(7 nodes) Mixed, incl. Megalencephalic leukoencephalopathy with subcortical cysts 2B, and Negative regulation of synapse maturation network (Homo sapiens)

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second shell of interactors

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Your Input:
	HEPACAM	Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation. (416 aa)
	NEUROD2	Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down- regulating REST expression. Plays a role in the establishment and maturation of thalamocor [...] (382 aa)
	LRRC69	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69. (191 aa)
	PRRG3	Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3. (231 aa)
	C1orf87	Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87. (546 aa)
	ATAD3C	ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family. (411 aa)
	GDPGP1	GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells. (385 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD3C	GDPGP1	ENSP00000368062	ENSP00000452793	ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family.	GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.	0.461
ATAD3C	LRRC69	ENSP00000368062	ENSP00000343221	ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family.	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	0.540
C1orf87	HEPACAM	ENSP00000360244	ENSP00000298251	Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87.	Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.	0.493
GDPGP1	ATAD3C	ENSP00000452793	ENSP00000368062	GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.	ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family.	0.461
GDPGP1	LRRC69	ENSP00000452793	ENSP00000343221	GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	0.665
HEPACAM	C1orf87	ENSP00000298251	ENSP00000360244	Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.	Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87.	0.493
HEPACAM	NEUROD2	ENSP00000298251	ENSP00000306754	Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.	Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down- regulating REST expression. Plays a role in the establishment and maturation of thalamocor [...]	0.501
LRRC69	ATAD3C	ENSP00000343221	ENSP00000368062	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family.	0.540
LRRC69	GDPGP1	ENSP00000343221	ENSP00000452793	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.	0.665
LRRC69	PRRG3	ENSP00000343221	ENSP00000359378	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3.	0.650
NEUROD2	HEPACAM	ENSP00000306754	ENSP00000298251	Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down- regulating REST expression. Plays a role in the establishment and maturation of thalamocor [...]	Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.	0.501
NEUROD2	PRRG3	ENSP00000306754	ENSP00000359378	Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down- regulating REST expression. Plays a role in the establishment and maturation of thalamocor [...]	Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3.	0.665
PRRG3	LRRC69	ENSP00000359378	ENSP00000343221	Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3.	Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69.	0.650
PRRG3	NEUROD2	ENSP00000359378	ENSP00000306754	Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3.	Neurogenic differentiation factor 2; Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down- regulating REST expression. Plays a role in the establishment and maturation of thalamocor [...]	0.665