STRINGSTRING
PHPT1 PHPT1 TMEM141 TMEM141 MAMDC4 MAMDC4 CCDC183 CCDC183 RABL6 RABL6 TBRG1 TBRG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHPT114 kDa phosphohistidine phosphatase; Exhibits phosphohistidine phosphatase activity. Belongs to the janus family. (125 aa)
TMEM141Transmembrane protein 141. (108 aa)
MAMDC4Apical endosomal glycoprotein; Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia. (1137 aa)
CCDC183Coiled-coil domain containing 183. (534 aa)
RABL6Rab-like protein 6; May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A. (730 aa)
TBRG1Transforming growth factor beta regulator 1; Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability; Belongs to the TBRG1 family. (411 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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