Elongation factor 1-beta; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. (225 aa) |
| | RPL24 | Ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family. (157 aa) |
| | RPL34 | 60S ribosomal protein L34; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL34 family. (117 aa) |
| | RPS29 | Ribosomal protein S29. (67 aa) |
| | RPL14 | 60S ribosomal protein L14; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL14 family. (215 aa) |
| | RPS8 | Ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa) |
| | RPS14 | Ribosomal protein S14. (151 aa) |
| | RPL36A-HNRNPH2 | RPL36A-HNRNPH2 readthrough; Belongs to the eukaryotic ribosomal protein eL42 family. (118 aa) |
| | RPL31 | Ribosomal protein L31. (128 aa) |
| | RPSA | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. (Microbial infection) Acts as a receptor for the Dengue virus [...] (300 aa) |
| | RPL39L | Ribosomal protein L39 like; Belongs to the eukaryotic ribosomal protein eL39 family. (51 aa) |
| | RPS18 | 40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA. (152 aa) |
| | IFI35 | Interferon-induced 35 kDa protein; Not yet known; Belongs to the NMI family. (288 aa) |
| | RPL6 | 60S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family. (288 aa) |
| | RPL36A | Ribosomal protein L36a. (142 aa) |
| | EEF1D | Elongation factor 1-delta; [Isoform 1]: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome; Belongs to the EF-1-beta/EF-1-delta family. (647 aa) |
| | DOCK4 | Dedicator of cytokinesis protein 4; Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP. (1975 aa) |
| | RPL10 | 60S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development. (214 aa) |
| | RPS24 | 40S ribosomal protein S24; Required for processing of pre-rRNA and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS24 family. (289 aa) |
| | RPL32 | Ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. (135 aa) |
| | RPL37A | Ribosomal protein L37a. (92 aa) |
| | RPL7L1 | Ribosomal protein L7 like 1. (255 aa) |
| | RPL23 | Ribosomal protein L23. (140 aa) |
| | MRPL36 | Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (103 aa) |
| | RACK1 | Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits. Binds to and stabilizes activated protein [...] (317 aa) |
| | RPL30 | Ribosomal protein L30. (115 aa) |
| | RPL26L1 | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. (145 aa) |
| | RPS20 | Ribosomal protein S20. (142 aa) |
| | EIF5AL1 | Eukaryotic translation initiation factor 5A-1-like; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation [...] (154 aa) |
| | RPLP2 | 60S acidic ribosomal protein P2; Plays an important role in the elongation step of protein synthesis. (115 aa) |
| | FAU | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. (133 aa) |
| | RPS25 | Ribosomal protein S25. (125 aa) |
| | RPS13 | Ribosomal protein S13. (151 aa) |
| | RPL18 | 60S ribosomal protein L18; Component of the large ribosomal subunit. (188 aa) |
| | RPLP0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa) |
| | RPL28 | 60S ribosomal protein L28; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL28 family. (170 aa) |
| | SMKR1 | Small lysine rich protein 1. (65 aa) |
| | H3BN98_HUMAN | Uncharacterized protein. (237 aa) |
| | H3BNC9_HUMAN | Uncharacterized protein. (584 aa) |
| | RPL17-C18orf32 | RPL17-C18orf32 readthrough; Belongs to the universal ribosomal protein uL22 family. (228 aa) |
| | RPL26 | 60S ribosomal protein L26; Component of the large ribosomal subunit. (145 aa) |
| | RPL17 | 60S ribosomal protein L17; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL22 family. (184 aa) |
| | RPL36 | 60S ribosomal protein L36; Component of the large ribosomal subunit. (105 aa) |
| | RPL27 | 60S ribosomal protein L27; Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs. (136 aa) |
| | RPS15 | Ribosomal protein S15. (152 aa) |
| | RPS19 | 40S ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits; Belongs to the eukaryotic ribosomal protein eS19 family. (145 aa) |
| | RPS28 | Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa) |
| | RPS5 | 40S ribosomal protein S5, N-terminally processed; Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa) |
| | TPT1 | Translationally-controlled tumor protein; Involved in calcium binding and microtubule stabilization. (197 aa) |
| | RPS10 | 40S ribosomal protein S10; Component of the 40S ribosomal subunit; Belongs to the eukaryotic ribosomal protein eS10 family. (165 aa) |
| | RSRC1 | Serine/Arginine-related protein 53; Has a role in alternative splicing and transcription regulation. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. (334 aa) |
| | RPS4Y2 | Ribosomal protein S4 Y-linked 2; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa) |
| | TEX48 | Testis-expressed protein 48; Testis expressed 48. (120 aa) |
| | RPS10-NUDT3 | RPS10-NUDT3 readthrough. (291 aa) |
| | RPL9 | Ribosomal protein L9. (192 aa) |
| | RPS7 | 40S ribosomal protein S7; Required for rRNA maturation. (194 aa) |
| | RPL35A | 60S ribosomal protein L35a; Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site. (110 aa) |
| | RPL11 | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (178 aa) |
| | RPS17 | Ribosomal protein S17. (135 aa) |
| | RPS27 | 40S ribosomal protein S27; Component of the small ribosomal subunit. Required for proper rRNA processing and maturation of 18S rRNAs ; Belongs to the eukaryotic ribosomal protein eS27 family. (84 aa) |
