(7 nodes) Mixed, incl. T-complex protein 10 family, and Lactate biosynthetic process network (Homo sapiens)

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	RSPH3	Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family. (560 aa)
	C12orf4	Protein C12orf4; Plays a role in mast cell degranulation. (552 aa)
	PPP1R21	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. (780 aa)
	TCP10L	T-complex protein 10A homolog 1; May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells. (215 aa)
	GATD1	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family. (220 aa)
	CRYZL1	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (349 aa)
	TBCK	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization. (893 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf4	CRYZL1	ENSP00000261250	ENSP00000370966	Protein C12orf4; Plays a role in mast cell degranulation.	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	0.627
C12orf4	GATD1	ENSP00000261250	ENSP00000321691	Protein C12orf4; Plays a role in mast cell degranulation.	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	0.402
C12orf4	PPP1R21	ENSP00000261250	ENSP00000294952	Protein C12orf4; Plays a role in mast cell degranulation.	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	0.818
C12orf4	TBCK	ENSP00000261250	ENSP00000378198	Protein C12orf4; Plays a role in mast cell degranulation.	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization.	0.892
C12orf4	TCP10L	ENSP00000261250	ENSP00000300258	Protein C12orf4; Plays a role in mast cell degranulation.	T-complex protein 10A homolog 1; May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells.	0.625
CRYZL1	C12orf4	ENSP00000370966	ENSP00000261250	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	Protein C12orf4; Plays a role in mast cell degranulation.	0.627
CRYZL1	GATD1	ENSP00000370966	ENSP00000321691	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	0.819
CRYZL1	PPP1R21	ENSP00000370966	ENSP00000294952	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	0.942
GATD1	C12orf4	ENSP00000321691	ENSP00000261250	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	Protein C12orf4; Plays a role in mast cell degranulation.	0.402
GATD1	CRYZL1	ENSP00000321691	ENSP00000370966	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	0.819
GATD1	PPP1R21	ENSP00000321691	ENSP00000294952	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	0.918
PPP1R21	C12orf4	ENSP00000294952	ENSP00000261250	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	Protein C12orf4; Plays a role in mast cell degranulation.	0.818
PPP1R21	CRYZL1	ENSP00000294952	ENSP00000370966	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	Quinone oxidoreductase-like protein 1; Crystallin zeta like 1; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.	0.942
PPP1R21	GATD1	ENSP00000294952	ENSP00000321691	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	Glutamine amidotransferase like class 1 domain containing 1; Belongs to the peptidase C56 family.	0.918
PPP1R21	RSPH3	ENSP00000294952	ENSP00000252655	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family.	0.955
PPP1R21	TBCK	ENSP00000294952	ENSP00000378198	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization.	0.608
RSPH3	PPP1R21	ENSP00000252655	ENSP00000294952	Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia. Belongs to the flagellar radial spoke RSP3 family.	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	0.955
TBCK	C12orf4	ENSP00000378198	ENSP00000261250	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization.	Protein C12orf4; Plays a role in mast cell degranulation.	0.892
TBCK	PPP1R21	ENSP00000378198	ENSP00000294952	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization.	Protein phosphatase 1 regulatory subunit 21; Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.	0.608
TBCK	TCP10L	ENSP00000378198	ENSP00000300258	TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization.	T-complex protein 10A homolog 1; May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells.	0.593