STRINGSTRING
TBC1D12 TBC1D12 PLEKHS1 PLEKHS1 TMEM50A TMEM50A CCDC107 CCDC107 LEPROTL1 LEPROTL1 TMEM50B TMEM50B LEPROT LEPROT
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBC1D12TBC1 domain family member 12; RAB11A-binding protein that plays a role in neurite outgrowth. (775 aa)
PLEKHS1Pleckstrin homology domain containing S1. (465 aa)
TMEM50ATransmembrane protein 50A; Belongs to the UPF0220 family. (157 aa)
CCDC107Coiled-coil domain containing 107. (283 aa)
LEPROTL1Leptin receptor overlapping transcript-like 1; Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. Belongs to the OB-RGRP/VPS55 family. (169 aa)
TMEM50BTransmembrane protein 50B; Belongs to the UPF0220 family. (158 aa)
LEPROTLeptin receptor gene-related protein; Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability. (140 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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