(20 nodes) Mostly uncharacterized, incl. Photosensitive epilepsy, and Aspartate-rich protein 1-like network (Homo sapiens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3orf22	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22. (141 aa)
	SH2D7	SH2 domain containing 7. (451 aa)
	SPDYE4	Speedy protein E4; speedy/RINGO cell cycle regulator family member E4; Belongs to the Speedy/Ringo family. (237 aa)
	KIAA0825	Uncharacterized protein KIAA0825; KIAA0825. (324 aa)
	SPATA12	Spermatogenesis-associated protein 12; Spermatogenesis associated 12. (190 aa)
	LRRC27	Leucine-rich repeat-containing protein 27; Leucine rich repeat containing 27. (530 aa)
	C9orf50	Uncharacterized protein C9orf50; Chromosome 9 open reading frame 50. (431 aa)
	OR5C1	Olfactory receptor 5C1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. (320 aa)
	CLPSL1	Colipase-like protein 1; Colipase like 1; Belongs to the colipase family. (121 aa)
	C22orf42	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42. (251 aa)
	SHISAL2B	Protein shisa-like-2B; Shisa like 2B. (160 aa)
	CHD2	Chromodomain-helicase-DNA-binding protein 2; DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). (1828 aa)
	CC2D2B	Protein CC2D2B; Coiled-coil and C2 domain containing 2B. (401 aa)
	C4orf51	Uncharacterized protein C4orf51; Chromosome 4 open reading frame 51. (202 aa)
	C1orf167	Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167. (1468 aa)
	C21orf62	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62. (219 aa)
	AMER2	APC membrane recruitment protein 2; Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex; Belongs to the Amer family. (671 aa)
	C12orf56	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56. (622 aa)
	ANKRD62	Ankyrin repeat domain 62. (917 aa)
	SMIM17	Small integral membrane protein 17. (118 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMER2	C9orf50	ENSP00000426528	ENSP00000361556	APC membrane recruitment protein 2; Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex; Belongs to the Amer family.	Uncharacterized protein C9orf50; Chromosome 9 open reading frame 50.	0.421
ANKRD62	C12orf56	ENSP00000467740	ENSP00000446101	Ankyrin repeat domain 62.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.543
ANKRD62	C1orf167	ENSP00000467740	ENSP00000414909	Ankyrin repeat domain 62.	Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167.	0.565
ANKRD62	C21orf62	ENSP00000467740	ENSP00000418653	Ankyrin repeat domain 62.	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	0.477
ANKRD62	C22orf42	ENSP00000467740	ENSP00000371529	Ankyrin repeat domain 62.	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	0.507
ANKRD62	C3orf22	ENSP00000467740	ENSP00000316644	Ankyrin repeat domain 62.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.589
ANKRD62	CC2D2B	ENSP00000467740	ENSP00000386988	Ankyrin repeat domain 62.	Protein CC2D2B; Coiled-coil and C2 domain containing 2B.	0.509
ANKRD62	CLPSL1	ENSP00000467740	ENSP00000362968	Ankyrin repeat domain 62.	Colipase-like protein 1; Colipase like 1; Belongs to the colipase family.	0.479
ANKRD62	LRRC27	ENSP00000467740	ENSP00000357603	Ankyrin repeat domain 62.	Leucine-rich repeat-containing protein 27; Leucine rich repeat containing 27.	0.419
ANKRD62	SH2D7	ENSP00000467740	ENSP00000327846	Ankyrin repeat domain 62.	SH2 domain containing 7.	0.507
ANKRD62	SHISAL2B	ENSP00000467740	ENSP00000373726	Ankyrin repeat domain 62.	Protein shisa-like-2B; Shisa like 2B.	0.445
ANKRD62	SMIM17	ENSP00000467740	ENSP00000471126	Ankyrin repeat domain 62.	Small integral membrane protein 17.	0.527
ANKRD62	SPATA12	ENSP00000467740	ENSP00000335392	Ankyrin repeat domain 62.	Spermatogenesis-associated protein 12; Spermatogenesis associated 12.	0.446
ANKRD62	SPDYE4	ENSP00000467740	ENSP00000329522	Ankyrin repeat domain 62.	Speedy protein E4; speedy/RINGO cell cycle regulator family member E4; Belongs to the Speedy/Ringo family.	0.480
C12orf56	ANKRD62	ENSP00000446101	ENSP00000467740	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Ankyrin repeat domain 62.	0.543
C12orf56	C1orf167	ENSP00000446101	ENSP00000414909	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167.	0.544
C12orf56	C21orf62	ENSP00000446101	ENSP00000418653	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	0.507
C12orf56	C22orf42	ENSP00000446101	ENSP00000371529	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	0.544
C12orf56	C3orf22	ENSP00000446101	ENSP00000316644	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.620
C12orf56	C9orf50	ENSP00000446101	ENSP00000361556	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C9orf50; Chromosome 9 open reading frame 50.	0.435