(21 nodes) Leucine-rich repeat, typical subtype, and Regulation of heart looping network (Homo sapiens)

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Your Input:
	LRRC58	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58. (371 aa)
	LRG1	Leucine rich alpha-2-glycoprotein 1. (347 aa)
	LRRC28	Leucine-rich repeat-containing protein 28; Leucine rich repeat containing 28. (367 aa)
	LRRC14B	Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily. (514 aa)
	FSD2	Fibronectin type III and SPRY domain containing 2. (749 aa)
	LRRC20	Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20. (184 aa)
	ZNF770	Zinc finger protein 770; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (691 aa)
	LRRC10	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. (277 aa)
	LINGO4	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4. (593 aa)
	LRRC26	Leucine-rich repeat-containing protein 26; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium. (334 aa)
	BSPRY	B box and SPRY domain-containing protein; May regulate epithelial calcium transport by inhibiting TRPV5 activity. (402 aa)
	RNF207	RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner. (634 aa)
	LRRC10B	Leucine-rich repeat-containing protein 10B; Leucine rich repeat containing 10B. (292 aa)
	GPALPP1	GPALPP motifs containing 1. (340 aa)
	LRRC30	Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30. (301 aa)
	LRRC2	Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2. (371 aa)
	PODNL1	Podocan-like protein 1; Podocan like 1. (510 aa)
	ASB8	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. (288 aa)
	LRRC39	Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart. (339 aa)
	PLEKHG4B	Pleckstrin homology and RhoGEF domain containing G4B. (1627 aa)
	CCDC82	Coiled-coil domain containing 82. (544 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB8	LRRC14B	ENSP00000445622	ENSP00000327675	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Leucine-rich repeat-containing protein 14B; Leucine rich repeat containing 14B; Belongs to the PRAME family. LRRC14 subfamily.	0.428
ASB8	LRRC20	ENSP00000445622	ENSP00000348043	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20.	0.488
ASB8	LRRC28	ENSP00000445622	ENSP00000304923	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Leucine-rich repeat-containing protein 28; Leucine rich repeat containing 28.	0.481
ASB8	LRRC30	ENSP00000445622	ENSP00000372959	Ankyrin repeat and SOCS box protein 8; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30.	0.492
CCDC82	GPALPP1	ENSP00000495063	ENSP00000368447	Coiled-coil domain containing 82.	GPALPP motifs containing 1.	0.597
CCDC82	LRRC2	ENSP00000495063	ENSP00000379241	Coiled-coil domain containing 82.	Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2.	0.513
FSD2	LRRC39	ENSP00000335651	ENSP00000480740	Fibronectin type III and SPRY domain containing 2.	Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart.	0.626
FSD2	RNF207	ENSP00000335651	ENSP00000367173	Fibronectin type III and SPRY domain containing 2.	RING finger protein 207; Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.	0.503
GPALPP1	CCDC82	ENSP00000368447	ENSP00000495063	GPALPP motifs containing 1.	Coiled-coil domain containing 82.	0.597
GPALPP1	LRRC2	ENSP00000368447	ENSP00000379241	GPALPP motifs containing 1.	Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2.	0.546
LINGO4	LRRC10	ENSP00000357810	ENSP00000355166	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.493
LINGO4	LRRC10B	ENSP00000357810	ENSP00000367315	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	Leucine-rich repeat-containing protein 10B; Leucine rich repeat containing 10B.	0.431
LINGO4	LRRC2	ENSP00000357810	ENSP00000379241	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2.	0.437
LINGO4	LRRC30	ENSP00000357810	ENSP00000372959	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	Leucine-rich repeat-containing protein 30; Leucine rich repeat containing 30.	0.478
LINGO4	LRRC39	ENSP00000357810	ENSP00000480740	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart.	0.449
LRG1	LRRC10	ENSP00000302621	ENSP00000355166	Leucine rich alpha-2-glycoprotein 1.	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.536
LRG1	LRRC2	ENSP00000302621	ENSP00000379241	Leucine rich alpha-2-glycoprotein 1.	Leucine-rich repeat-containing protein 2; Leucine rich repeat containing 2.	0.530
LRG1	LRRC20	ENSP00000302621	ENSP00000348043	Leucine rich alpha-2-glycoprotein 1.	Leucine-rich repeat-containing protein 20; Leucine rich repeat containing 20.	0.434
LRRC10	LINGO4	ENSP00000355166	ENSP00000357810	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 4; Leucine rich repeat and Ig domain containing 4.	0.493
LRRC10	LRG1	ENSP00000355166	ENSP00000302621	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Leucine rich alpha-2-glycoprotein 1.	0.536