(8 nodes) Mixed, incl. SH3-binding, glutamic acid-rich protein, and Lebercilin-like network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BRWD1	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. (2320 aa)
	SH3BGR	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family. (239 aa)
	LCA5L	Lebercilin-like protein; Lebercilin LCA5 like. (670 aa)
	SH3BGRL	SH3 domain-binding glutamic acid-rich-like protein; SH3 domain binding glutamate rich protein like. (114 aa)
	CCDC171	Coiled-coil domain containing 171. (1326 aa)
	SLC35G5	Solute carrier family 35 member G5. (338 aa)
	XKR6	XK-related protein 6; XK related 6; Belongs to the XK family. (641 aa)
	TTC39B	Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3). (682 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRWD1	LCA5L	ENSP00000330753	ENSP00000351008	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	Lebercilin-like protein; Lebercilin LCA5 like.	0.472
BRWD1	SH3BGR	ENSP00000330753	ENSP00000332513	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	0.404
CCDC171	TTC39B	ENSP00000370077	ENSP00000422496	Coiled-coil domain containing 171.	Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).	0.529
LCA5L	BRWD1	ENSP00000351008	ENSP00000330753	Lebercilin-like protein; Lebercilin LCA5 like.	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	0.472
LCA5L	SH3BGR	ENSP00000351008	ENSP00000332513	Lebercilin-like protein; Lebercilin LCA5 like.	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	0.658
LCA5L	SH3BGRL	ENSP00000351008	ENSP00000362308	Lebercilin-like protein; Lebercilin LCA5 like.	SH3 domain-binding glutamic acid-rich-like protein; SH3 domain binding glutamate rich protein like.	0.568
LCA5L	XKR6	ENSP00000351008	ENSP00000416707	Lebercilin-like protein; Lebercilin LCA5 like.	XK-related protein 6; XK related 6; Belongs to the XK family.	0.539
SH3BGR	BRWD1	ENSP00000332513	ENSP00000330753	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	Bromodomain and WD repeat-containing protein 1; May be a transcriptional activator. May be involved in chromatin remodeling (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	0.404
SH3BGR	LCA5L	ENSP00000332513	ENSP00000351008	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	Lebercilin-like protein; Lebercilin LCA5 like.	0.658
SH3BGR	XKR6	ENSP00000332513	ENSP00000416707	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	XK-related protein 6; XK related 6; Belongs to the XK family.	0.431
SH3BGRL	LCA5L	ENSP00000362308	ENSP00000351008	SH3 domain-binding glutamic acid-rich-like protein; SH3 domain binding glutamate rich protein like.	Lebercilin-like protein; Lebercilin LCA5 like.	0.568
SLC35G5	TTC39B	ENSP00000371872	ENSP00000422496	Solute carrier family 35 member G5.	Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).	0.445
SLC35G5	XKR6	ENSP00000371872	ENSP00000416707	Solute carrier family 35 member G5.	XK-related protein 6; XK related 6; Belongs to the XK family.	0.580
TTC39B	CCDC171	ENSP00000422496	ENSP00000370077	Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).	Coiled-coil domain containing 171.	0.529
TTC39B	SLC35G5	ENSP00000422496	ENSP00000371872	Tetratricopeptide repeat protein 39B; Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3).	Solute carrier family 35 member G5.	0.445
XKR6	LCA5L	ENSP00000416707	ENSP00000351008	XK-related protein 6; XK related 6; Belongs to the XK family.	Lebercilin-like protein; Lebercilin LCA5 like.	0.539
XKR6	SH3BGR	ENSP00000416707	ENSP00000332513	XK-related protein 6; XK related 6; Belongs to the XK family.	SH3 domain-binding glutamic acid-rich protein; SH3 domain binding glutamate rich protein; Belongs to the SH3BGR family.	0.431
XKR6	SLC35G5	ENSP00000416707	ENSP00000371872	XK-related protein 6; XK related 6; Belongs to the XK family.	Solute carrier family 35 member G5.	0.580