STRINGSTRING
ZFAND1 ZFAND1 FMO5 FMO5 TATDN1 TATDN1 AKIP1 AKIP1 ANKRD35 ANKRD35 GPR89B GPR89B NPIPB11 NPIPB11 ZFP92 ZFP92 ACP6 ACP6 RNF115 RNF115 NBPF10 NBPF10 LIX1L LIX1L ANKRD34A ANKRD34A NBPF11 NBPF11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFAND1AN1-type zinc finger protein 1; Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress. Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome. This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during [...] (268 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming] 5; In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. (533 aa)
TATDN1Putative deoxyribonuclease TATDN1; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. (297 aa)
AKIP1A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. (210 aa)
ANKRD35Ankyrin repeat domain 35. (1001 aa)
GPR89BG protein-coupled receptor 89B. (455 aa)
NPIPB11Nuclear pore complex interacting protein family member B11. (1161 aa)
ZFP92Zinc finger protein 92 homolog; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (416 aa)
ACP6Lysophosphatidic acid phosphatase type 6; Hydrolyzes lysophosphatidic acid (LPA) containing a medium length fatty acid chain to the corresponding monoacylglycerol. Has highest activity with lysophosphatidic acid containing myristate (C14:0), monounsaturated oleate (C18:1) or palmitate (C16:0), and lower activity with C18:0 and C6:0 lysophosphatidic acid. Belongs to the histidine acid phosphatase family. (428 aa)
RNF115E3 ubiquitin-protein ligase RNF115; E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys- 48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4. (304 aa)
NBPF10Neuroblastoma breakpoint family member 10; NBPF member 10. (3795 aa)
LIX1LLIX1-like protein; Limb and CNS expressed 1 like; Belongs to the LIX1 family. (337 aa)
ANKRD34AAnkyrin repeat domain 34A. (496 aa)
NBPF11Neuroblastoma breakpoint family member 11; NBPF member 11; Belongs to the NBPF family. (865 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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