| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C11orf54 | HEPHL1 | ENSP00000331209 | ENSP00000313699 | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | 0.436 |
| C11orf54 | SMCO4 | ENSP00000331209 | ENSP00000298966 | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | 0.492 |
| C11orf54 | VSTM5 | ENSP00000331209 | ENSP00000386607 | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | 0.585 |
| HEPHL1 | C11orf54 | ENSP00000313699 | ENSP00000331209 | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | 0.436 |
| HEPHL1 | K7ERJ3_HUMAN | ENSP00000313699 | ENSP00000468280 | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | Uncharacterized protein. | 0.485 |
| HEPHL1 | SMCO4 | ENSP00000313699 | ENSP00000298966 | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | 0.400 |
| HEPHL1 | VSTM5 | ENSP00000313699 | ENSP00000386607 | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | 0.449 |
| HSD17B11 | METTL7A | ENSP00000351035 | ENSP00000448785 | Estradiol 17-beta-dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A- dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. | Methyltransferase-like protein 7A; Probable methyltransferase. | 0.481 |
| K7ERJ3_HUMAN | HEPHL1 | ENSP00000468280 | ENSP00000313699 | Uncharacterized protein. | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | 0.485 |
| K7ERJ3_HUMAN | METTL7A | ENSP00000468280 | ENSP00000448785 | Uncharacterized protein. | Methyltransferase-like protein 7A; Probable methyltransferase. | 0.427 |
| METTL7A | HSD17B11 | ENSP00000448785 | ENSP00000351035 | Methyltransferase-like protein 7A; Probable methyltransferase. | Estradiol 17-beta-dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A- dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. | 0.481 |
| METTL7A | K7ERJ3_HUMAN | ENSP00000448785 | ENSP00000468280 | Methyltransferase-like protein 7A; Probable methyltransferase. | Uncharacterized protein. | 0.427 |
| SMCO4 | C11orf54 | ENSP00000298966 | ENSP00000331209 | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | 0.492 |
| SMCO4 | HEPHL1 | ENSP00000298966 | ENSP00000313699 | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | 0.400 |
| SMCO4 | VSTM5 | ENSP00000298966 | ENSP00000386607 | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | 0.564 |
| VSTM5 | C11orf54 | ENSP00000386607 | ENSP00000331209 | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | Ester hydrolase C11orf54; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | 0.585 |
| VSTM5 | HEPHL1 | ENSP00000386607 | ENSP00000313699 | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | Ferroxidase HEPHL1; Is a copper-binding glycoprotein with ferroxidase activity. It oxidizes Fe(2+) to Fe(3+) without releasing radical oxygen species. May be involved in the regulation of intracellular iron content. | 0.449 |
| VSTM5 | SMCO4 | ENSP00000386607 | ENSP00000298966 | V-set and transmembrane domain-containing protein 5; Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines such as thin and branched types. Regulates neuronal morphogenesis and migration during cortical [...] | Single-pass membrane protein with coiled-coil domains 4; Belongs to the SMCO4 family. | 0.564 |