(6 nodes) Mixed, incl. Prominin, and Regulation of transposon integration network (Homo sapiens)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	ZNF106	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. (1883 aa)
	ZNF91	Zinc finger protein 91; Transcription factor specifically required to repress SINE- VNTR-Alu (SVA) retrotransposons: recognizes and binds SVA sequences and represses their expression by recruiting a repressive complex containing TRIM28/KAP1. May also bind the promoter of the FCGR2B gene, leading to repress its expression; however, additional evidence is required to confirm this result in vivo. Belongs to the krueppel C2H2-type zinc-finger protein family. (1191 aa)
	PROM2	Prominin-2; Prominin 2. (834 aa)
	SHROOM4	Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family. (1493 aa)
	C1orf159	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. (380 aa)
	PTCD2	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function. (388 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf159	PROM2	ENSP00000368644	ENSP00000318270	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Prominin-2; Prominin 2.	0.459
C1orf159	PTCD2	ENSP00000368644	ENSP00000370013	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	0.527
C1orf159	ZNF106	ENSP00000368644	ENSP00000263805	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	0.506
PROM2	C1orf159	ENSP00000318270	ENSP00000368644	Prominin-2; Prominin 2.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.459
PROM2	PTCD2	ENSP00000318270	ENSP00000370013	Prominin-2; Prominin 2.	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	0.422
PROM2	SHROOM4	ENSP00000318270	ENSP00000365188	Prominin-2; Prominin 2.	Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family.	0.545
PROM2	ZNF106	ENSP00000318270	ENSP00000263805	Prominin-2; Prominin 2.	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	0.510
PTCD2	C1orf159	ENSP00000370013	ENSP00000368644	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.527
PTCD2	PROM2	ENSP00000370013	ENSP00000318270	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	Prominin-2; Prominin 2.	0.422
PTCD2	ZNF106	ENSP00000370013	ENSP00000263805	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	0.463
SHROOM4	PROM2	ENSP00000365188	ENSP00000318270	Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family.	Prominin-2; Prominin 2.	0.545
SHROOM4	ZNF106	ENSP00000365188	ENSP00000263805	Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family.	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	0.488
ZNF106	C1orf159	ENSP00000263805	ENSP00000368644	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.506
ZNF106	PROM2	ENSP00000263805	ENSP00000318270	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	Prominin-2; Prominin 2.	0.510
ZNF106	PTCD2	ENSP00000263805	ENSP00000370013	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	0.463
ZNF106	SHROOM4	ENSP00000263805	ENSP00000365188	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family.	0.488
ZNF106	ZNF91	ENSP00000263805	ENSP00000300619	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	Zinc finger protein 91; Transcription factor specifically required to repress SINE- VNTR-Alu (SVA) retrotransposons: recognizes and binds SVA sequences and represses their expression by recruiting a repressive complex containing TRIM28/KAP1. May also bind the promoter of the FCGR2B gene, leading to repress its expression; however, additional evidence is required to confirm this result in vivo. Belongs to the krueppel C2H2-type zinc-finger protein family.	0.815
ZNF91	ZNF106	ENSP00000300619	ENSP00000263805	Zinc finger protein 91; Transcription factor specifically required to repress SINE- VNTR-Alu (SVA) retrotransposons: recognizes and binds SVA sequences and represses their expression by recruiting a repressive complex containing TRIM28/KAP1. May also bind the promoter of the FCGR2B gene, leading to repress its expression; however, additional evidence is required to confirm this result in vivo. Belongs to the krueppel C2H2-type zinc-finger protein family.	Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism.	0.815