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| SECTM1 | Secreted and transmembrane protein 1; May be involved in thymocyte signaling. (248 aa) | ||||
| CD7 | T-cell antigen CD7; Not yet known. (240 aa) | ||||
| APCDD1 | Protein APCDD1; Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta- catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis; Belongs to the APCDD1 family. (514 aa) | ||||
| TPBG | Trophoblast glycoprotein; May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. (420 aa) | ||||
| TRABD2A | Metalloprotease TIKI1; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. (505 aa) | ||||