STRINGSTRING
KIF22 KIF22 ADAM7 ADAM7 LCN9 LCN9 LCN15 LCN15 LCN6 LCN6 OBP2A OBP2A APOD APOD TEDDM1 TEDDM1 LCN12 LCN12 CST11 CST11 LCN10 LCN10 LCN8 LCN8 OBP2B OBP2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KIF22Kinesin-like protein KIF22; Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells. (665 aa)
ADAM7Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (By similarity). (754 aa)
LCN9Epididymal-specific lipocalin-9; Lipocalin 9. (176 aa)
LCN15Lipocalin-15; Lipocalin 15. (184 aa)
LCN6Epididymal-specific lipocalin-6; May play a role in male fertility. (163 aa)
OBP2AOdorant binding protein 2A; Belongs to the calycin superfamily. Lipocalin family. (228 aa)
APODApolipoprotein D; APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (189 aa)
TEDDM1Transmembrane epididymal protein 1. (273 aa)
LCN12Epididymal-specific lipocalin-12; Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity). (192 aa)
CST11Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family. (138 aa)
LCN10Epididymal-specific lipocalin-10; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. (200 aa)
LCN8Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. (175 aa)
OBP2BOdorant-binding protein 2b; Probably binds and transports small hydrophobic volatile molecules; Belongs to the calycin superfamily. Lipocalin family. (170 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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