Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARHGAP11B | FAM72B | ENSP00000392760 | ENSP00000358397 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | 0.615 |
| ARHGAP11B | FAM72C | ENSP00000392760 | ENSP00000463032 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | 0.616 |
| ARHGAP11B | FAM72D | ENSP00000392760 | ENSP00000383682 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | Protein FAM72D; Family with sequence similarity 72 member D. | 0.583 |
| ARHGAP11B | NOTCH2NLB | ENSP00000392760 | ENSP00000472124 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | Notch homolog 2 N-terminal-like protein B; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...] | 0.675 |
| ARHGAP11B | SRGAP2B | ENSP00000392760 | ENSP00000493121 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | SLIT-ROBO Rho GTPase-activating protein 2B; May regulate cell migration and differentiation through interaction with and inhibition of SRGAP2. | 0.575 |
| ARHGAP11B | SRGAP2C | ENSP00000392760 | ENSP00000478290 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | SLIT-ROBO Rho GTPase-activating protein 2C; Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and density and may have implications for cognition, learning and memory. | 0.720 |
| FAM72B | ARHGAP11B | ENSP00000358397 | ENSP00000392760 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | 0.615 |
| FAM72B | FAM72C | ENSP00000358397 | ENSP00000463032 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | 0.999 |
| FAM72B | FAM72D | ENSP00000358397 | ENSP00000383682 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | Protein FAM72D; Family with sequence similarity 72 member D. | 0.640 |
| FAM72B | NOTCH2NLB | ENSP00000358397 | ENSP00000472124 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | Notch homolog 2 N-terminal-like protein B; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...] | 0.418 |
| FAM72B | SRGAP2B | ENSP00000358397 | ENSP00000493121 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | SLIT-ROBO Rho GTPase-activating protein 2B; May regulate cell migration and differentiation through interaction with and inhibition of SRGAP2. | 0.589 |
| FAM72B | SRGAP2C | ENSP00000358397 | ENSP00000478290 | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | SLIT-ROBO Rho GTPase-activating protein 2C; Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and density and may have implications for cognition, learning and memory. | 0.651 |
| FAM72C | ARHGAP11B | ENSP00000463032 | ENSP00000392760 | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | 0.616 |
| FAM72C | FAM72B | ENSP00000463032 | ENSP00000358397 | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | 0.999 |
| FAM72C | FAM72D | ENSP00000463032 | ENSP00000383682 | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | Protein FAM72D; Family with sequence similarity 72 member D. | 0.626 |
| FAM72C | SRGAP2B | ENSP00000463032 | ENSP00000493121 | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | SLIT-ROBO Rho GTPase-activating protein 2B; May regulate cell migration and differentiation through interaction with and inhibition of SRGAP2. | 0.590 |
| FAM72C | SRGAP2C | ENSP00000463032 | ENSP00000478290 | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | SLIT-ROBO Rho GTPase-activating protein 2C; Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the rate of spine maturation and indirectly increases neuronal migration. Changes dendritic spine morphology and density and may have implications for cognition, learning and memory. | 0.517 |
| FAM72D | ARHGAP11B | ENSP00000383682 | ENSP00000392760 | Protein FAM72D; Family with sequence similarity 72 member D. | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | 0.583 |
| FAM72D | FAM72B | ENSP00000383682 | ENSP00000358397 | Protein FAM72D; Family with sequence similarity 72 member D. | Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family. | 0.640 |
| FAM72D | FAM72C | ENSP00000383682 | ENSP00000463032 | Protein FAM72D; Family with sequence similarity 72 member D. | Protein FAM72C; Family with sequence similarity 72 member C; Belongs to the FAM72 family. | 0.626 |
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