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| | PAGE4 | P antigen family member 4; Intrinsically disordered protein that potentiates the transcriptional activator activity of JUN. Protects cells from stress-induced apoptosis by inhibiting reactive oxygen species (ROS) production and via regulation of the MAPK signaling pathway. (102 aa) |
| | MAGEA9 | Melanoma-associated antigen 9; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. (315 aa) |
| | MAGEA10 | Melanoma-associated antigen 10; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. (369 aa) |
| | CTAG2 | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. (210 aa) |
| | OSER1 | Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1. (292 aa) |
| | INTS13 | Integrator complex subunit 13; Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. (706 aa) |
| | CT55 | Cancer/testis antigen 55. (264 aa) |
| | GMCL1 | Germ cell-less protein-like 1; Possible function in spermatogenesis. Enhances the degradation of MDM2 and increases the amount of p53 probably by modulating the nucleocytoplasmic transport (By similarity). (515 aa) |
| | ZNF117 | Zinc finger protein 117; May be involved in transcriptional regulation. (483 aa) |
| | MAGEC1 | Melanoma-associated antigen C1; MAGE family member C1. (1142 aa) |
| | XAGE2 | X antigen family member 2. (111 aa) |
| | PAGE5 | PAGE family member 5; Belongs to the GAGE family. (130 aa) |
| | MEMO1 | Protein MEMO1; May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration. (297 aa) |
| | BRI3 | Brain protein I3; Participates in tumor necrosis factor-alpha (TNF)-induced cell death. May be a target of Wnt/beta-catenin signaling in the liver ; Belongs to the BRI3 family. (125 aa) |
| | SSX3 | Protein SSX3; Could act as a modulator of transcription; Belongs to the SSX family. (188 aa) |
| | TSC22D4 | TSC22 domain family protein 4; Transcriptional repressor. (395 aa) |
| | USP32 | Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family. (1604 aa) |
| | XAGE3 | X antigen family member 3. (111 aa) |
| | SPACA5B | Sperm acrosome associated 5B; Belongs to the glycosyl hydrolase 22 family. (159 aa) |
| | INTS6 | Integrator complex subunit 6; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth. (887 aa) |
| | SSX5 | Protein SSX5; Could act as a modulator of transcription. (229 aa) |
| | RPRML | Reprimo-like protein; Reprimo like. (120 aa) |
| | INTS3 | Integrator complex subunit 3; Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (1042 aa) |
| | GPR89A | Golgi pH regulator A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family. (455 aa) |
| | VCX2 | Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family. (139 aa) |
| | SAGE1 | Sarcoma antigen 1. (904 aa) |
| | PRSS50 | Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family. (385 aa) |
| | C7orf61 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. (206 aa) |
| | INTS5 | Integrator complex subunit 5; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (1019 aa) |
| | CTAG1B | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. (180 aa) |
| | SS18L1 | Calcium-responsive transactivator; Transcriptional activator which is required for calcium- dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is depho [...] (396 aa) |
| | MAGEA2B | Melanoma-associated antigen 2; Reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Also represses p73/TP73 activity. Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination by TRIM28 potentially in presence of Ubl-conjugating enzyme UBE2H. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal d [...] (314 aa) |
| | SSX2 | SSX family member 2. (223 aa) |
| | AIDA | Axin interactor, dorsalization-associated protein; Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin- independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity). (306 aa) |
| | C7orf26 | Uncharacterized protein C7orf26; Chromosome 7 open reading frame 26. (449 aa) |
| | NRN1L | Neuritin-like protein; Neuritin 1 like. (165 aa) |
| | MAGEA11 | Melanoma-associated antigen 11; Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression. (429 aa) |
| | MAGEA1 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. (309 aa) |
| | SLITRK4 | SLIT and NTRK-like protein 4; It is involved in synaptogenesis and promotes synapse differentiation. Suppresses neurite outgrowth (By similarity); Belongs to the SLITRK family. (837 aa) |
| | MOB3A | MOB kinase activator 3A; May regulate the activity of kinases. (217 aa) |
| | TXNDC15 | Thioredoxin domain-containing protein 15; Acts as a positive regulator of ciliary hedgehog signaling (By similarity). Involved in ciliogenesis. (360 aa) |
| | SPANXC | Sperm protein associated with the nucleus on the X chromosome C; SPANX family member C; Belongs to the SPAN-X family. (97 aa) |
| | PLAC1 | Placenta-specific protein 1; May play a role in placental development. Belongs to the PLAC1 family. (212 aa) |
| | LDLRAD4 | Low-density lipoprotein receptor class A domain-containing protein 4; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. [...] (306 aa) |
