| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANKS1A | FAM180A | ENSP00000353518 | ENSP00000342336 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | Protein FAM180A; Family with sequence similarity 180 member A. | 0.514 |
| ANKS1A | KLHL35 | ENSP00000353518 | ENSP00000438526 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | Kelch-like protein 35; Kelch like family member 35. | 0.516 |
| ANKS1A | PI15 | ENSP00000353518 | ENSP00000260113 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. | 0.467 |
| ANKS1A | SCUBE3 | ENSP00000353518 | ENSP00000274938 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | Signal peptide, CUB and EGF-like domain-containing protein 3; Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression. | 0.580 |
| ANKS1A | SLC25A29 | ENSP00000353518 | ENSP00000352167 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | Mitochondrial basic amino acids transporter; Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms ; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.483 |
| ANKS1A | TCP11 | ENSP00000353518 | ENSP00000501201 | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.629 |
| BEGAIN | SLC25A29 | ENSP00000411124 | ENSP00000352167 | Brain-enriched guanylate kinase-associated protein; May sustain the structure of the postsynaptic density (PSD). | Mitochondrial basic amino acids transporter; Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms ; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.618 |
| ENSP00000418875 | THEGL | ENSP00000418875 | ENSP00000456850 | Probable threonine protease PRSS50. | Testicular haploid expressed gene protein-like; Theg spermatid protein like. | 0.400 |
| FAM180A | ANKS1A | ENSP00000342336 | ENSP00000353518 | Protein FAM180A; Family with sequence similarity 180 member A. | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | 0.514 |
| FAM180A | KLHL35 | ENSP00000342336 | ENSP00000438526 | Protein FAM180A; Family with sequence similarity 180 member A. | Kelch-like protein 35; Kelch like family member 35. | 0.485 |
| FAM180A | PI15 | ENSP00000342336 | ENSP00000260113 | Protein FAM180A; Family with sequence similarity 180 member A. | Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. | 0.566 |
| FAM180A | SLC25A29 | ENSP00000342336 | ENSP00000352167 | Protein FAM180A; Family with sequence similarity 180 member A. | Mitochondrial basic amino acids transporter; Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms ; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.517 |
| FAM180A | TCP11 | ENSP00000342336 | ENSP00000501201 | Protein FAM180A; Family with sequence similarity 180 member A. | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.473 |
| KLHL35 | ANKS1A | ENSP00000438526 | ENSP00000353518 | Kelch-like protein 35; Kelch like family member 35. | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | 0.516 |
| KLHL35 | FAM180A | ENSP00000438526 | ENSP00000342336 | Kelch-like protein 35; Kelch like family member 35. | Protein FAM180A; Family with sequence similarity 180 member A. | 0.485 |
| KLHL35 | PI15 | ENSP00000438526 | ENSP00000260113 | Kelch-like protein 35; Kelch like family member 35. | Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. | 0.500 |
| KLHL35 | SCUBE3 | ENSP00000438526 | ENSP00000274938 | Kelch-like protein 35; Kelch like family member 35. | Signal peptide, CUB and EGF-like domain-containing protein 3; Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression. | 0.478 |
| KLHL35 | TCP11 | ENSP00000438526 | ENSP00000501201 | Kelch-like protein 35; Kelch like family member 35. | T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. | 0.527 |
| PI15 | ANKS1A | ENSP00000260113 | ENSP00000353518 | Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. | Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). | 0.467 |
| PI15 | FAM180A | ENSP00000260113 | ENSP00000342336 | Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. | Protein FAM180A; Family with sequence similarity 180 member A. | 0.566 |