(7 nodes) Mixed, incl. Domain of unknown function DUF4537, and CCDC92/74, N-terminal network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCDC92	Coiled-coil domain containing 92. (331 aa)
	FBXO36	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. (188 aa)
	ANKEF1	Ankyrin repeat and EF-hand domain containing 1. (776 aa)
	VWA3B	Von Willebrand factor A domain containing 3B. (1294 aa)
	ZNF664	Zinc finger protein 664; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (261 aa)
	CFAP99	Cilia and flagella associated protein 99. (646 aa)
	DNAH10	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain. (4471 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKEF1	CFAP99	ENSP00000367644	ENSP00000480601	Ankyrin repeat and EF-hand domain containing 1.	Cilia and flagella associated protein 99.	0.618
ANKEF1	DNAH10	ENSP00000367644	ENSP00000489675	Ankyrin repeat and EF-hand domain containing 1.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.606
ANKEF1	FBXO36	ENSP00000367644	ENSP00000283946	Ankyrin repeat and EF-hand domain containing 1.	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	0.602
CCDC92	DNAH10	ENSP00000238156	ENSP00000489675	Coiled-coil domain containing 92.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.794
CCDC92	ZNF664	ENSP00000238156	ENSP00000441405	Coiled-coil domain containing 92.	Zinc finger protein 664; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.798
CFAP99	ANKEF1	ENSP00000480601	ENSP00000367644	Cilia and flagella associated protein 99.	Ankyrin repeat and EF-hand domain containing 1.	0.618
CFAP99	DNAH10	ENSP00000480601	ENSP00000489675	Cilia and flagella associated protein 99.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.616
CFAP99	VWA3B	ENSP00000480601	ENSP00000417955	Cilia and flagella associated protein 99.	Von Willebrand factor A domain containing 3B.	0.597
DNAH10	ANKEF1	ENSP00000489675	ENSP00000367644	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	Ankyrin repeat and EF-hand domain containing 1.	0.606
DNAH10	CCDC92	ENSP00000489675	ENSP00000238156	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	Coiled-coil domain containing 92.	0.794
DNAH10	CFAP99	ENSP00000489675	ENSP00000480601	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	Cilia and flagella associated protein 99.	0.616
DNAH10	FBXO36	ENSP00000489675	ENSP00000283946	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	0.611
DNAH10	VWA3B	ENSP00000489675	ENSP00000417955	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	Von Willebrand factor A domain containing 3B.	0.637
DNAH10	ZNF664	ENSP00000489675	ENSP00000441405	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	Zinc finger protein 664; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.702
FBXO36	ANKEF1	ENSP00000283946	ENSP00000367644	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	Ankyrin repeat and EF-hand domain containing 1.	0.602
FBXO36	DNAH10	ENSP00000283946	ENSP00000489675	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.611
FBXO36	VWA3B	ENSP00000283946	ENSP00000417955	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	Von Willebrand factor A domain containing 3B.	0.603
VWA3B	CFAP99	ENSP00000417955	ENSP00000480601	Von Willebrand factor A domain containing 3B.	Cilia and flagella associated protein 99.	0.597
VWA3B	DNAH10	ENSP00000417955	ENSP00000489675	Von Willebrand factor A domain containing 3B.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.637
VWA3B	FBXO36	ENSP00000417955	ENSP00000283946	Von Willebrand factor A domain containing 3B.	F-box only protein 36; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.	0.603