(6 nodes) Mixed, incl. FAM180 family, and Regulation of ephrin receptor signaling pathway network (Homo sapiens)

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Your Input:
	PI15	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family. (258 aa)
	FAM180A	Protein FAM180A; Family with sequence similarity 180 member A. (173 aa)
	ANKS1A	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity). (1134 aa)
	ZNF76	Zinc finger protein 76; May be involved in transcriptional regulation. (570 aa)
	KLHL35	Kelch-like protein 35; Kelch like family member 35. (583 aa)
	TCP11	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family. (516 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKS1A	FAM180A	ENSP00000353518	ENSP00000342336	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	Protein FAM180A; Family with sequence similarity 180 member A.	0.514
ANKS1A	KLHL35	ENSP00000353518	ENSP00000438526	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	Kelch-like protein 35; Kelch like family member 35.	0.516
ANKS1A	PI15	ENSP00000353518	ENSP00000260113	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	0.467
ANKS1A	TCP11	ENSP00000353518	ENSP00000501201	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	0.629
FAM180A	ANKS1A	ENSP00000342336	ENSP00000353518	Protein FAM180A; Family with sequence similarity 180 member A.	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	0.514
FAM180A	KLHL35	ENSP00000342336	ENSP00000438526	Protein FAM180A; Family with sequence similarity 180 member A.	Kelch-like protein 35; Kelch like family member 35.	0.485
FAM180A	PI15	ENSP00000342336	ENSP00000260113	Protein FAM180A; Family with sequence similarity 180 member A.	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	0.566
FAM180A	TCP11	ENSP00000342336	ENSP00000501201	Protein FAM180A; Family with sequence similarity 180 member A.	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	0.473
KLHL35	ANKS1A	ENSP00000438526	ENSP00000353518	Kelch-like protein 35; Kelch like family member 35.	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	0.516
KLHL35	FAM180A	ENSP00000438526	ENSP00000342336	Kelch-like protein 35; Kelch like family member 35.	Protein FAM180A; Family with sequence similarity 180 member A.	0.485
KLHL35	PI15	ENSP00000438526	ENSP00000260113	Kelch-like protein 35; Kelch like family member 35.	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	0.500
KLHL35	TCP11	ENSP00000438526	ENSP00000501201	Kelch-like protein 35; Kelch like family member 35.	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	0.527
PI15	ANKS1A	ENSP00000260113	ENSP00000353518	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	0.467
PI15	FAM180A	ENSP00000260113	ENSP00000342336	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	Protein FAM180A; Family with sequence similarity 180 member A.	0.566
PI15	KLHL35	ENSP00000260113	ENSP00000438526	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	Kelch-like protein 35; Kelch like family member 35.	0.500
PI15	TCP11	ENSP00000260113	ENSP00000501201	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	0.448
TCP11	ANKS1A	ENSP00000501201	ENSP00000353518	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	Ankyrin repeat and SAM domain-containing protein 1A; Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).	0.629
TCP11	FAM180A	ENSP00000501201	ENSP00000342336	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	Protein FAM180A; Family with sequence similarity 180 member A.	0.473
TCP11	KLHL35	ENSP00000501201	ENSP00000438526	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	Kelch-like protein 35; Kelch like family member 35.	0.527
TCP11	PI15	ENSP00000501201	ENSP00000260113	T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization- promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. Belongs to the TCP11 family.	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	0.448