STRINGSTRING
CRNN CRNN SPINK7 SPINK7 DEPP1 DEPP1 TMPRSS11B TMPRSS11B CAPN14 CAPN14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRNNCornulin; Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. Regulates proliferation induced by proinflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways ; Belongs to the S100-fused protein family. (495 aa)
SPINK7Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor. (85 aa)
DEPP1Protein DEPP1; Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS. (212 aa)
TMPRSS11BTransmembrane protease serine 11B; Serine protease. (416 aa)
CAPN14Calpain-14; Calcium-regulated non-lysosomal thiol-protease. (684 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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