| | MAGEA4 | Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. (317 aa) |
| | TSC22D2 | TSC22 domain family member 2. (780 aa) |
| | MAGEC2 | Melanoma-associated antigen C2; Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex. (373 aa) |
| | ZNF630 | Zinc finger protein 630; May be involved in transcriptional regulation. (657 aa) |
| | INTS7 | Integrator complex subunit 7; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Plays a role in DNA damage response (DDR) signaling during the S phase. May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex. (962 aa) |
| | LEMD1 | LEM domain containing 1. (181 aa) |
| | CSAG1 | Putative chondrosarcoma-associated gene 1 protein; Chondrosarcoma associated gene 1. (78 aa) |
| | DDX43 | Probable ATP-dependent RNA helicase DDX43; DEAD-box helicase 43. (648 aa) |
| | PASD1 | Circadian clock protein PASD1; Functions as a suppressor of the biological clock that drives the daily circadian rhythms of cells throughout the body. Acts as a nuclear repressor of the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock components. Inhibits circadian clock function in cancer cells, when overexpressed. (773 aa) |
| | CXorf40B | Protein CXorf40B. (158 aa) |
| | HSFX1 | Heat shock transcription factor family, X-linked 1. (423 aa) |
| | AFF2 | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. (1311 aa) |
| | FMR1NB | Fragile X mental retardation 1 neighbor protein; FMR1 neighbor. (255 aa) |
| | SPANXN1 | Sperm protein associated with the nucleus on the X chromosome N1; SPANX family member N1; Belongs to the SPAN-X family. (72 aa) |
| | SPANXD | Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family. (97 aa) |
| | SPANXA2 | Sperm protein associated with the nucleus on the X chromosome A; SPANX family member A2; Belongs to the SPAN-X family. (97 aa) |
| | SPANXA1 | Sperm protein associated with the nucleus, X-linked, family member A1. (97 aa) |
| | FAM209B | Protein FAM209B; Family with sequence similarity 209 member B. (171 aa) |
| | INIP | SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. (104 aa) |
| | PAGE3 | PAGE family member 3. (113 aa) |
| | PAGE2 | PAGE family member 2. (111 aa) |
| | PAGE2B | PAGE family member 2B; Belongs to the GAGE family. (111 aa) |
| | SPANXN5 | Sperm protein associated with the nucleus on the X chromosome N5; SPANX family member N5; Belongs to the SPAN-X family. (72 aa) |
| | XAGE1A | X antigen family member 1A. (81 aa) |
| | XAGE1B | X antigen family member 1B. (81 aa) |
| | PAGE1 | PAGE family member 1. (146 aa) |
| | SSX1 | Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family. (188 aa) |
| | MAGEB1 | Melanoma-associated antigen B1; MAGE family member B1. (347 aa) |
| | MAGEB2 | Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. (319 aa) |
| | NRBP1 | Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (543 aa) |
| | NABP2 | SOSS complex subunit B1; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-s [...] (211 aa) |
| | MLF1 | Myeloid leukemia factor 1; Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus; Belongs to the MLF family. (299 aa) |
| | MAGEA12 | Melanoma-associated antigen 12; Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines. (314 aa) |
| | INTS10 | Integrator complex subunit 10; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex. (710 aa) |
| | C2orf73 | Uncharacterized protein C2orf73; Chromosome 2 open reading frame 73. (287 aa) |
| | INTS1 | Integrator complex subunit 1; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (2190 aa) |
| | CT47A4 | Cancer/testis antigen family 47 member A4. (288 aa) |
| | CT47A5 | Cancer/testis antigen family 47 member A5. (288 aa) |
| | CT47A7 | Cancer/testis antigen family 47 member A7. (288 aa) |
| | CT47A1 | Cancer/testis antigen family 47 member A1. (288 aa) |
| | TSC22D1 | TSC22 domain family protein 1; Transcriptional repressor. Acts on the C-type natriuretic peptide (CNP) promoter. (1073 aa) |
| | CT47A3 | Cancer/testis antigen family 47 member A3. (288 aa) |
| | CT47A6 | Cancer/testis antigen family 47 member A6. (288 aa) |
| | CT47A8 | Cancer/testis antigen family 47 member A8. (288 aa) |
| | SS18L2 | SS18-like protein 2; SS18 like 2. (77 aa) |
| | NABP1 | SOSS complex subunit B2; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-s [...] (204 aa) |
| | SPANXB1 | Sperm protein associated with the nucleus on the X chromosome B1; SPANX family member B1. (103 aa) |
| | SPANXN4 | Sperm protein associated with the nucleus on the X chromosome N4; SPANX family member N4; Belongs to the SPAN-X family. (99 aa) |
| | HIPK1 | Homeodomain-interacting protein kinase 1; Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by [...] (1210 aa) |
| | CT47A9 | Cancer/testis antigen family 47 member A9. (288 aa) |
| | CT47A11 | Cancer/testis antigen family 47 member A11. (288 aa) |
| | CT47A10 | Cancer/testis antigen family 47 member A10. (288 aa) |
| | NRBP2 | Nuclear receptor-binding protein 2; May regulate apoptosis of neural progenitor cells during their differentiation. (501 aa) |
| | INTS2 | Integrator complex subunit 2; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (1204 aa) |
