STRINGSTRING
TGM6 TGM6 ENOX1 ENOX1 ASB17 ASB17 CCDC126 CCDC126 OR5J2 OR5J2 DPY19L3 DPY19L3 LVRN LVRN CCDC154 CCDC154 IQCN IQCN STMP1 STMP1 OR5M11 OR5M11 OR5M10 OR5M10 ADAM8 ADAM8 GALNTL5 GALNTL5 ZNF658 ZNF658 GOLGA6L7 GOLGA6L7 C2orf81 C2orf81 JAKMIP3 JAKMIP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGM6Protein-glutamine gamma-glutamyltransferase 6; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins; Belongs to the transglutaminase superfamily. Transglutaminase family. (706 aa)
ENOX1Protein disulfide-thiol oxidoreductase; Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. (643 aa)
ASB17Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. (295 aa)
CCDC126Coiled-coil domain containing 126. (140 aa)
OR5J2Olfactory receptor 5J2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (312 aa)
DPY19L3Probable C-mannosyltransferase DPY19L3; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins; Belongs to the dpy-19 family. (716 aa)
LVRNAminopeptidase Q; Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys- LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C. (990 aa)
CCDC154Coiled-coil domain containing 154. (674 aa)
IQCNIQ motif containing N. (1367 aa)
STMP1Short transmembrane mitochondrial protein 1. (47 aa)
OR5M11Olfactory receptor 5M11; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (305 aa)
OR5M10Olfactory receptor 5M10; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (315 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8; Possible involvement in extravasation of leukocytes. (824 aa)
GALNTL5Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5; Probable inactive glycosyltransferase required during spermatid development. May participate in protein loading into the acrosomes and accumulation of ubiquitin-proteasome systems around the head-tail coupling apparatus region. (443 aa)
ZNF658Zinc finger protein 658; Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'- C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply. (1059 aa)
GOLGA6L7Golgin subfamily A member 6-like protein 7; Golgin A6 family like 7; Belongs to the GOLGA6 family. (622 aa)
C2orf81Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81. (520 aa)
JAKMIP3Janus kinase and microtubule interacting protein 3; Belongs to the JAKMIP family. (844 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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