node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP20 | BRWD3 | ENSP00000260283 | ENSP00000362372 | Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | 0.958 |
ATAD2B | BRWD3 | ENSP00000238789 | ENSP00000362372 | ATPase family AAA domain containing 2B. | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | 0.562 |
ATAD2B | PHIP | ENSP00000238789 | ENSP00000275034 | ATPase family AAA domain containing 2B. | PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization. | 0.586 |
ATAD2B | SP140L | ENSP00000238789 | ENSP00000397911 | ATPase family AAA domain containing 2B. | SP140 nuclear body protein like. | 0.404 |
BRWD3 | ARHGAP20 | ENSP00000362372 | ENSP00000260283 | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.958 |
BRWD3 | ATAD2B | ENSP00000362372 | ENSP00000238789 | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | ATPase family AAA domain containing 2B. | 0.562 |
BRWD3 | PHIP | ENSP00000362372 | ENSP00000275034 | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization. | 0.552 |
BRWD3 | SP140L | ENSP00000362372 | ENSP00000397911 | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | SP140 nuclear body protein like. | 0.421 |
PHIP | ATAD2B | ENSP00000275034 | ENSP00000238789 | PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization. | ATPase family AAA domain containing 2B. | 0.586 |
PHIP | BRWD3 | ENSP00000275034 | ENSP00000362372 | PH-interacting protein; Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization. | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | 0.552 |
SP140 | SP140L | ENSP00000375899 | ENSP00000397911 | Nuclear body protein SP140; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails. | SP140 nuclear body protein like. | 0.903 |
SP140 | TENT5C | ENSP00000375899 | ENSP00000358458 | Nuclear body protein SP140; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails. | Terminal nucleotidyltransferase 5C; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death. | 0.592 |
SP140L | ATAD2B | ENSP00000397911 | ENSP00000238789 | SP140 nuclear body protein like. | ATPase family AAA domain containing 2B. | 0.404 |
SP140L | BRWD3 | ENSP00000397911 | ENSP00000362372 | SP140 nuclear body protein like. | Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. | 0.421 |
SP140L | SP140 | ENSP00000397911 | ENSP00000375899 | SP140 nuclear body protein like. | Nuclear body protein SP140; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails. | 0.903 |
TENT5C | SP140 | ENSP00000358458 | ENSP00000375899 | Terminal nucleotidyltransferase 5C; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death. | Nuclear body protein SP140; Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails. | 0.592 |