11 items (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CFAP161	Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. (301 aa)
	ENKUR	Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel. (256 aa)
	CFAP52	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. (620 aa)
	TEKT1	Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family. (418 aa)
	CFAP126	Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. (177 aa)
	CFAP45	Cilia and flagella associated protein 45. (551 aa)
	C1orf194	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis. (157 aa)
	CFAP53	Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis. (514 aa)
	C5orf49	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49. (147 aa)
	C9orf116	UPF0691 protein C9orf116; Chromosome 9 open reading frame 116. (136 aa)
	EFHC2	EF-hand domain-containing family member C2; EF-hand domain containing 2. (749 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf194	C5orf49	ENSP00000358965	ENSP00000382708	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	0.875
C1orf194	C9orf116	ENSP00000358965	ENSP00000395281	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	UPF0691 protein C9orf116; Chromosome 9 open reading frame 116.	0.849
C1orf194	CFAP126	ENSP00000358965	ENSP00000356951	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.	0.931
C1orf194	CFAP161	ENSP00000358965	ENSP00000286732	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.	0.836
C1orf194	CFAP45	ENSP00000358965	ENSP00000357079	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Cilia and flagella associated protein 45.	0.860
C1orf194	CFAP52	ENSP00000358965	ENSP00000339449	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.871
C1orf194	CFAP53	ENSP00000358965	ENSP00000381553	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis.	0.850
C1orf194	EFHC2	ENSP00000358965	ENSP00000404232	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.844
C1orf194	ENKUR	ENSP00000358965	ENSP00000331044	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.	0.857
C1orf194	TEKT1	ENSP00000358965	ENSP00000341346	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family.	0.886
C5orf49	C1orf194	ENSP00000382708	ENSP00000358965	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.	0.875
C5orf49	C9orf116	ENSP00000382708	ENSP00000395281	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	UPF0691 protein C9orf116; Chromosome 9 open reading frame 116.	0.947
C5orf49	CFAP126	ENSP00000382708	ENSP00000356951	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Protein Flattop; Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.	0.861
C5orf49	CFAP161	ENSP00000382708	ENSP00000286732	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.	0.851
C5orf49	CFAP45	ENSP00000382708	ENSP00000357079	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Cilia and flagella associated protein 45.	0.829
C5orf49	CFAP52	ENSP00000382708	ENSP00000339449	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.873
C5orf49	CFAP53	ENSP00000382708	ENSP00000381553	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Cilia- and flagella-associated protein 53; May play a role in the beating of primary cilia and thereby be involved in the establishment of organ laterality during embryogenesis.	0.873
C5orf49	EFHC2	ENSP00000382708	ENSP00000404232	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.809
C5orf49	ENKUR	ENSP00000382708	ENSP00000331044	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel.	0.878
C5orf49	TEKT1	ENSP00000382708	ENSP00000341346	Uncharacterized protein C5orf49; Chromosome 5 open reading frame 49.	Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family.	0.846