STRINGSTRING
KIF22 KIF22 ADAM7 ADAM7 FAM83E FAM83E LCN9 LCN9 TRIM62 TRIM62 LCN15 LCN15 TTLL11 TTLL11 LCN6 LCN6 OBP2A OBP2A APOD APOD TEDDM1 TEDDM1 LCN12 LCN12 OLFM1 OLFM1 SLC46A2 SLC46A2 CST11 CST11 LCNL1 LCNL1 LCN10 LCN10 GRAPL GRAPL ZNF362 ZNF362 ZFP37 ZFP37 LCN8 LCN8 OBP2B OBP2B SERTM2 SERTM2 ENSP00000493691 ENSP00000493691 OR51C1P OR51C1P
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KIF22Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. (665 aa)
ADAM7Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). (754 aa)
FAM83EProtein FAM83E; May play a role in MAPK signaling. Belongs to the FAM83 family. (478 aa)
LCN9Epididymal-specific lipocalin-9; Lipocalin 9. (176 aa)
TRIM62E3 ubiquitin-protein ligase TRIM62; E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2; Belongs to the TRIM/RBCC family. (475 aa)
LCN15Lipocalin-15; Lipocalin 15. (184 aa)
TTLL11Tubulin polyglutamylase TTLL11; Polyglutamase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Generates long side-chains (By similarity). (800 aa)
LCN6Epididymal-specific lipocalin-6; May play a role in male fertility. (163 aa)
OBP2AOdorant binding protein 2A; Belongs to the calycin superfamily. Lipocalin family. (228 aa)
APODApolipoprotein D; APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (189 aa)
TEDDM1Transmembrane epididymal protein 1. (273 aa)
LCN12Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity). (192 aa)
OLFM1Noelin; Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity). (485 aa)
SLC46A2Thymic stromal cotransporter homolog; May act as a transporter; Belongs to the major facilitator superfamily. SLC46A family. (475 aa)
CST11Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family. (138 aa)
LCNL1Lipocalin-like 1 protein; Lipocalin like 1; Belongs to the calycin superfamily. Lipocalin family. (164 aa)
LCN10Epididymal-specific lipocalin-10; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. (200 aa)
GRAPLGRB2-related adapter protein-like; GRB2 related adaptor protein like. (118 aa)
ZNF362Zinc finger protein 362; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (420 aa)
ZFP37Zinc finger protein 37 homolog; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (645 aa)
LCN8Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. (175 aa)
OBP2BOdorant-binding protein 2b; Probably binds and transports small hydrophobic volatile molecules; Belongs to the calycin superfamily. Lipocalin family. (170 aa)
SERTM2Serine rich and transmembrane domain containing 2. (89 aa)
ENSP00000493691Uncharacterized protein. (985 aa)
OR51C1POlfactory receptor family 51 subfamily C member 1 pseudogene. (312 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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