(6 nodes) Mixed, incl. Neuralized, and Domain of unknown function DUF5909 network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WFDC3	WAP four-disulfide core domain 3. (231 aa)
	WFDC10B	Protein WFDC10B; WAP four-disulfide core domain 10B. (89 aa)
	NEURL2	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity). (285 aa)
	SPATA25	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family. (227 aa)
	ZSWIM1	Zinc finger SWIM-type containing 1. (485 aa)
	ZSWIM9	Uncharacterized protein ZSWIM9; Zinc finger SWIM-type containing 9. (920 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NEURL2	SPATA25	ENSP00000361596	ENSP00000361597	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	0.720
NEURL2	WFDC10B	ENSP00000361596	ENSP00000337466	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	Protein WFDC10B; WAP four-disulfide core domain 10B.	0.481
NEURL2	WFDC3	ENSP00000361596	ENSP00000243938	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	WAP four-disulfide core domain 3.	0.401
NEURL2	ZSWIM1	ENSP00000361596	ENSP00000361601	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	Zinc finger SWIM-type containing 1.	0.551
SPATA25	NEURL2	ENSP00000361597	ENSP00000361596	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	0.720
SPATA25	WFDC10B	ENSP00000361597	ENSP00000337466	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	Protein WFDC10B; WAP four-disulfide core domain 10B.	0.581
SPATA25	WFDC3	ENSP00000361597	ENSP00000243938	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	WAP four-disulfide core domain 3.	0.519
SPATA25	ZSWIM1	ENSP00000361597	ENSP00000361601	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	Zinc finger SWIM-type containing 1.	0.634
WFDC10B	NEURL2	ENSP00000337466	ENSP00000361596	Protein WFDC10B; WAP four-disulfide core domain 10B.	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	0.481
WFDC10B	SPATA25	ENSP00000337466	ENSP00000361597	Protein WFDC10B; WAP four-disulfide core domain 10B.	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	0.581
WFDC10B	WFDC3	ENSP00000337466	ENSP00000243938	Protein WFDC10B; WAP four-disulfide core domain 10B.	WAP four-disulfide core domain 3.	0.713
WFDC10B	ZSWIM1	ENSP00000337466	ENSP00000361601	Protein WFDC10B; WAP four-disulfide core domain 10B.	Zinc finger SWIM-type containing 1.	0.580
WFDC3	NEURL2	ENSP00000243938	ENSP00000361596	WAP four-disulfide core domain 3.	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	0.401
WFDC3	SPATA25	ENSP00000243938	ENSP00000361597	WAP four-disulfide core domain 3.	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	0.519
WFDC3	WFDC10B	ENSP00000243938	ENSP00000337466	WAP four-disulfide core domain 3.	Protein WFDC10B; WAP four-disulfide core domain 10B.	0.713
WFDC3	ZSWIM1	ENSP00000243938	ENSP00000361601	WAP four-disulfide core domain 3.	Zinc finger SWIM-type containing 1.	0.507
ZSWIM1	NEURL2	ENSP00000361601	ENSP00000361596	Zinc finger SWIM-type containing 1.	Neuralized-like protein 2; Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).	0.551
ZSWIM1	SPATA25	ENSP00000361601	ENSP00000361597	Zinc finger SWIM-type containing 1.	Spermatogenesis-associated protein 25; May play a role in spermatogenesis. Belongs to the SPATA25 family.	0.634
ZSWIM1	WFDC10B	ENSP00000361601	ENSP00000337466	Zinc finger SWIM-type containing 1.	Protein WFDC10B; WAP four-disulfide core domain 10B.	0.580
ZSWIM1	WFDC3	ENSP00000361601	ENSP00000243938	Zinc finger SWIM-type containing 1.	WAP four-disulfide core domain 3.	0.507