| | CT47A2 | Cancer/testis antigen family 47 member A2. (288 aa) |
| | INTS12 | Integrator complex subunit 12; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (462 aa) |
| | TSPYL6 | Testis-specific Y-encoded-like protein 6; TSPY like 6; Belongs to the nucleosome assembly protein (NAP) family. (410 aa) |
| | MAGED4B | Melanoma-associated antigen D4; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. (757 aa) |
| | CXorf40A | Protein CXorf40A; May have an important role of cell protection in inflammation reaction. (158 aa) |
| | CCDC153 | Coiled-coil domain containing 153; Belongs to the UPF0610 family. (210 aa) |
| | C1orf216 | UPF0500 protein C1orf216; Chromosome 1 open reading frame 216. (229 aa) |
| | CT45A5 | Cancer/testis antigen family 45 member A5. (189 aa) |
| | INTS9 | Integrator complex subunit 9; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. INTS9 subfamily. (658 aa) |
| | HMBOX1 | Homeobox-containing protein 1; Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (By similarity). Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles i [...] (443 aa) |
| | INTS8 | Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'- box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. (995 aa) |
| | INTS4 | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. (963 aa) |
| | MAGEA8 | Melanoma-associated antigen 8; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. (318 aa) |
| | INTS11 | Integrator complex subunit 11; Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex ; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta [...] (606 aa) |
| | C12orf54 | Uncharacterized protein C12orf54; Chromosome 12 open reading frame 54. (127 aa) |
| | NPIPA3 | Nuclear pore complex interacting protein family member A3. (350 aa) |
| | TPPP3 | Tubulin polymerization-promoting protein family member 3; Regulator of microtubule dynamic that has microtubule bundling activity. Required for embryo implantation; possibly by regulating beta-catenin (By similarity). Also required for decidualization via regulation of beta- catenin. (176 aa) |
| | SSX4 | Protein SSX4; Could act as a modulator of transcription. (188 aa) |
| | HSFX2 | Heat shock transcription factor family, X-linked 2. (423 aa) |
| | SSX4B | SSX family member 4B. (188 aa) |
| | CTAG1A | Cancer/testis antigen 1A. (180 aa) |
| | CT45A1 | Cancer/testis antigen family 45 member A1. (189 aa) |
| | MAGEA9B | MAGE family member A9B. (315 aa) |
| | CT45A3 | Cancer/testis antigen family 45 member A3; Belongs to the CT45 family. (189 aa) |
| | TMEM185A | Transmembrane protein 185A; Belongs to the TMEM185 family. (350 aa) |
| | MAGED4 | MAGE family member D4. (757 aa) |
| | ZNF83 | Zinc finger protein 83; May be involved in transcriptional regulation. (516 aa) |
| | MAGEA3 | Melanoma-associated antigen 3; Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. (314 aa) |
| | IGHV3OR16-9 | Immunoglobulin heavy variable 3/OR16-9. (96 aa) |
| | SSX2B | SSX family member 2B. (223 aa) |
| | TBC1D3B | TBC1 domain family member 3B; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). (549 aa) |
| | TBC1D3 | TBC1 domain family member 3; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11. (549 aa) |
| | CT45A6 | Cancer/testis antigen family 45 member A6. (189 aa) |
| | MAGEA6 | Melanoma-associated antigen 6; Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. (314 aa) |
| | CT45A8 | Cancer/testis antigen family 45 member A8. (189 aa) |
| | CT45A7 | Cancer/testis antigen family 45 member A7. (189 aa) |
| | TBC1D3C | TBC1 domain family member 3C. (549 aa) |
| | CT45A2 | Cancer/testis antigen family 45 member A2. (189 aa) |
| | CT45A9 | Cancer/testis antigen family 45 member A9. (189 aa) |
| | CT45A10 | Cancer/testis antigen family 45 member A10. (189 aa) |
| | GAGE1 | G antigen 1; Antigen, recognized on melanoma by autologous cytolytic T- lymphocytes. Completely silent in normal adult tissues, except testis; Belongs to the GAGE family. (117 aa) |
| | MAGEA2 | MAGE family member A2. (314 aa) |
| | SPATA31D4 | Spermatogenesis-associated protein 31D4; May play a role in spermatogenesis; Belongs to the SPATA31 family. (917 aa) |
| | HSFX4 | Heat shock transcription factor family, X-linked member 4. (333 aa) |
| | CCDC197 | Uncharacterized protein CCDC197; Coiled-coil domain containing 197. (272 aa) |
| | PPP1R2C | Protein phosphatase inhibitor 2 family member C; Functions as a protein phosphatase inhibitor. It inhibits activity of the catalytic subunit of PP1 and weakly inhibits the activity of myosin-associated phosphates. (202 aa) |
| | INTS6L | Integrator complex subunit 6 like. (898 aa) |
| | CSAG2 | Chondrosarcoma-associated gene 2/3 protein; CSAG family member 2. (110 aa) |
| | CSAG3 | Chondrosarcoma-associated gene 2/3 protein; Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype. (110 aa) |
| | DSE | Dermatan-sulfate epimerase; Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. (958 aa) |
| | INTS14 | Integrator complex subunit 14; Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing; Belongs to the INTS14 family. (461 aa) |
