Your Input: | |||||
| MMP16 | Matrix metalloproteinase-16; Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. Belongs to the peptidase M10A family. (607 aa) | ||||
| SPOCK2 | Testican-2; May participate in diverse steps of neurogenesis. Binds calcium. (424 aa) | ||||
| SPOCK3 | Testican-3; May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. (436 aa) | ||||
| SPOCK1 | Testican-1; May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system. (439 aa) | ||||
| ENSP00000499503 | Novel protein. (441 aa) | ||||