STRINGSTRING
REM1 REM1 ARRDC2 ARRDC2 RASL11A RASL11A RASL11B RASL11B REM2 REM2 ARL5A ARL5A RHEBL1 RHEBL1 ARL10 ARL10 SYDE2 SYDE2 NET1 NET1 CNKSR1 CNKSR1 ARL16 ARL16 ARL13A ARL13A E9PMD0_HUMAN E9PMD0_HUMAN H0YJX3_HUMAN H0YJX3_HUMAN ENSP00000461865 ENSP00000461865 U3KQV3_HUMAN U3KQV3_HUMAN ENSP00000490163 ENSP00000490163 ARL9 ARL9 CFAP298-TCP10L CFAP298-TCP10L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REM1GTP-binding protein REM 1; Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling. (298 aa)
ARRDC2Arrestin domain containing 2; Belongs to the arrestin family. (407 aa)
RASL11ARas-like protein family member 11A; Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription (By similarity); Belongs to the small GTPase superfamily. Ras family. (242 aa)
RASL11BRas-like protein family member 11B; RAS like family 11 member B. (248 aa)
REM2GTP-binding protein REM 2; Binds GTP saturably and exhibits a low intrinsic rate of GTP hydrolysis. (340 aa)
ARL5AADP-ribosylation factor-like protein 5A; Lacks ADP-ribosylation enhancing activity; Belongs to the small GTPase superfamily. Arf family. (179 aa)
RHEBL1GTPase RhebL1; Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2. (183 aa)
ARL10ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family. (244 aa)
SYDE2Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. (1194 aa)
NET1Neuroepithelial cell-transforming gene 1 protein; Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. (596 aa)
CNKSR1Connector enhancer of kinase suppressor of ras 1; May function as an adapter protein or regulator of Ras signaling pathways; Belongs to the CNKSR family. (720 aa)
ARL16ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. (197 aa)
ARL13AADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. (256 aa)
E9PMD0_HUMANUncharacterized protein. (336 aa)
H0YJX3_HUMANUncharacterized protein. (145 aa)
ENSP00000461865Novel protein. (44 aa)
U3KQV3_HUMANPPM-type phosphatase domain-containing protein. (271 aa)
ENSP00000490163Protein kinase domain-containing protein. (405 aa)
ARL9ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9. (265 aa)
CFAP298-TCP10LUncharacterized protein. (389 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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